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Posts by Jay Roshe

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STOMP The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

Seems like ARPA-H STOMP's mission is important: '"What if we could detect, understand the health impacts of, and remove toxic microplastics from the body?"

arpa-h.gov/explore-fund...

23 hours ago 1 0 1 0
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Biomarkers of Aging Consortium Establishing Reliable Biomarkers of Aging for Longevity Interventions.

Biomarkers of Aging Consortium has started uploading recordings from the Oct. 2025 conference: www.youtube.com/@Biomarkerso...

3 days ago 0 0 0 0
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Registration is now open for the 2026 JAX–NYSCF Conference. 🧬

Marking the anniversary of iPSC discovery, this year’s meeting brings together global leaders in stem cell science to share breakthroughs and shape what’s next in translational research.

Join us: https://go.jax.org/jax-nyscf-conf

5 days ago 2 1 0 0

You're right that age-related diseases are projected to increase dramatically with an increasingly older population. That's why Congress has to protect and increase funding for geroscience research across NIA, NIH, and ARPA-H to make strides against age-related illnesses.

1 week ago 0 0 0 0
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STOMP The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

ARPA-H has announced a new program that aims to detect, understand the health impacts of, and remove microplastics from the body: arpa-h.gov/explore-fund...

2 weeks ago 0 0 0 0
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The economic value of targeting aging - Nature Aging An economic analysis suggests that targeting aging offers potentially larger economic gains than eradicating individual diseases. Slowing aging to increase life expectancy by 1 year is worth US$38 tri...

Here's an example of a research paper that examines the question of increasing healthy life expectancy: www.nature.com/articles/s43...

For additional reading, there have been various papers on something called the "longevity dividend".

2 weeks ago 2 0 0 0
Flyer for the Oklahoma Nathan Shock Center of Excellence in Aging Research announcing “Translational Pilot Awards.” The flyer explains that the awards support translational studies using human biosamples or animal models relevant to age-related disease. It lists available cores (CRISPR Whole-Genome Screening, Genomic Sciences, Geroscience Redox Biology, and Multiplexing Protein Analysis), includes a link to apply, and notes funding amounts of $5,000–$20,000. It highlights that awards support early-stage and senior investigators starting aging or geroscience research. Key dates: submission deadline June 1, 2026, and funding period July 1, 2026 to June 30, 2027. A QR code is shown for more information.

Flyer for the Oklahoma Nathan Shock Center of Excellence in Aging Research announcing “Translational Pilot Awards.” The flyer explains that the awards support translational studies using human biosamples or animal models relevant to age-related disease. It lists available cores (CRISPR Whole-Genome Screening, Genomic Sciences, Geroscience Redox Biology, and Multiplexing Protein Analysis), includes a link to apply, and notes funding amounts of $5,000–$20,000. It highlights that awards support early-stage and senior investigators starting aging or geroscience research. Key dates: submission deadline June 1, 2026, and funding period July 1, 2026 to June 30, 2027. A QR code is shown for more information.

The Oklahoma Nathan Shock Center Translational Pilot Awards open this Wednesday, April 1!
🔗 For more information: oklahomanathanshockcenteronaging.org/translationa...
#Geroscience

3 weeks ago 1 1 0 1

Submissions for the OKNSC Translational Pilot Awards are now open!

2 weeks ago 1 1 0 1
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Nevada Regulators Fine Peptide Providers at Anti-Aging Festival Where Two Women Became Critically Ill Three individuals, along with the group accused of supplying the peptides, were fined between $5,000 and $10,000 for their involvement in an incident at the Revolution Against Aging and Death Festival...

There is scant evidence to justify claims made by promoters behind the peptide craze. People should also know there are risks to taking these injections. Thankfully Nevada regulators helped hold some of these promoters accountable for violating state law:
www.propublica.org/article/raad...

1 month ago 1 1 0 0

@trahan.house.gov Your support for ARPA-H is commendable, and I urge you also to act to protect researchers supported by NIA grants. Even if Congress restores funding levels, research can be sabotaged by low grant approval rates. Your support for NIA research is urgently needed.

1 month ago 0 0 0 0

Thank you for your support of ARPA-H and for your participation in the Longevity Science Caucus. The PROSPR and FRONT programs in ARPA-H are especially inspiring and great examples of bold research within geroscience.

1 month ago 0 0 0 0
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U.S. agency will devote $144 million to studies that slow aging, extend quality of life ARPA-H will “build the train tracks” for first large clinical studies of aging interventions

ARPA-H will “build the train tracks” for the first large clinical studies of aging interventions. https://scim.ag/4dcPEJj

1 month ago 20 4 2 0
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Advancing Longevity Trials: Lessons from mTOR-Targeting Interventions What two decades of trials can teach us about translating rapamycin to human aging.

An informative overview on research and trials of mTOR-targeting interventions by Nicolas di Leo with a mention of @lamminglab.bsky.social, @arpa-h.bsky.social, and many others :
norngroup.substack.com/p/advancing-...

1 month ago 1 0 0 0
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Support the Human Ageing Genomic Resources Help Joao Pedro Magalhaes raise money to support University of Birmingham

🚨 The Human Ageing Genomic Resources Are at Risk

For over 20 years, our Human Ageing Genomic Resources (HAGR) have supported ageing and longevity research.

