Come and read our latest study from the @milnerevolution.bsky.social explores genome evolution 🧬 and lifespan 🐋 across mammals! now out in Scientific Reports with @springernature.com Read 📖 here: www.nature.com/articles/s41....
Huge thanks to @uniofbath.bsky.social and UNAM for the support!

Genomic insights into extended-spectrum β-lactamase- and plasmid-borne AmpC-producing Escherichia coli transmission between humans and livestock in rural Cambodia Introduction. The global spread of extended-spectrum cephalosporinase-producing Escherichia coli (producing extended-spectrum β-lactamase or plasmid-borne AmpC, hereafter ESC-Ec) is a major public hea...

New paper alert 🚨 Genomic insights into extended-spectrum β-lactamase- and plasmid-borne AmpC-producing Escherichia coli transmission between humans and livestock in rural Cambodia. Incredible effort from Ebraheem Elmarghani and others for their contributions! 👏💩🧫🦠🧬
doi.org/10.1099/jmm....

It is always such a pleasure to learn by interviewing the amazing people working to understand this world we live in.
In this conversation we talk everything from birds 🐥, dinosaurs 🦕, travels 🌎 and of course #AMR! 🦠

Tune in: bit.ly/AMRep58

Thrilled to join @uac-uu.bsky.social on The AMR Studio!🎙️Great discussion on AMR, wild birds, One Health, and of course—Campylobacter! 🦆💊🦠
A must-listen for anyone passionate about science, global health, and antibiotic resistance. Huge thanks to @evagaresp.bsky.social for an insightful discussion!🔗👇

Exploring SNP filtering strategies: the influence of strict vs soft core Phylogenetic analyses are crucial for understanding microbial evolution and infectious disease transmission. Bacterial phylogenies are often inferred from SNP alignments, with SNPs as the fundamental ...

Do you make core genome alignments for phylogenomics? Mona Taouk and I explored how including sites with some missing data (a soft core) can improve analysis, especially for large datasets.
www.microbiologyresearch.org/content/jour...
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Great to present our microbiome research today at the IMBact Seminar series in Uppsala 🇸🇪 @uuuniversity.bsky.social
Engaging questions and interest from ECRs and other researchers and very nice to see old friends too. Thanks @lionelguy.bsky.social & @evanmou.bsky.social for the invite!

Host ecology regulates interspecies recombination in bacteria of the genus Campylobacter Horizontal gene transfer can potentially merge genomes from distinct bacterial species, but isolation in different hosts creates a physical barrier to gene flow.

@evanmou.bsky.social previously identified cmeB as a gene often shared between #Campylobacter species. Link: elifesciences.org/articles/73552

Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in Campylobacter isolates from infants and poultry in the Peruvian Amazon | mBio Antimicrobial resistance in Campylobacter is a growing public health concern, driven by the rapid evolution and zoonotic transmission of resistant strains. This study focuses on mutations in the cmeAB...

AMR in #Campylobacter threatens the efficacy of oral antibiotics for treating gastrointestinal diseases in regions like Peru. Our study links resistance mutations to poultry reservoirs, underscoring the urgent need for targeted interventions. #AMR Link: journals.asm.org/doi/full/10....

Global, source, sequence type, and time distribution of the high-resistance cmeB gene from Campylobacter strains in the PubMLST database. Percentage of Campylobacter strains from various countries around the world with the RE-cmeB high-resistance gene (minimum 40 genomes).

We find more examples of these high resistance in global datasets - particularly in LMICs, and predominantly in lineages associated with chicken production (credit to @pubmlst.org)

Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in Campylobacter isolates from infants and poultry in the Peruvian Amazon | mBio Antimicrobial resistance in Campylobacter is a growing public health concern, driven by the rapid evolution and zoonotic transmission of resistant strains. This study focuses on mutations in the cmeAB...

🚨 A twixmas surprise, our final paper of 2024:
Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in #Campylobacter 🧵

Link: journals.asm.org/doi/full/10....

#Microbiology #MicroSky #AMR

Geographical variation in the incidence of colorectal cancer and urinary tract cancer is associated with population exposure to colibactin-producing Escherichia coli Biomedical research has implicated the bacterial metabolite colibactin as a causal risk factor for several cancer types, in particular, colorectal can…

New paper:

We show that population exposure to colibactin producing E. coli lineages ST95 and ST73 largely explains global variation in colorectal cancer incidence. Same STs are also major causes of UTIs and may be similarly involved in urinary tract cancers.

www.sciencedirect.com/science/arti...

Excited to make my first post here! What an incredible experience to visit Japan for the first time during such beautiful autumn weather!
I had the privilege of giving a talk at the “Japangenome” SMBE satellite workshop in Tokyo! Grateful for the opportunity and inspired by all the amazing science!