Our paper is now out in Science! Super excited to share our discovery that #mitochondria #pearling is the elusive mechanism driving the regular distribution and inheritance of #mtDNA nucleoids 🧬 [1/6]
Congrats Albert!! Looks awesome 🥳
The Federal Council is proposing the dissolution of the Swiss Science Council.
Independent fact-based, scientific advice should be available for policy decisions.
🔬🚨New preprint alert! 🚨🔬
We developed quantitative expansion microscopy (qExM) - a method to accurately count proteins in situ by combining expansion microscopy's improved labeling with statistical estimators borrowed from ecology
www.biorxiv.org/content/10.6...
#SuperResolution #CellBiology
What in the Gestapo is going on in Grand Rapids?
Watch this activist get arrested *mid-interview* for speaking out against U.S. action in Venezuela.
🦠 The Swiss Pathogen Surveillance Platform (SPSP) will fill a crucial gap in the fight against drug-resistant bacteria: detecting antimicrobial resistance genes that can spread rapidly via mobile DNA elements.
See more👇
Co-led with @jclandoni.bsky.social and fantastic support from Keaton Holt, Elena Koslover, @tatjanakleele.bsky.social , @sulianamanley.bsky.social , Sheda Ben Nejma, and Berna Durmus, you can find the preprint here: www.biorxiv.org/content/10.6...
It's wonderful to see this project out in the wild
Using photoconversion, volumetric imaging, mitochondrial segmentation, and network simulations, we identified a distinct, proliferative mitochondrial subpopulation positioned around the nucleus. From there, single mitochondria scatter new material across the cell, maintaining network in balance
🔬🥟 What do empanadas and #mitochondria have in common?
More than you'd think. Our "empanada-shaped" cells just helped uncover hidden subpopulations of mitochondria in your everyday, unpolarized cell lines. Curious how mitochondrial trafficking shapes network health?
Preprint alert 🚨 Ever wondered what role fast #mitochondria trafficking plays in the simple cells we mostly use? In @julius-w.bsky.social et al. we use mitodynamics + simulations to identify the importance of outwards transport to distribute new material and keep network balance! Link below!
Outstanding Faculty opportunity in the broad area of 'life sciences engineering' @EPFL School of Life Sciences, open to both junior and senior researchers. We may prefer metabolism-centric applications but remain open to outstanding applications across domains:
www.epfl.ch/about/workin...
Thank you #ABPHM25 for this great introduction into all of your bioinformatics tools and applications. Great people, excellent program, and a gorgeous location 🧬
At the Wellcome Genome Campus to learn more about bioinformatics and public health and it‘s very nice to see mitochondria are still following me 😍 #ABPHM25 🦠🔬
Do you LOVE organelles??
Well I am THRILLED to announce that Nellie has been published in @naturemethods.bsky.social!
Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy
🧵1/N
Stoked to share TWO preprints on mitochondrial pearling! 🎉
We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and
@gavsturm.bsky.social
et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪
Calling all #Microscopists!
Please complete the 2024 #ImageAnalysis Community Survey to inform us about your training needs!
Particularly interested in hearing from people outside Europe/North America or anyone who does not consider themselves "computational"!
forum.image.sc/t/2024-image...
Review title
Review sections graphic
Sub compartments of mitochondria graphic
Mitochondrial.dynamics graphic
🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪
www.annualreviews.org/content/jour...
#Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA
