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Posts by Mariska Leeflang

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New target trial emulation study in @cmijournal.bsky.social comparing monotherapy (mostly amp) to combo (mostly amp with CRO or gent) for Enterococcus faecalis BSI (not endocarditis).

Composite outcome similar between mono & combo

#IDSky

www.clinicalmicrobiologyandinfection.org/article/S119...

1 month ago 9 4 1 0
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May 2026 Issue is now online: www.clinicalmicrobiologyandinfection.org/issue/S1198-...

1 week ago 3 2 0 0

Every disadvantage has its advantage

4 days ago 0 0 0 0
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Join the Young Investigator Workshop at #ESCMIDGlobal 2026 for practical insights and science you can actually use!

Early-career investigators are driven to deliver meaningful research, but navigating the “how” isn’t always straightforward.

📍 Room 2 (ICM Ground Floor)

👉 bit.ly/4uKdN0r

2 weeks ago 0 1 0 0
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Keihard gewerkt vandaag maar m’n winkel ziet er weer pico bello (vind ik en ik ben de baas) uit voor het begin van het seizoen volgende week.

3 weeks ago 112 1 6 0
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Psilocybin in Treatment-Resistant Major Depression This randomized clinical trial investigates the efficacy and safety of psilocybin, 25 mg, with adjunct psychotherapy in treatment-resistance major depression.

SPIN GRAND CHELEM 🏆
Psilocybin JAMA Psychiatry trial 🍄
a) Positive framing despite negative primary outcome,
b) Inconclusive results presented as supportive evidence,
c) Safety concerns downplayed with reassuring wording.
See the rest of the 🧵 for the verbatim...

1 month ago 31 18 3 1

I’m considering whether I could set this up as required reading for students to gain access to my module canvas sites. Such a great summary of important issues.

1 month ago 33 8 1 0
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Data Visualization: Bringing Data to Life in an Introductory Statistics Course Although the use of tables, graphs, and figures to summarize information has long existed, the advent of the big data era and improved computing power has brought renewed attention to the field of ...

Do you mean this one?

doi.org/10.1080/1069...

1 month ago 0 0 0 0
Data Organization in Spreadsheets
Karl W. Broman
& Kara H. Woo
Pages 2-10 | Received 01 Jun 2017, Accepted author version posted online: 29 Sep 2017, Published online: 24 Apr 2018

    1. Introduction
    2. Be Consistent
    3. Choose Good Names for Things
    4. Write Dates as YYYY-MM-DD
    5. No Empty Cells
    6. Put Just One Thing in a Cell
    7. Make it a Rectangle
    8. Create a Data Dictionary
    9. No Calculations in the Raw Data Files
    10. Do Not Use Font Color or Highlighting as Data
    11. Make Backups
    12. Use Data Validation to Avoid Errors
    13. Save the Data in Plain Text Files

ABSTRACT

Spreadsheets are widely used software tools for data entry, storage, analysis, and visualization. Focusing on the data entry and storage aspects, this article offers practical recommendations for organizing spreadsheet data to reduce errors and ease later analyses. The basic principles are: be consistent, write dates like YYYY-MM-DD, do not leave any cells empty, put just one thing in a cell, organize the data as a single rectangle (with subjects as rows and variables as columns, and with a single header row), create a data dictionary, do not include calculations in the raw data files, do not use font color or highlighting as data, choose good names for things, make backups, use data validation to avoid data entry errors, and save the data in plain text files.

Data Organization in Spreadsheets Karl W. Broman & Kara H. Woo Pages 2-10 | Received 01 Jun 2017, Accepted author version posted online: 29 Sep 2017, Published online: 24 Apr 2018 1. Introduction 2. Be Consistent 3. Choose Good Names for Things 4. Write Dates as YYYY-MM-DD 5. No Empty Cells 6. Put Just One Thing in a Cell 7. Make it a Rectangle 8. Create a Data Dictionary 9. No Calculations in the Raw Data Files 10. Do Not Use Font Color or Highlighting as Data 11. Make Backups 12. Use Data Validation to Avoid Errors 13. Save the Data in Plain Text Files ABSTRACT Spreadsheets are widely used software tools for data entry, storage, analysis, and visualization. Focusing on the data entry and storage aspects, this article offers practical recommendations for organizing spreadsheet data to reduce errors and ease later analyses. The basic principles are: be consistent, write dates like YYYY-MM-DD, do not leave any cells empty, put just one thing in a cell, organize the data as a single rectangle (with subjects as rows and variables as columns, and with a single header row), create a data dictionary, do not include calculations in the raw data files, do not use font color or highlighting as data, choose good names for things, make backups, use data validation to avoid data entry errors, and save the data in plain text files.

Every day is a good day for sharing one of the most useful papers about research data ever written. PLEASE get your people to understand and follow this advice.

www.tandfonline.com/doi/full/10....

1 month ago 1050 402 31 47
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Gisteren in Canva zelf een poster/flyer etc gemaakt (en gelijk besteld). Ik ben er best wel trots op en hoop dat het ook gaat werken. Zo tof dat je dit soort dingen gewoon zelf kan doen (dit was geen bestaand template).

1 month ago 126 9 12 0
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REACH January-March 2026 | Science Integrity Alliance REACH is a modern, interactive, and comprehensive digital magazine designed to meet the shared needs of all stakeholders in the research community.

The January-March 2026 issue of REACH is now live! 🎉

📘Inside: CRediT, the Einstein Foundation Award, Cochrane's 30th anniversary, Jennifer Byrne on paper mills, our SIA Special Report on AI Stress Points in Scholarly Publishing (Part I), and much more!
👉🏻 www.sci-integrity.com/reach-januar...

