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Posts by Jakob Macke

sbi v.0.26.1 is out 🎉. We initially planned this release for January, but then the Grenoble Hackathon and GSoC applications happened. Now we have three new methods, better neural nets, cleaner internals, better docs, and 9 new contributors 🤗.

Highlights below 🧵

1 week ago 9 4 1 0

We’re launching a new AI Methods & Software Hub in the ML cluster and are looking for a Director to build and lead it!

Shape how ML/AI and software drive scientific discovery—in close collaboration with AI and domain scientists—within an extremely vibrant and collaborative ecosystem!

3 weeks ago 10 6 0 0
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🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social

We gave a worm brain control of a fly body and it walked

What did we learn? Nothing, other than deep reinforcement learning is effective

We call it the digital sphinx

www.biorxiv.org/content/10.6...

4 weeks ago 397 147 9 27
bar chart, different cities in Germany, sorted by number of excellence clusters per 100.000 citizens. Tübingen leads with 5.78, second is Jena with 1.82

bar chart, different cities in Germany, sorted by number of excellence clusters per 100.000 citizens. Tübingen leads with 5.78, second is Jena with 1.82

How academic are different cities in Germany? The one definite ranking. #exinit @unituebingen.bsky.social

4 weeks ago 7 2 1 0
Coordinator (m/f/d, E13 TV-L, 75%)

🚨 We're hiring: Research Coordinator for CRC Robust Vision
@unituebingen.bsky.social

Take a leading role in our DFG funded consortium in neuroscience, ML & CV

MSc/PhD + science mgmt. Apply by Mar 15 👇 join our team w/ @jakhmack.bsky.social @bethgelab.bsky.social

uni-tuebingen.de/en/universit...

2 months ago 11 7 0 0
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Hiring now!
📢 The CRC 1233 Robust Vision consortium at @unituebingen.bsky.social is looking for a Research Coordinator to lead science management, support project execution, and help steer our interdisciplinary research in neuroscience, machine learning and computer vision.

2 months ago 7 4 1 0
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The Brain Prize Course - Computational and Theoretical Neuroscience - CAJAL […]

A special year for the Cajal Course in Computational Neuroscience: the BRAIN Prize winners Haim Sompolinsky and Larry Abbott will join us as keynote speakers. And we will bring you the same great roster of instructors as every year. Applications are now open! cajal-training.org/on-site/comp...

2 months ago 27 11 1 1
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SBI Hackathon Grenoble is a wrap! 🎉

35 researchers and a great hybrid format of 1.5 days of tutorials + 1.5 days of applied hackathon. Many went from “having heard of sbi” to applying full SBI workflows to their own research projects.

🧵👇

2 months ago 16 3 2 1
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Happy 2026 everyone! Two freshly minted PhDs 🧑‍🎓emerged from our lab at the end of last year.
We congratulate Dr Julius Vetter (@vetterj.bsky.social) and Dr Guy Moss (@gmoss13.bsky.social)! Here seen celebrating with the lab 🎳. 1/3

3 months ago 18 3 1 0
Tübingen AI Research Building, where the Cluster of Excellence "Machine Learning" is based.

Tübingen AI Research Building, where the Cluster of Excellence "Machine Learning" is based.

📢We’re hiring: W3-Professorship in Machine Learning in Physics @unituebingen.bsky.social! What we’re looking for: Established research profile in a core area of #physics (condensedmatter, quantum or theoretical particle physics), strong track record in research questions related to #ML and/or #AI.

4 months ago 6 10 1 1

Oops, meant this link: erc.europa.eu/system/files...

4 months ago 0 0 0 1

Congrats to all the ERC COG recipients, of course especially to the 5 from @unituebingen.bsky.social, and even more so to the @ml4science.bsky.social members @tobiasuhauser.bsky.social and @andreasgeiger.bsky.social (AI assistants!)!!!

erc.europa.eu/system/files...

4 months ago 10 0 1 0

Come work with us!!!

4 months ago 12 6 0 1
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Finally got the job ad—looking for 2 PhD students to start spring next year:

www.gao-unit.com/join-us/

If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply!

