(1/n) How can we infer single-trial communication between 🧠 regions? Check out our ICML 2025 paper: “Accurate Identification of Communication Between Multiple Interacting Neural Populations,” by Belle Liu and @jsacks.bsky.social in my lab: arxiv.org/abs/2506.19094
Nature research paper: Arousal as a universal embedding for spatiotemporal brain dynamics
go.nature.com/4nMUgYz
I agree but don’t see how that implies brain doesnt have both localized and distributed computation (my main claim). If anything, wouldn't an alternative visuomotor pathways for gripping in DF be evidence of distributed function and inability to discriminate width evidence of local computation?
of course not all brain does all things. and region x can do y, but with lots of help from other regions lots of upstream outputs. and region x can do other things too. distributed computation and localization of function live happily together in such a complex system
so then cant brain both be highly distributed and have localization of function? lesioned brain area can be necessary for some function but many other areas are also helping provide necessary inputs. I dont see how there is a dichotomy here.
New preprint from the lab, led by grad student Brandon Pratt, on the encoding properties and sensorimotor function of proprioceptive limit detectors (ie, hair plates) in the fly leg.
www.biorxiv.org/content/10.1...
Yes! I think this is because there is something satisfying about mapping a complex system to physical intuition. Idk how to say it but it feels very tangible when most things in modeling are very abstract like a graph nn or smth
Congratulations to Adrienne Fairhall, Prof. of Neurobiology and Biophysics, Adjunct Prof. of Applied Mathematics, and Adjunct Prof. of Physics, who has just been elected to the National Academy of Sciences! 🍾 🎉
All cortex?
Super excited about our 2-day @cosynemeeting.bsky.social workshop on learning that pays tribute to the diversity of timescales, teaching signals and circuits that work together to shape adaptive behaviors, and where we hope to bridge insights from behavior, dynamics, and learning rules! #cosyne2025
The International Brain Laboratory reproducibility platform paper is now published at eLife. An amazing effort by many different labs and individuals to understand and improve the reproducibility of electrophysiological measurements in mice. 🧠
I just wrote a book about how the type of work @markhisted.org is doing is key to breaking through the bottlenecks holding back new treatments for brain and mental disorders (from Alzheimers to depression). Seeing his work in danger makes me ill, and angry.
We must @standupforscience.bsky.social.
A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.
Neuropixels and Optogenetics are delighted to announce the birth of
Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics
Today in bioRxiv
960 sites, 28 emitters, 2 colors
By Lakunina, @karolinazsocha.bsky.social, Ladd, et al
www.biorxiv.org/content/10.1...
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great work! nice job with open-sourcing code and data too, was very impressed by this
do you think we need revolutionary new neurotech for this domain specialization to flourish? or do you think the existing tech + current progress is already bringing us in the right direction?
Thank you for posting this. Saw the original discussion and couldn’t understand it but this helped
