@sciencex.bsky.social ex.bsky.social picked up our #ptychography paper on imaging the atomic-scale roughness in transistor channels in 3D, in a single scan and without having to tilt the sample. ⚛️
Atomic‑scale nickel.
Zero precious metals.
Serious fuel‑cell power—thanks in part to CCMR tools
news.cornell.edu/stories/2026...
Cryo-FIB lamellae enable ultra-high excitation laser intensities for cryogenic super-resolution fluorescence imaging www.biorxiv.org/content/10.64898/2026.04...
Too cool!
Save the date: NYC-ISB26 Integrative Structural Biology symposium - Oct 8-9, 2026
Registration coming soon.
Integrative structural biology is a powerful approach toward understanding biological macromolecular systems by bridging structural biology and biophysical methods.
nysbc.org/nyc-isb26/
Friends on this side of the pond (US) ... any of you have a K2 Digitizer around you'd be willing to part with? Ideally manufactured from 2016 onwards. If so, feel free to let me know or if you come across @davidamuller.bsky.social somewhere in the world :). Thanks in advance!!
Yue!!!!!! ❤️❤️❤️❤️
Woohoo!!!! Team reciprocal TEM ftw.
ahhh, where Grazul's dogs go when they're done with their mission on this planet. Good to know the Nion still has more life left in it.
I agree. The Nion (and before them, the VG) came to mind when I said the part about reciprocal TEM.
For research and teaching!! I wonder where out Nion ended at @davidamuller.bsky.social
The concept that STEM is reciprocal to TEM is easier to explain with a Nion Column
At one point, I even did electron microscopy in vacuum AND in air (we had an airSEM ... RIP).
And, if I could go back in time and hand a letter of encouragement to my younger self, I'd say: you will read about EM, my dear young self, and it'll blow your mind, and you will become a trained microscopist and work for a living teaching others what you've learned. I'm still amazed by this
Ha! just realized that not only and I bilingual in (transmission) electron microscopy (TEM/STEM), I'm also bilingual in TEMperatures (🤣🤣, RT and cryo), AND bilingual in scanning and transmission electron microscopy.
Our latest @biorxivpreprint.bsky.social: "Prion-like transmission of human tau strains in the mouse brain" 🥳
With Michel Goedert and Masato Hasegawa.
www.biorxiv.org/content/10.6...
Now, even though I say funny things about STEM, I gotta tell you, it's is fun to do, beautiful to collect data in, and I love being able to be bilingual in electron microscopy 😝😝 (TEM and STEM).
Things I say when I'm explaining TEM vs STEM: well, you can think of STEM as reciprocal TEM (always makes people lol). And: oh yeah, because STEM folks don't call it beam, they call it probe, and they don't list the whole beam, just the angle, in mrad 😝
Took a little bit of franken-doing, but, I have two used but in very used condition racks in the old dishwasher. Not more rusted racks. There was blood shed (mine, ofc). But, I did it!
It's really adorable when my son comes to me with a request that I fix something and, as much as I can, I'll give it my all. I remind him that we're all capable of doing great things, regardless of our sex/gender. I want him to know that his dad can cook, and I can fix things and vice versa.
My son was very happy and surprised I'd been able to fix the car. His dad is a pretty good fixer. But when he can't figure something out, he'll bring it to me. I'll take a look and see if he missed something or if something is broken beyond repair
Those little things, taking stuff apart, finding out what's misbehaving, putting stuff back together, etc, it makes me happy. And I'm glad I've come across both a place and people who encourage and celebrate that kind of curiosity and abilities.
I found a quick tutorial on the same car, took some covers off, checked the chip, reseated a small antenna, put the covers back on, and boom, now it was running.
Then, my son had an RC car he got a couple of years ago. He wanted to play with it again, but we likely left some batteries in it, which went kaput. His dad did a bang up job cleaniner therminals, but it still didn't work.
Today, I again channeled my inner Lena. Twice. First, I'd ordered a replacement rack for the old dishwasher at home (orig one had some exposed rusty parts and I became concerned of metals contaminating our dishes). Part fit like a glove.
But, I decided to channel my inner Lena (the goddess capable of fixing and diagnosing stuff in the lab/scope/detector/life), showed the boss and after packing it all up, the darn thing has maintained temps properly (AFAIK).
Turns out, we were getting a cooling error. And wouldn't you know it, one of the connections to the board (an ADC board) was not tighly bolted, as it should. Now, did I know exactly what I was doing? No. Was my colleague a wee skeptical. Sure.
Don't get me wrong, I love biology. A lot. But sometimes I wonder, if I had believed in myself enough, if I couldn't cut it as a mechE. Not too long ago, one of our detectors was acting up. One of my colleagues and I decided to take it apart and check things out, see if anything obvious jumped out
Hitchhiker's guide to synchrotron and FEL light sources for quantum technology is now available - A listing of network of all Synchrotron Radiation and Free Electron Laser user facilities in Europe - Learn More zurl.co/KKmEi
when you keep old AF emails and can search, find, and share them with your labbies so they can get shizzle moving. I'm like my mom in that sense, except she keeps stuff and I keep messages 🤣