I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮

4 months ago 81 51 1 5

English translation (by AI...):
Question:
How can generative AI contribute to supporting education and science? (Multiple answers possible)
Answer:
It can help in science by automatically generating new and innovative research approaches.

4 months ago 3 0 0 0
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We were asked to do an online training on 'AI awareness' by admin. I almost failed the test, as I was not aware of some of the fundamental limitations of #AI4Science.

4 months ago 7 0 1 0

Not going to NeurIPS Nor Eurips, but the lab is showing cool new work on SBI and differentiable biophysics, do check it out and talk to them (we also have open positions …)!

4 months ago 3 0 0 0
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* spatial models-- which come up in geosciences and many other applications, given, well, the geometry of the world we live in.

4 months ago 1 0 0 0

@gmoss13.bsky.social et al sending SBI to space 🚀*!!!

4 months ago 3 0 1 0

We are having a lot of fun and excitement both with fancy new AI methods and shiny fly connectomes … and those ERC euros make that possible!

4 months ago 2 0 0 0

lthough technically „has grown“ is not quite correct — we graduated, or will graduate soon, equally many brilliant PhDs ;-)

4 months ago 5 0 0 0
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AI tool for brain simulations links cellular detail to cognitive functions — MACHINE LEARNING for science For decades, brain simulations have either been largely simplified, or they could not perform cognitive tasks. A new AI tool opens possibilities to build brain simulations that can achieve both.

On our blog: For decades, brain simulations have either been largely simplified, or they could not perform cognitive tasks. #JAXLEY, a new AI tool, opens possibilities to build brain simulations that overcome both limitations: www.machinelearningforscience.de/en/jaxley-ai... #AIforScience

4 months ago 16 6 1 2

Possibly the best part of the job: The amazing students and scientists we get to work with!

4 months ago 17 0 2 0

Simulation-based inference has really become a commonly used tool for parameter inference across many fields and applications. We (finally...) got together to write a tutorial introduction and guide to (hopefully) help users get started and navigate the different methods and diagnostics!

5 months ago 38 11 1 0
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Jaxley: differentiable simulation enables large-scale training of detailed biophysical models of neural dynamics - Nature Methods Jaxley is a versatile platform for biophysical modeling in neuroscience. It allows efficiently simulating large-scale biophysical models on CPUs, GPUs and TPUs. Model parameters can be optimized with ...

I am super happy to share that our project on training biophysical models with Jaxley is now published in Nature Methods: www.nature.com/articles/s41...

5 months ago 78 16 1 3
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Great new work from the labs of @jakhmack.bsky.social and @philipp.hertie.ai! The software Jaxley enables brain simulations which both imitate the processes in the brain in detail and can solve challenging cognitive tasks. Press release of @unituebingen.bsky.social: uni-tuebingen.de/en/universit...

5 months ago 16 4 0 0

Congrats to @deismic.bsky.social and everyone for getting this out!

5 months ago 10 1 0 0
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An ion channel omnimodel for standardized biophysical neuron modelling Biophysical neuron modeling is an indispensable tool in neuroscience research, with the combination of diverse ion channel kinetics and morphologies being used to explain various single-neuron propert...

“Mapping ion channel function” doi.org/10.7554/eLif... isn’t exactly a citation slayer, but it’s still one of my favourites (& my first independent project). Today we push pt 2, where we trace code origin & unite almost all channel models in a common expression. Boom! www.biorxiv.org/content/10.1...

6 months ago 48 16 0 3

🎉 sbi participated in GSoC 2025 through @numfocus.bsky.social and it was a great success: our two students contributed major new features and substantial internal improvements: 🧵 👇

6 months ago 11 4 1 0
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Hello Frankfurt 🇩🇪 - We are excited to share the latest result from our group and collaborators at
@bernsteinneuro.bsky.social 🚀🧠 #BernsteinConference

Thanks to @brainloops.bsky.social, @ekfstiftung.bsky.social and @cherish-msca.bsky.social for supporting these projects and our scholars.

6 months ago 13 7 1 0