1 month ago 11 7 0 3
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'AI Is African Intelligence': The Workers Who Train AI Are Fighting Back Kenyan workers are still the underpaid labor behind AI training, moderation, and sex chatbots. The Data Labelers Association is fighting back.

I met with AI data labelers in Kenya who are organizing their colleagues to fight the brutal working conditions and horrible pay given to the workers at the "bottom of the AI supply chain." They believe the NDAs they've signed are unenforceable so are speaking out:

www.404media.co/ai-is-africa...

1 month ago 6336 3045 35 170
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Wat is het verband tussen de plant Bitterzoet (𝘚𝘰𝘭𝘢𝘯𝘶𝘮 𝘥𝘶𝘭𝘤𝘢𝘮𝘢𝘳𝘢), de uitbouw van fietsinfrastructuur langs Kempische waterlopen, en ringrot op aardappelen? Kom het te weten in de zesde aflevering van Planeet Plant! planeetplant.buzzsprout.com/2546032/epis...

1 month ago 10 2 0 0
Academic Wheel of Privilege (AWoP)

Let us know if you use the #AcademicWheelOfPrivilege in your authorship teams or in other academic contexts!

You can also follow along for updates on the Academic Wheel of Privilege on FORRT’s:
Website: forrt.org/awop/
Slack Channel: forrt.slack.com/archives/C03...

1 month ago 2 1 0 0
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Wie online een zwangerschapstest koopt, loopt de kans dat Amerikaanse techbedrijven weet krijgen van je kinderwens. Met geitenpaadjes verzamelen de drogisten gevoelige informatie over je gezondheid, om die vervolgens door te sturen aan Google of Meta.
👉 buff.ly/i7nQpEQ

1 month ago 16 9 2 0

Or right after official holidays - 4th of January or so

1 month ago 1 0 0 0
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OpenSAFELY news: you can apply to do non-COVID research, from today! | Bennett Institute for Applied Data Science We are delighted to announce that - from today - you can submit applications to the OpenSAFELY service for non-COVID-19 studies.

OpenSAFELY is open from today! Huge thanks to all who supported this vast collaboration: whole population GP data; in a productive platform; innovative privacy protections; unprecedented support from professions, privacy campaigners; &c

Now it's over to users!

www.bennett.ox.ac.uk/blog/2026/02...

1 month ago 183 87 6 18

Hi bluesky! I was wondering whether you know of any papers that discuss how much easier it is to do a replication study with agentic AI (eg Codex/Claude Code). In the absence of code, it seems like that's a great way to test whether the models reported in a paper were the ones that were fit, etc.

2 months ago 0 2 0 0

Likewise!

2 months ago 0 0 0 0
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Yay! QUADAS-3 is out!
🔬🧪
Are you planning to do a systematic review of diagnostic test accuracy? Then check out today's Annals of Internal Medicine for QUADAS-3 and its E&E document!

Changes to QUADAS-2 domains and focus on “ideal test accuracy trial”.

#DiagnosticResearch #EvidenceBasedMedicine

2 months ago 4 0 1 1
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Exploring interdisciplinarity – raising self-awareness through a comprehensive research assessment - MetaROR

For the University of Helsinki's comprehensive research assessment, researchers designed a dedicated module to capture interdisciplinarity.

Reviewers called their approach "inspiring" and did not identify major weaknesses, but do provide recommendations.

👇 Read the assessment, reviews & full text

2 months ago 6 5 2 0

Striking paper from researchers at Anthropic using a randomised control trial to look at the effects of AI use on skills acquisition.

TL:DR ‘We found that using AI assistance led to a statistically significant decrease in mastery.’
www.anthropic.com/research/AI-...

2 months ago 552 330 22 61
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AI is not a peer, so it can’t do peer review If we still believe that science is a vocation grounded in argument, curiosity and care, we can’t delegate judgement to machines, says Akhil Bhardwaj

'to treat peer review as a throughput problem is to misunderstand what is at stake. Review is not simply a production stage in the research pipeline; it is one of the few remaining spaces where the scientific community talks to itself.' 1/3

2 months ago 365 156 6 20
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The FORRT Replication Database has received a massive overhaul (FReD 2.0): We double-coded and validated all data from scratch and extended it in the course of a one-year-partnership with the @cos.io. We just switched to a faster interface thanks to @lukaswallrich.bsky.social’s wizardry.

2 months ago 23 15 1 1
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Reproducibility and open science are great, but they don't necessarily equate to rigor. You can perfectly share a study and still draw weak conclusions. True rigor lives in the questions we ask, the designs we choose, and the inferences we make.

2 months ago 21 10 1 1
Poster for an online course on epidemiology for journalists

Poster for an online course on epidemiology for journalists

During the peak of the Covid-19 pandemic, I taught three, online courses for journalists on basics of epidemiology

Course recordings and slides are still available as a free resource on my teaching website

www.teachepi.org/courses/epid...

2 months ago 117 57 0 4
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Recommended reading for all who care about universities and their role in society.
Yesterday Iris Lechner defended her PhD thesis on the epistemic responsibilities of universities in a sparkling discussion with her opponents. PhD thesis is available at: bit.ly/45EDkNz
@wcrifoundation.bsky.social

2 months ago 3 5 0 0

Wat is hier oorzaak en wat is gevolg?

2 months ago 0 0 1 0

Ik zei het toch?

Topvrouw zorg Ann van den Bruel (KCE België) kritisch over screenings: ‘Je spoort ook kankers op die je beter niet had gevonden’ en 'We kijken nu veel te naïef naar screenings.’
archive.ph/DFVWX

2 months ago 13 4 2 0
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Lekker hoor: om 5 uur 's ochtends ontbijt op bed!

3 months ago 0 0 0 0