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Posts by Lisa Gourdon-Grünewaldt

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I am very happy to have visited the Biotechnology and Cell Signalling laboratory in Strasbourg! Many thanks to Vladimir Torbeev for inviting me to present my research about foldamers and transcription factors. It was a pleasure meeting researchers working on a very wide variety of topics. 🧬

4 weeks ago 1 0 0 0

Join this event in Berlin (Oct 23–24) for the 25th anniversary of ChemPhysChem & ChemBioChem!🧪
Students: register for just 75 EUR (DM us to get the discount code) 😀

Speakers include Nobel Laureate Stefan Hell, Theresa Carlomagno, Gilles Gasser, Lynn Kamerlin, Kathrin Lang & more!

🔗 cbc-cpc2025.org

6 months ago 1 1 1 0
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Very happy about the launch of our new group @fychembio.fr, who co-organized the Trainee symposium at #ChemBioParis2025! 🧪 It was a real pleasure to host the career discussion panel with Marc Panosetti, with wonderful guests: Yimon Aye, Bridget Wagner, Ruben Ragg, and François Autelitano.

6 months ago 18 5 1 0

Fantastic week at #ChemBioParis2025!
Incredible lineup of international speakers showing the diversity and creativity in chemical biology 🧬🧪 and many participants from all around the world! 🌍
Great science, great community :D
Huge thanks to everyone involved in the organisation!

6 months ago 10 1 0 0
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Immensely happy to have received this poster prize for the use of foldamers on disordered proteins 🧬
Warm thanks to the organizers of this fantastic @foldnetuk.bsky.social symposium and to the Huc group in Munich @akhuc.bsky.social 🌍

7 months ago 10 2 0 0
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Ivan Huc Group @akhuc.bsky.social at the Banquet last night #Foldamers #Symposium

7 months ago 3 3 0 0
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🧬 Speaking at Foldamers 2025: ​​Professor Ivan Huc, Ludwig-Maximilians University, Germany

Professor Ivan Huc will share insights on protein recognition and mimicry with aromatic foldamers.

📍 Register now: foldamers2025.com
@akhuc.bsky.social

9 months ago 0 1 0 0
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One week left to register to the exciting joint ICBS / ECBS symposium! ⚡

ChemBioParis2025.com

10 months ago 1 0 0 0
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🚨 Deadline Extension! 🚨
Good news! We've extended the #ChemBioParis2025 deadlines by 2 weeks:
🗓️ Early-bird registration
🗓️ Abstract submission
Plenty of time left to join the #ChemicalBiology event of the year in Paris!
🔗 chembioparis2025.com

#ICBS2025 #ECBS2025 #ChemBio #ChemBioEvent

10 months ago 4 3 0 0
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Today is the last day to register to the ChemBioParis conference! 🏃 Don't miss this international chemical biology event in Sorbonne ⭐
#ChemBioParis2025
👉 chembioparis2025.com

10 months ago 0 1 0 0

Today is the last day to register to the ChemBioParis conference! 🏃 Don't miss this international chemical biology event in Sorbonne ⭐

10 months ago 1 1 0 0
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Come join ChemBioParis in Sorbonne!! 🧬🧪 deadline is on Tuesday ⏱️

10 months ago 0 0 0 0
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Development of Aromatic Foldamer Building Blocks Bearing Multiple Biogenic Side Chains Aromatic oligoamides, with their intrinsic rigidity and well-defined conformations, are recognized for their potential in medical applications. Similar structures are present in several naturally occurring antibiotics and have been explored for their ability to bind to various proteins and B-DNA (canonical right-handed DNA helix). This study introduces a synthetic approach to produce quinoline amino acid monomers bearing diversified side chain combinations in positions 4, 5, and 6 of the quinoline ring, designed to enhance the side chain density on helical foldamers. By increasing the number of side chains on each monomer, we aim to mimic the dense side chain presentation of α-peptides, thus improving the potential for protein surface recognition. This synthetic strategy involves efficient functionalization through cross-coupling reactions, enabling the installation of diverse side chains at strategic positions on the quinoline ring. The process has been optimized for automated solid-phase synthesis, successfully producing a 20-unit oligoamide with good purity. This foldamer, featuring multiple cationic, anionic, polar, and hydrophobic side chains, demonstrates the potential for molecular recognition in drug discovery and therapeutic applications. The methodology described here represents a significant advancement in the construction of aromatic oligoamide foldamers, providing a robust platform for further exploration of biological systems.

You can check out this paper to know how we achieved automated synthesis of aromatic oligoamide foldamers with a very wide variety of biogenic side chains! 🤖 pubs.acs.org/doi/10.1021/...

1 year ago 6 3 0 0
Affiche du 3 avril

Affiche du 3 avril

Aujourd'hui Jeudi 3 avril, #StandUpForScience partout en France pour défendre la liberté académique, les sciences, tout ce qui leur permet d’exister.

Au côtés des étudiant/es et de tous les personnels de la recherche menacés, ici et ailleurs #InSolidarity

Villes par ordre alphabétique🧵👇

1 year ago 98 49 1 1

I invite you to take a look at this communication on DNA mimic foldamers outcompeting DNA – that gives an idea of some of our group's current directions!

1 year ago 10 2 0 0
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Membres distingués 2024 - Société Chimique de France (SCF) La Société Chimique de France (SCF) a le plaisir de vous annoncer les membres distingués de l'année 2024. Pour rappel, cette distinction est décernée aux

The DCO congratulates all the new "Membres Distingués" of the SCF and especially the members of its division:
JB Behr, N Blanchard, JP Foulon, D Guianvarc'h, E Schulz, M Sollogoub, K Cariou, G Chaubet, J Oble, M Rossato.
new.societechimiquedefrance.fr/membres-dist...

1 year ago 30 8 3 1
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Interrogating the potential of helical aromatic foldamers for protein recognition A biotinylated helical aromatic oligoamide foldamer equivalent in size to a 24mer peptide was designed without any prejudice other than to display various polar and hydrophobic side chains at its surf...

We are pleased to announce that our communication on protein recognition with helical aromatic foldamers has been published in Organic & Biomolecular Chemistry! @roysocchem.bsky.social 🧪 A cornerstone for some of our current and future projects 👀
pubs.rsc.org/en/content/a...

1 year ago 9 2 0 0
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Check out our article in @angewandtechemie.bsky.social about the design of foldamers that aggregate into abiotic quaternary structures 🧩 Congrats to Shuhe! onlinelibrary.wiley.com/doi/10.1002/...

1 year ago 12 2 0 0
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🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov

1 year ago 1204 494 45 28

📯📯 Chemical Biology starter pack 📯📯
140 PIs & groups posting primary research in chemical biology.

Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj

Let's make ChemBioSky even greater again!

#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange

1 year ago 139 115 48 8
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Action Intent Links | Bluesky Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:

docs.bsky.app/docs/advance...

#AcademicSky #HigherEd #Altmetrics

1 year ago 11351 4585 167 248