tRNA modification landscapes in streptococci: shared losses and clade-specific adaptations Abstract. tRNA modifications are central to bacterial translational control. Here, we integrated genetics, mass spectrometry, epitranscriptomics and compar

tRNA modification landscapes in streptococci: shared losses and clade-specific adaptations royalsocietypublishing.org/rsob/article...

The NIH has lost its scientific integrity. So we left “We can no longer lend our credibility to an organization that has lost its integrity,” write four scientists and administrators who recently resigned from the NIH.

Read why NIH colleagues resigned.
Brave writing from Sylvia Chou, Alexa Romberg, Paul Grothaus and Vani Pariyadath. 🧪
#science #standupforscience #integrity

www.statnews.com/2026/01/10/n...

Democratic governors to boycott White House dinner More than a half dozen Democrats said Donald Trump disinviting two of their colleagues is the latest example of administration's 'chaos and division.'

No way will I attend the White House dinner with this President.

I’m standing with @govwesmoore.bsky.social and @colorado.gov — and standing against Trump’s corruption and hatred.

And I’m calling on my Republican colleagues to do the same.

This part of our response essay is where I'm at. Boiling down all of politics to electoralism has been absolutely terrible for resisting rising authoritarianism.

www.bostonreview.net/forum/how-no...

it's more or less impossible to find issues that poll this badly and he's decided to make it a major, public priority www.cbsnews.com/news/ice-tru...

Screenshot of headline reading: Trump Links His Push for Greenland to Not Winning Nobel Peace Prize In a text, President Trump told Norway’s prime minister that he no longer felt obliged to “think purely of Peace” and that the U.S. needed the island for global security.

Invoke the 25th Amendment.

"Donald Trump now genuinely lives in a different reality, one in which neither grammar nor history nor the normal rules of human interaction now affect him. Also, he really is maniacally, unhealthily obsessive about the Nobel Prize."

www.theatlantic.com/ideas/2026/0...

This afternoon, I was in a meeting with Jay Bhattacharya, and I can confirm this is *exactly* what he both wants and will be doing.

THIS IS NOT HYPERBOLE.

Boston's Mayor Wu playing with Yo-Yo Ma at Symphony Hall

MAGA Nation is an account based in the EU. Dark MAGA is an account based in Thailand. Joined from UK.

MAGA Scope is an account based in Nigeria. The MAGA Beacon is an account based in South Asia.

Spetsna 007 is an account based in France, joined from Nigeria. Mary Tiles Texas is an account based in Russia.

Musk turned on a feature on X that showed country of origin.

He disabled it a couple hours later when it was revealed how many MAGA accounts aren't in the U.S.

Foreign bot disinformation machines exposed.

Seems like Twitter could have done that feature 15 years ago & we wouldn't be here today.

NEW: Epstein survivors release the most powerful PSA I have ever seen.

Make this go viral so every member of the House of Representatives sees it.

I don’t know who needs to hear this but the CDC is being eviscerated right now. America is not going to have any kind of outbreak response capacity after tonight. Americans’ health data is no longer secure. Say goodbye to federal public health in any capacity. It’s a disaster. We won’t recover.

“With your patient and rigorous work, you can act as a barrier against those who, through the ancient art of lying, seek to create divisions in order to rule by dividing,” he said. “You can also be a bulwark of civility against the quicksand of approximation and post-truth.”

tRNA-modifying enzymes in bacterial stress adaptation | Open Biology Transfer RNAs (tRNAs) and their modifications are central to bacterial translation and physiology, yet their roles in stress adaptation remain underexplored. While extensively studied in eukaryotes, a...

Happy to share our new review in Royal Society Open Biology 🎉
tRNA-modifying enzymes in bacterial stress adaptation:
How tRNA mods rewire translation under oxidative + antibiotic stress (MoTTs, moonlighting, therapy angles).
Read: doi.org/10.1098/rsob...
#RNAsky #microsky #AMR #RNAmodifications

Basic Science Is The Foundation Of Future Cures Injecting partisan politics into American basic science would be terrible for the US: for the economy, and for development of future treatments for diseases like schizophrenia and Alzheimer's.

