A @umh.es delegation attended the inauguration of the new @theneurotecheu.bsky.social space at the #UMF Cluj-Napoca, strengthening collaboration within the alliance 🧠🇪🇺
Featuring a presentation by the @neuroalc.bsky.social director, Juana Gallar 👇
in.umh-csic.es/en/una-deleg...
Today, the IN Cellular and Systems Neurobiology Scientific Department has offered a new scientific seminar featuring the presentation of PhD students Alejandro Gómez Restrepo (lab @painchannels.bsky.social) and Vicente Miralles Liborio (Lab. Ocular Neurobiology)👏👏👏
@csic.es @dicv.csic.es @umh.es
We’re pleased to announce the XII Remedios Caro Almela Prize in Developmental Neurobiology ceremony, organized by @neuroalc.bsky.social & Remedios Caro Almela Chair.
10:30 Lecture by Prof. Sonia Garel
12:00 Award ceremony
👉 in.umh-csic.es/en/entrega-d...
@college-de-france.fr @ibensens.bsky.social
🦠Un gen determina si las células de #cáncer de mama forman metástasis o permanecen ‘dormidas’
🔬El gen Prrx1 regula su potencial metastásico, según un estudio de @neuroalc.bsky.social
🔎Estas células, preparadas para formar metástasis, están presentes en el tumor primario
➡️ http://tiny.cc/o242101
El @neuroalc.bsky.social celebrará el próximo 23 de abril un acto de homenaje al Prof. Jorge Manzanares, abierto al público.
Un encuentro para poner en valor su extraordinaria trayectoria científica, docente y humana en neurofarmacología.
Más información 👇
in.umh-csic.es/en/acto-de-h...
Tumor de mama en ratón con células cancerosas (rosa)./ IN (CSIC-UMH)
🧬Un gen determina si las células de cáncer de mama forman metástasis o permanecen dormidas
🔬Un estudio en ratones de @neuroalc.bsky.social identifica el gen Prrx1 como regulador del potencial metastásico en el cáncer de mama
@csic.es @umh.es
delegacion.comunitatvalenciana.csic.es/un-gen-deter...
You can read the full paper here 👇 (7)
doi.org/10.1038/s414...
@csic.es @dicv.csic.es @umh.es @ageinves.bsky.social @cienciagob.bsky.social @khalilkassyoussef.bsky.social @bertalsl.bsky.social #AECC #ContraelCancerES #MDAndersonES
These findings provide a new perspective on the origin of metastatic potential and suggest new avenues for preventing tumor cells from entering this particularly dangerous state (6/7)
Analyses of breast cancer patient samples reveal similar patterns, suggesting that this Prrx1 dependent state may identify tumors at higher risk of forming metastases and refine clinical stratification (5/7)
Cells with intermediate Prrx1 levels are the most competent to form metastases. They maintain invasive behavior while sustaining proliferation after dissemination. In contrast, high Prrx1 levels induce dormancy, and low levels impair dissemination from the primary tumor (4/7)
A central finding is that metastatic capacity is controlled by the transcription factor Prrx1, whose effects depend on its expression levels. Prrx1 determines whether cancer cells remain dormant, fail to disseminate, or reach a state that enables metastatic growth (3/7)
📹@ruljcz.bsky.social
Combining single cell transcriptomic and epigenomic analyses, genetic mouse models and patient samples, the study identifies a subpopulation of cells at the invasive edge of breast tumors with the molecular features associated with future metastatic behavior (2/7)
#CancerResearch
A new study led by @nietoangela.bsky.social lab at @neuroalc.bsky.social is out in Nature Communications🙌. Researchers show that cancer cells acquire metastatic potential while in the primary tumor, well before reaching distant organs (1/7)
More info 👇
in.umh-csic.es/en/articulos...
Enhorabuena a @nietoangela.bsky.social por su inclusión en la lista Forbes España de los 100 más creativos en los negocios 2026. Este reconocimiento destaca el impacto y la proyección social de su trayectoria👏
@raciencias.bsky.social @csic.es @dicv.csic.es @umh.es 👇
forbes.es/lista-forbes...
📰 Conoce la actualidad y la agenda de los centros @csic.es en la Comunitat Valenciana en el boletín #SemanaCSIC:
delegacion.comunitatvalenciana.csic.es/boletin-sema...
