A huge thanks to our collaborators and to our funders the Independent Research Fund Denmark, the Hørslev Foundation, the @carlsbergfondet.dk, and the @novo-nordisk.bsky.social for their kind support.

These findings have implications for understanding the renal response to hypercalcemia but also for kidney stone formation, where these processes can be disrupted.

When blood calcium levels rise, the kidneys increase calcium excretion. The manuscript demonstrates that this response depends on the CASR in kidney. We also show how the CASR regulates calcium permeability at the level of the renal tubule, offering new insights into calcium transport mechanisms.

Calcium-Sensing Receptor in the Thick Ascending Limb and... : Journal of the American Society of Nephrology he TAL.Activation of the CASR did not affect the driving force generated by transcellular NaCl transport across the TAL. Background The parathyroid calcium-sensing receptor (CASR) controls the rele...

Excited to share the latest publication from our lab. Now out in JASN @asnpublications.bsky.social, a leading journal in the field journals.lww.com/jasn/abstrac...

Our study examines how the calcium-sensing receptor (CASR) in the kidney helps protect against high blood calcium (hypercalcemia).

Immunosuppressive Regimen and Post-Transplantation Clinical Course.

Also published today
The Boston first in human kidney xenotransplantation case report

@nejm.org #ISNWCN

www.nejm.org/doi/full/10....

The science behind the first pig-organ transplant trial in humans The small trial will help to establish whether kidneys from genetically modified pigs can be transplanted into people safely and effectively.

Looking much forward to see the outcome from this exciting development www.nature.com/articles/d41...

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma - Nature A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patients with high-risk clear cell renal cell carcinoma.

Nature research paper: A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

https://go.nature.com/4gtHiuX

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Safety and Efficacy of Immunization with a Late-Liver-Stage Attenuated Malaria Parasite | NEJM Currently licensed and approved malaria subunit vaccines provide modest, short-lived protection against malaria. Immunization with live-attenuated Plasmodium falciparum malaria parasites is an alte...

www.nejm.org/doi/10.1056/...