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Posts by Débora Y C Brandt

Hi, cool work! I found it from the title, but the link is to a different paper...

5 days ago 2 0 1 0
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Welcome to RustQC Fast quality control tools for sequencing data, written in Rust.

Super excited to be launching two things today: #RustQC 🦀🧬 and rewrites.bio 🚀

I used AI to rewrite 15 RNA-seq QC tools into a single Rust binary (I've never written any Rust). It ended up being over 60x faster. Here's the story 🧵

seqeralabs.github.io/RustQC/

2 weeks ago 84 36 3 4

Our paper is on the cover of @currentbiology.bsky.social : a strawberry poison frog with the most common color morph, living up to its common name 🍓. In this issue, we uncover the genetic basis of color variation in frogs from Bocas del Toro, where blue, green, yellow, orange, and red morphs occur

4 weeks ago 81 27 2 3
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Fantastic seminar from @deboraycb.bsky.social discussing some of the challenges and limitations of detecting balancing selection from genomic data and her ongoing work on developing a new ARG-based approach.

See preprint here: www.biorxiv.org/content/10.6....

1 week ago 12 5 0 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

Spread the word! UChicago BSD is currently searching for an instructional professor (open rank) to help develop and support graduate training in quantitative biology at UChicago. This is an Instructional Professor position (open rank). apply.interfolio.com/183517.

1 week ago 24 39 2 1
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Join our department (GEE) as a fellow - Research Career Development Fellowships Program Call: tinyurl.com/2sfpyhsz

GEE invites #ECRs who wish to be sponsored to apply for external fellowships to establish an independent research group. @ucllifesciences.bsky.social

More info: tinyurl.com/mtwhwzjj

1 week ago 9 11 1 0
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Registration - SMBE 2026 - Copenhagen Denmark SMBE 2026 Registration Days Hours Minutes Seconds Registration is open REGISTRATION for onsite or Virtual attendance SMBE Membership – If you are an active member of the SMBE society you can  register for SMBE with the benefit of the discounts shown below. Sign up for or activate your SMBE membership here. Danish VAT: 0% – […]

Reminder: Early bird registration for SMBE 2026 ends March 31. Join us in Copenhagen from June 28-July 2 for top speakers and diverse topics. Register here: www.smbe2026.org/registration/ #conference

4 weeks ago 3 1 0 0
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#154 O mal-estar da escrita científica

Escrever dói! 📝 Nesse novo ep falamos sobre o sofrimento na escrita acadêmica. Entender o significado da frase: “Não escrevo pra falar o que eu sei, escrevo pra descobrir o que eu tenho a dizer“. Dá o play e passa pra alguém que está escrevendo nesse momento. ✍️

open.spotify.com/episode/70zk...

1 month ago 0 1 0 0
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#154 O mal-estar da escrita científica

Obrigada @alociencia.bsky.social! Veio num momento ideal pra mim ❤️
open.spotify.com/episode/70zk...

1 month ago 1 0 1 0
A digital CAPTCHA verification window titled "Select all squares with PIPES" against a plain white background. The window contains a 3×3 grid of numbered squares, mixing literal hardware, smoking pipes, and programming syntax.

A digital CAPTCHA verification window titled "Select all squares with PIPES" against a plain white background. The window contains a 3×3 grid of numbered squares, mixing literal hardware, smoking pipes, and programming syntax.

These captchas just keep getting harder #rstats

1 month ago 625 142 8 2
UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Job alert: open position for a Professor or Associate Professor of Computational Genomics in Health and Disease at University College London.

Based in the Department of Genetics, Evolution and Environment of UCL, and UGI, and funded by the UCL Health Strategy.

www.ucl.ac.uk/work-at-ucl/... 🧪

1 month ago 14 26 1 4
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An AI Agent Published a Hit Piece on Me Summary: An AI agent of unknown ownership autonomously wrote and published a personalized hit piece about me after I rejected its code, attempting to damage my reputation and shame me into acceptin…

AI agent goes nuts on open source maintainer after having its pull request denied. This is a pretty insane story. Open source development as we've been used to for the last few decades is likely over. 1/
theshamblog.com/an-ai-agent-...

2 months ago 60 39 5 9

anyone know if there is childcare at @official-smbe.bsky.social 2026 this year? #SMBE2026

2 months ago 2 5 2 0
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Mitonuclear interactions and early-life diet shape adult nutritional behaviour Abstract. Mitochondrial function relies on close coordination between the mitochondrial and nuclear genomes. Disruption to this coordination—via mitonuclea

RESEARCH ARTICLE:

Early diet leaves a lasting mark! Mismatched mitochondrial + nuclear genes slow fly development & shift adult food choices. G×E shape metabolism & behaviour:

doi.org/10.1093/jeb/...

@stefanobettinazzi.bsky.social et al. (2025)
@fcamus.bsky.social
@dk-dowling.bsky.social

2 months ago 3 2 0 0
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A new preprint from the lab, with postdoc @deboraycb.bsky.social and collaborators @aidaandres.bsky.social and Tim Connallon:

“Characterising the detectable and invisible fractions of genomic loci under balancing selection”
www.biorxiv.org/content/10.6...