We are raising funds to secure their continuity while we pursue long-term funding.

www.justgiving.com/page/human-a...

1 month ago 5 5 0 1
AFAR Board Member in the News: Nir Barzilai, MD, elected to the Association of American Physicians (AAP) - American Federation for Aging Research AFAR is pleased to announce that Board Member Nir Barzilai, MD, has been elected to the Association of American Physicians (AAP), one of the most

Nir Barzilai was elected to the Association of American Physicians:
www.afar.org/news/afar-bo...

1 month ago 1 0 0 0
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Research teams to add more healthy years to Americans’ lives as they age The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

@liccardo.house.gov Congratulations to Stanford University in your district! They are one of the awardees in the @arpa-h.bsky.social PROSPR program. This is an important development for the Longevity Science Caucus. Thanks for being a member and supporting geroscience.

arpa-h.gov/news-and-eve...

1 month ago 0 0 0 0
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Christin Glorioso also wrote her thoughts on the trial, and she mentions you too: drglorioso.substack.com/p/the-new-yo...

1 month ago 0 0 0 0
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Most of us don’t just want longer lives, but more years of good health. PROSPR awardees are spotting early signs that health is slipping, building systems for aging clinical trials & testing new drugs that could be the 1st gen drugs to extend healthy years. Meet the teams: arpa-h.gov/news-and-eve...

1 month ago 1 1 0 0
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This startup raised $250 million to help dogs live longer Longevity Fund-backed Loyal is working toward FDA approval of a drug that could help dogs live longer, healthier lives.

You might be interested in following Loyal's clinical trial to increase canine healthy lifespan: www.fastcompany.com/91490365/loy...

Their blog is also interesting reading: loyal.com/blog

2 months ago 3 0 1 0

🚨 BIOGAMI Proposers' Day Registration is closing soon – sign up by Feb. 18 at 5pm ET for in-person attendance, or by Feb. 19 at noon ET for virtual attendance. arpa-h.gov/explore-fund...

2 months ago 1 1 0 0

I wonder if the term "geroscience" would be better than "longevity." "Longevity" has been adopted by quacks and grifters and is also used in many different ways. "Geroscience" might be reserved for more narrow use of research on aging biology and associated clinical trials.

2 months ago 0 0 1 0
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Silver Linings Generated by create next app

This is encouraging and shows why medical research targeting aging biology to impact age-related health decline is only growing in importance. Tyler Cowen, Richard Evans, and other economists recently helped produced this interactive on ROI of R&D in Geroscience: silverlinings.bio?chapter=abou...

2 months ago 0 0 0 0
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Life Biosciences Announces FDA Clearance of IND Application for ER-100 in Optic Neuropathies IND clearance marks the first ever cellular rejuvenation therapy using partial epigenetic reprogramming to reach human clinical trials BOSTON, January 28, 2026 – Life Biosciences, Inc., (“Life Bio”) a...

@lifebiosciences.bsky.social, founded by @davidsinclairphd.bsky.social & Tristan Edwards, helmed by CEO Jerry McLaughlin, has received @fda.gov IND clearance for cellular rejuvenation using partial epigenetic reprogramming in optic neuropathies. I'm so proud: www.lifebiosciences.com/life-bioscie...

2 months ago 1 1 0 0
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Program Manager Andrew Brack also ran his lab at UCSF!

2 months ago 0 0 0 0
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ARDD This is the channel for the Aging Research and Drug Discovery meeting (www.agingpharma.org). We reserve the right to remove derogatory, personal and/or non-scientific comments.

Aging Research and Drug Discovery (ARDD) has begun uploading video lectures from its Aug 2025 conference: www.youtube.com/@ardd3628/vi...

2 months ago 1 0 0 0
BioAge Announces Indication Expansion for Oral NLRP3 Inhibitor BGE-102, with Plans to Initiate Phase 1b/2a Proof-of-Concept Clinical Trial in Patients with Diabetic Macular Edema in Mid-2026 | Tue, 01... BGE-102 has the potential for therapeutic retinal exposure with oral delivery, reducing treatment burden in ocular indications currently treated with intravitreal therapies Growing preclinical and cli...

BioAge Labs provides on update on its 2026 clinical plans for oral NLRP3 inhibitor:
ir.bioagelabs.com/news-release...

2 months ago 1 0 0 0

Too true. HHS is the largest health organization in the world and should be headed by someone who adheres to science-based medicine rather than quackery and conspiracy-theory thinking.

2 months ago 1 0 0 0

PA indeed has an impressive biotech/pharma scene. There are high-profile startups/firms with a focus on age-related illness, like LyGenesis aiming for organ regeneration and Annovis Bio targeting neurodegeneration. Both are running clinical trials. Fostering these ecosystems is critically important.

3 months ago 0 0 0 0

Call on your house representatives to support a FY2026 budget bill that would preserve funding for NIH at the Senate Appropriations Committee approved level of $48.7B and adopt Senate language prohibiting a cap on indirect costs and limiting multi-year funded grants to levels consistent with FY2024

3 months ago 6 5 0 0
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We absolutely do know that Waymos are safer than human drivers What Bloomberg got very wrong about self-driving cars

FYI - Kelsey Piper describes around the middle of her section "Doing the math" what she believes are two math errors in your article: www.theargumentmag.com/p/we-absolut...

3 months ago 3 0 1 0
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