Meta just paid the lowest effective federal tax rate in its history.
Thanks to tax breaks and loopholes, it avoided $13.7B in 2025 federal income taxes.
But now it's planning to lay off 10% of its global workforce (8,000 people) by May 20 — with more job cuts later this year.
Trickle down hoax.
Which way best defines the optimal deep brain stimulation target in #Parkinsons? x-y-z coordinates? sweet spots? fiber tracts? whole-brain networks?
@patriciazvarova.bsky.social has just answered this question: All of them.
New study out now in AoN: onlinelibrary.wiley.com/doi/epdf/10....
@macshine.bsky.social talks with Mario Senden about his new project using AI-driven bibliometrics to map the structural organization of neuroscience across 25 years. The field it reveals is at once thriving and theoretically adrift. #neuroskyence
www.thetransmitter.org/methods/what...
In a rare show of unity, both R and D US lawmakers agree: the scientific publishing industry needs reform.
Lawmakers are worried about the literature being flooded with 'AI slop' and the high open-access fees that some publishers charge.
Read more @nature.com on this week's House Science hearing
The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states!
Out today in Nature: rdcu.be/fdC2A
@uclbrainscience.bsky.social
White matter pathways mediating dorsolateral prefrontal TMS therapy for depression
New @natneuro.nature.com paper led by Caio Seguin, Robin Cash, and Andrew Zalesky.
We map (indirect) pathways from DLPFC to SGC and link individual variation with response efficacy.
www.nature.com/articles/s41...
This looks like a significant discovery from Doris Tao's lab:
Rapid concerted switching of the neural code in the inferotemporal cortex
@nature.com
"..our findings indicate that there is a previously unknown mechanism for neural representation:.."
www.nature.com/articles/s41...
Since Viktor Orbán’s approach to governance in Hungary was cited by the Heritage Foundation as their blueprint for #Project2025 (kettering.org/the-global-d...) it seems like a good time to re-up this piece in Aug '24 piece in @thebulletin.org: thebulletin.org/2024/08/proj...
Rotavirus is the largest killer of children in the world under 5.
There is a vaccine.
Tx also consists of rehydration w/simple oral electrolytes to replenish fluids, minerals, and electrolytes.
USAID distributed all of that saving lives across the world.
Trump killed it, and is killing them.
Semantic Network of OECS articles.
Reminder! The Open Encyclopedia of Cognitive Science (OECS) hosts summaries of what we know vs don't about a host of fascinating issues. All freely available.
What a terrific alternative to doomscrolling: learning about (e.g.) The Mind-Body problem, Delusion, or Free Will.
oecs.mit.edu
GAME CHANGER: Montana just found the "exit ramp" to kill Citizens United. They aren't waiting for the Supreme Court—they’re going around them. 74% of voters are on board and corporate lawyers are PANICKING. This is how we win. 🏔️💸 www.dworkinsubstack.com/p/army-secre...
Absolutely remarkable statement from Pope Leo today.
One for the history books
www.theguardian.com/world/2026/a...
Science is good. We should fund it.
We're excited to share our new study on decoding brain activity in participants with post-stroke aphasia! We think this is an important step towards cognitive brain-computer interfaces for patients with language disorders
www.biorxiv.org/content/10.6...
1/8
Nice article about our @CIHR_IRSC funded research in the New York Times today @westernu.ca www.nytimes.com/2026/04/09/m...
Don’t forget to vote, I’m running for OHBM chair! 🧠
We develop a new TMS targeting algorithm and test it in an open label trial in a treatment-resistant depression population with high comorbidities. Preprints by @rubykong92.bsky.social Phern-Chern Tor
1. doi.org/10.1101/2025...
2. doi.org/10.64898/202...
Our new approach ...
Our new paper on brain networks engaged during imagining is out now in Neuron!
Here is a download link (free for 50 days):
authors.elsevier.com/c/1msNE3BtfH...
Congratulations to Nate Anderson for leading this work @rementurus.bsky.social
🧵
This is not a 'masculinity crisis', it's a misogyny crisis. This is not a problem with 'masculinity'-- millions of men model positive masculinity every day. This is a problem of male violence. Stop calling it 'masculinity'.
www.theguardian.com/education/20...
Yes, I already shared this. Yes, I am unashamedly sharing it again. This image means so much to me personally as a #WomenInSTEM and space scientist 🔭🧪 🌗🪐🌎. Christina Koch once worked at GSFC, where I now work, and was at APL, where I worked before, when selected as an Astronaut!
Hitler and the Nazi Party equated themselves with Christianity -- the result was Germany becoming one of the most atheist countries after the war.
It is in Christianity's own interest to rebuff Trump's attempts to co-opt Christianity to legitimize his immoral behavior.
New York Times article exploring the scientific brain drain to Europe.
[Gift link]
www.nytimes.com/2026/04/04/b...
Salt Lake City seeing this
The Edmonds-based travel writer and TV personality says: “A new tax on fat paychecks like mine was just signed into law in my home state — and I like it.”
“People like stories and people resonate to stories,” she said on Chalk Talk, a podcast published by MIT OpenCourseWare. Her first lecture in her introductory undergraduate course starts with a personal story about a friend who collapsed on the floor of her house – and subsequently proved to have a benign brain tumor in an area that Kanwisher’s lab had been studying. Viewer numbers confirm Kanwisher’s sense of storytelling: that first lecture video broke MIT Open Courseware’s 20-year record for the most views, with more than 10 million views.
Three cheers for @nancykanwisher.bsky.social's remarkable science outreach! Her lectures have millions of views (including 10 million for one lecture alone, breaking an MIT record).
She's even shaved her head for outreach 💙.
norwegianscitechnews.com/2024/08/find...
The SCORE investigation of repeatability and credibility is a lot. There are a few ways to get your head around it.
1: The Nature collection includes 3 papers from SCORE, an amazing paper from @i4replication.bsky.social and several commentaries about the work.
www.nature.com/collections/...
1/
🧠 Focused ultrasound changes emotional processing 🔊
In a new study published in Neuron today, we stimulated the human amygdala using transcranial ultrasound stimulation (TUS) and show it plays a causal role in detecting and resolving emotional ambiguity.
How do we define "good" fMRI data? Especially with resting state, there are circularity risks if we evaluate data quality as showing the networks we expect to see. Javier Gonzalez-Castillo (& me & others) developed pBOLD, a new metric that uses multi-echo info. www.biorxiv.org/content/10.6... 1/8
SCORE, a collaboration of 865 researchers, is now released as three papers in Nature, six preprints, and a lot of data (cos.io/score/). SCORE examined repeatability of findings from the social-behavioral sciences and tested whether human and automated methods could predict replicability.