3 months ago 26 18 1 2

Balancing selection maintains some remarkable biological diversity, but detecting it from genomic data alone can be tricky. This may bias our view of its true prevalence. We investigated what makes balancing selection more or less detectable in genomic scans. + in thread & preprint!

3 months ago 11 5 0 0

Balancing selection alert!! 🧬🧪

New preprint where we try to quantify how likely (or rather, unlikely) it is for balancing selection to maintain stable polymorphism, and how easy (or rather, challenging) it is to identify its signatures in genomes.

#Popgen #MolecularEvolution #EvoBio #Science

3 months ago 26 9 0 0

Balancing selection maintains some remarkable biological diversity, but detecting it from genomic data alone can be tricky. This may bias our view of its true prevalence. We investigated what makes balancing selection more or less detectable in genomic scans. + in thread & preprint!

3 months ago 11 5 0 0
Remember to submit your abstract and your award application for SMBE 2026 in Copenhagen by February 3.

Remember to submit your abstract and your award application for SMBE 2026 in Copenhagen by February 3.

❗Just two weeks to go!

Please remember to submit your abstract and award application for SMBE 2026 in Copenhagen by February 3.

📨 Abstract submission & Award applications
smbe2026.org/abstracts

📋 Programme details
smbe2026.org/programme

#SMBE2026

3 months ago 8 12 0 1
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Robustness of Ancestral Recombination Graph Inference Tools to Phasing Errors Ancestral Recombination Graphs (ARGs) are fundamental population genetic structures that encode the genealogical history of a sample of haplotypes along the genome. They have recently received substan...

We are excited to share our recent work on the surprising robustness of Ancestral Recombination Graph (ARG) inference tools to computational phasing errors, now available on BioRxiv: biorxiv.org/content/10.1....
This work is co-advised by @yundeng.bsky.social and Rasmus Nielsen.
1/7

4 months ago 54 24 2 1

Uau parabéns!!!

5 months ago 1 0 0 0

And we are LIVE! Join us for Day 1️⃣
www.youtube.com/watch?v=rP0X...

#conference #genomics #ERGA @biogeneurope.bsky.social

5 months ago 1 2 0 1
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HHMI adopts Plan U journals.plos.org/plosbiology/...

6 months ago 150 69 9 16
Um pequeno pássaro azul brilhante com pernas e pés amarelos brilhantes está empoleirado em um galho. Ele tem uma mancha preta no peito e no abdômen. O fundo é verde borrado.
Atenção: O alt da imagem foi gerado automaticamente.

Um pequeno pássaro azul brilhante com pernas e pés amarelos brilhantes está empoleirado em um galho. Ele tem uma mancha preta no peito e no abdômen. O fundo é verde borrado. Atenção: O alt da imagem foi gerado automaticamente.

🇧🇷Saí-de-perna-amarela
🌎Cyanerpes caeruleus
Conservação:Pouco Preocupante

A saí-de-perna-amarela é um Passeriforme da família Thraupidae.


📷 Ester Ramirez

7 months ago 162 16 2 10
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Important heads up! This is crazy

7 months ago 0 3 0 0
depois de dois anos da primeira tira, completando agora com o personagem abrindo a latinha de cerveja que deve tá quente já mas fodase, bolsonaro condenado cuida pai sextou

depois de dois anos da primeira tira, completando agora com o personagem abrindo a latinha de cerveja que deve tá quente já mas fodase, bolsonaro condenado cuida pai sextou

PODE JÁ!!

7 months ago 10202 5508 174 638

Jasmin Rees PhD chapter as a paper just out at the AJHG @ajhgnews.bsky.social, with Sergi Castellano, who first envisioned the study. Jas investigated signatures of human local genetic adaptation in hundreds of micronutrient-associated genes.

7 months ago 25 16 1 1
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Robust and accurate Bayesian inference of genome-wide genealogies for hundreds of genomes - Nature Genetics SINGER is a method for creating ancestral recombination graphs to understand the genealogical history of genomes. The method has increased speed, and thus scalability, without sacrificing accuracy.

SINGER, our ARG inference method, is finally published and freely available online:

doi.org/10.1038/s415...

It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...

7 months ago 102 52 1 3
SMBE2026 - Call for Symposia Proposals

SMBE2026 - Call for Symposia Proposals

📢 The Call for Symposia for SMBE2026 is now open. We warmly invite you to submit a symposium proposal and help shape the scientific content of our annual meeting.

🗓️ Key dates
Call for symposia: Sep. 1 - Oct. 15
Announcement of accepted symposia: Nov. 3

More information: smbe2026.org/symposia

7 months ago 14 12 2 2

Excited to share our new preprint🙌
It's the first human WGS study in Sudan. We uncover one of the strongest selection signals to date, pointing to post-admixture adaptation to malaria in Copts. Huge thanks to all co-authors. @aidaandres.bsky.social @jgarcia-cal.bsky.social @ebosch1972.bsky.social

7 months ago 21 13 2 0