A must read.
It takes years to see a spark transformed to a groundbreaking treatment. It all begins with basic research. Due to sustained #NIH funding, we have better therapeutics, cancer detection, vaccines. We are like 1930s Germany.

🧪 www.infotimes.us/basic-scienc...
via @markhisted.org

Trump to Add New $100,000 Fee For H-1B Visas In Latest Crackdown President Donald Trump is expected to sign a proclamation as soon as Friday that would move to extensively overhaul the H-1B visa program, requiring a $100,000 fee for applications in a bid to curb ov...

These are visas for skilled workers — doctors, scientists, and engineers.

This move will hurt US innovation and exacerbate an already serious shortage of medical professionals. In what world does this make sense?? www.bloomberg.com/news/article...

Yesterday RFK Jr said that he could name no "successes" for US health agencies. He should read this article.

• improved survival or cure for many cancers
• elimination of smallpox, polio, Hib
• reduced child mortality
• effective treatments for HIV, hepatitis C
• increased life expectancy

Again let's repeat: "it would take only 4 GOP Senators, or 6 to 7 Representatives, to save the country"

Fine, with filibuster/impeachment hurdles, say 30

Why is everyone in the media laser-focused on What Democrats Must Do? Stop giving those 10-30 Republicans free passes:

bsky.app/profile/mcop...

Former NIH chief calls research cuts “careless” and “heartless” Francis Collins, MD, PhD, lauds lifesaving research supported by the National Institutes of Health, explains why he left, and warns of scientific brain drain.

"We’re all in favor of a gold standard for science. But it’s misleading, & even a little insulting, to say that somehow NIH didn’t already support that. Everything that NIH stands for is rigor in sci...There’s some implication here that NIH has been systematically sloppy. I reject that conclusion."🛟

Opinion | America First? Not When It Comes to Your Health.

What they are doing to NIH defies all logic and reason. This admin is needlessly, irreversibly destroying one of the greatest resources our country has ever built. A few quotes from yours' truly are in the video below. Thanks to @nytopinion.nytimes.com for covering
www.nytimes.com/2025/08/24/o...

Saying goodbye to Elio Schaechter, a titan of the #Microbiology field. Farewell Elio!

AAUP, AFT Leaders Respond to Trump’s Higher Education Admissions Directive WASHINGTON—American Association of University Professors President Todd Wolfson, AFT President Randi Weingarten, and AFT Secretary-Treasurer Fedrick Ingram and issued the following statements in respo...

“This and other executive orders eliminating federal funding and forcing faculty to end legally permissible work will deprive students of opportunities for educational advancement and economic flourishing.”

—Todd Wolfson, AAUP President

Read full press release and response to Trump’s directive👇

On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...

Requiring grant review by political appointees will continue to delay and disrupt critical research and interferes with scientists’ ability to help protect the nation’s health and security. Read our statement: asm.org/press-releas...

Federal Grantmaking Gets a Christofascist Glow-Up Read my zero star review of the new Executive Order

For a very "direct" response to the new Executive Order, see

open.substack.com/pub/rasmusse...

1/3

UF, Trinity College team cracks micronutrient mystery that could be key to brain health, cancer defense Unlocking how our bodies absorb a micronutrient that we rely on for everything from healthy brain function to cancer defense.

The discovery of the missing Queuosine transporter is finally out. 15 years in the making with a combination of data mining and experimental validation performed by an international consortium funded by NIH and Irish agencies.
news.ufl.edu/2025/06/micr...

Nobody Expected the MAGA Inquisition But it’s here, and will destroy American science

For more details on the Trump/Republican ideological War on Cancer Research, @pkrugman.bsky.social has a great summary today.

paulkrugman.substack.com/p/nobody-exp...

Rachel Thomas, PhD - Deep learning gets the glory, deep fact checking gets ignored an AI researcher going back to school for immunology

"a fascinating case study on the limits of AI in biology and the harms of current publishing incentives" rachel.fast.ai/posts/2025-0...

This is a great piece, summarizing amazing deep fact checking by Valerie… | Chris Mungall This is a great piece, summarizing amazing deep fact checking by Valerie De Crecy, a must read for anyone in AI or genomics. Especially pertinent against the backdrop of the administration terminating...

www.linkedin.com/posts/chrism...