@comunicacion.iats.csic.es @i2sysbio.es @itq-csicupv.bsky.social @ibmcp.bsky.social @iatacsic.bsky.social
@neuroalc.bsky.social
Today, we had the pleasure of hosting Dr. Benedikt Berninger, from Centre for Developmental Neurobiology- King's College, at our #SeminarsIN with his talk: Engineering new interneurons through in vivo glia-to-neuron lineage conversion.
A fantastic lecture, thank you! 👏
@guillelbendito.bsky.social
We have the pleasure of welcoming Dr Benedikt Berninger, from the Centre for Developmental Neurobiology-King’s College, next Friday at #SeminarsIN 🙌
He's an expert in neuronal reprogramming and brain plasticity, pioneering work on glia-to-neuron conversion. Don’t miss it!
⏳ Good news! Deadline extended to May 1st
Join leading researchers exploring how mechanical forces shape development and physiology
👉 mechano2026.umh.es
@csic.es @dicv.csic.es @umh.es @painchannels.bsky.social @borrell-lab.bsky.social @embo.org @naniontech.bsky.social @3brainag.bsky.social
Today, the IN Developmental Neurobiology Scientific Department has offered a new scientific seminar featuring the presentation of PhD student Isabel Pérez Ferrer (Lab. @eloisaherrera.bsky.social) and researcher Martina Riva (Lab. J. A. Moreno-Bravo) 👏👏
@csic.es @dicv.csic.es @umh.es
🧠Un circuito cerebral conecta ambos hemisferios para coordinar la #memoria espacial
🔬Un estudio en ratones de @neuroalc.bsky.social describe un ‘puente’ de neuronas entre los hemisferios del #hipocampo
🔎Es esencial para la orientación espacial y la toma de decisiones
👉http://tiny.cc/t0s1101
Hipocampos de ratón con las conexiones neuronales (verde) que conectan ambos hemisferios. / IN-CSIC-UMH
🧠🐁El @neuroalc.bsky.social describe un 'puente' entre los hemisferios del hipocampo en ratones esencial para la orientación espacial. Esta conexión se altera en la esquizofrenia y ayudaría a entender los déficits cognitivos.
@csic.es @umh.es
delegacion.comunitatvalenciana.csic.es/un-circuito-...
You can read the full paper here 👇
doi.org/10.1016/j.ce...
@csic.es @dicv.csic.es @umh.es @erc.europa.eu @ageinves.bsky.social @cienciagob.bsky.social @cnb-csic.bsky.social
The circuit is also altered in a mouse model of the 22q11.2 deletion, linked to schizophrenia, suggesting a mechanism behind cognitive deficits.
In this video, @neuroalc.bsky.social researcher Félix Leroy @leroyfelix.bsky.social explains the main findings 👇
youtu.be/kSnwA9MR3AI
Using optogenetics, researchers selectively disrupted this circuit in mice and found:
🧠 Impaired spatial memory
🧭 Difficulties in navigation
❗ No changes in anxiety or object recognition
This highlights its specific role in spatial cognition.
The study reveals a previously unknown connection between the two hippocampal hemispheres: neurons from the right CA1 project to the left subiculum, forming a “bridge” essential for spatial orientation and memory-based decisions.
📷@cp-cellreports.bsky.social
🔥A new study led by @leroyfelix.bsky.social lab at @neuroalc.bsky.social is published in @cp-cellreports.bsky.social 🔝
Researchers identify a key brain circuit for spatial memory
More info 👇
in.umh-csic.es/en/articulos...
Excited to share our new preprint from the lab!
@desantislab.bsky.social @silviadesantis.bsky.social @neuroalc.bsky.social
📄 Preprint: biorxiv.org/content/10.6...
How brain networks counteract structural decline during aging — and why does sex matter?
A thread! 👇
The meeting featured 8 scientific sessions, 2 posters sessions, 3 plenary lectures, and a tribute to Antonio García-Bellido, an international leader in genetics and developmental biology, with contributions from leading national and international scientists 🔝
@csic.es @dicv.csic.es @umh.es
The @neuroalc.bsky.social has hosted the II @drosospain.bsky.social Conference, bringing together over 100 researchers to share the latest advances using the fruit fly as a model organism 🧬🪰
Read more 👇
in.umh-csic.es/en/el-instit...
@csic.es @dicv.csic.es @umh.es
@cbm-csic-uam.bsky.social
The Board of Governors of @theneurotecheu.bsky.social met to define the roadmap for the final 2 years of its second phase, helping advance a European ecosystem in neurotechnology.
With Juana Gallar, Director of @neuroalc.bsky.social, in attendance. Read more 👇 neurotecheu.umh.es/en/2026/04/1...
