www.science.org/doi/10.1126/...

"mental imagery reactivates the same sensory codes used during visual stimuli, suggesting the existence of a generative model capable of synthesizing detailed sensory contents from an abstract, semantic representation."

New paper in Imaging Neuroscience by Jonas Kransberg, Kristine B. Walhovd, et al:

Failure to detect entorhinal grid-like signals in a passive navigation human fMRI study

doi.org/10.1162/IMAG...

MDRS MDRS is a professional society dedicated to the study of memory. Members engage in basic and clinical research into how memory works and why it fails.

The Memory Disorders Research Society (www.memorydisorders.org) is now seeking nominations for new members! Self-nominations are welcome. Application is open until April 15 @ 11:59pm PT.

Reach out if you have questions about the society or its (amazing) annual meeting! forms.gle/Qn7mchoPpaqL...

New preprint by @sarahehenderson.bsky.social. The *real* blood, sweat, and tears of her PhD - trying to develop an intervention to improve episodic memory in older adults under naturalistic conditions.

"Event tagging" is simple, but holds real promise. #PsychSciSky #memory
doi.org/10.31234/osf...

Our new paper in @sfnjournals.bsky.social shows different neural systems for integrating views into places--PPA integrates views *of* a location (e.g., views of a landmark), while RSC integrates views *from* a location (e.g., views of a panorama). Work by the bluesky-less Linfeng Tony Han.

With some trepidation, I'm putting this out into the world:
gershmanlab.com/textbook.html
It's a textbook called Computational Foundations of Cognitive Neuroscience, which I wrote for my class.

My hope is that this will be a living document, continuously improved as I get feedback.

Fresh off the press from all-star post-doc Blake Elliott: www.pnas.org/doi/10.1073/...

We show that the HPC supports coincidence detection across VTA and lPFC in service of novelty-evoked invigoration. Stay-tuned for how these circuits are altered in psychosis risk.

🚀 We're hiring !

🕵️ Seeking a postdoc to study the development & individual-level organization of brain circuits supporting (in)flexible behavior in psychiatric populations.

🧠 Precision functional mapping, fMRI, normative modelling

Details 👉 tinyurl.com/3h8tcv2e

🗓️ Apply by Dec 10! Please RT 🙌

Congratulations to the brilliant Xinyue (Joy) Zhang on passing her PhD viva with flying colours and no corrections! Many thanks to her wise examiners Ed Wilding and @chrismbird.bsky.social. It's been a pleasure to have you in our lab, @xyzhang.bsky.social!

A neural state space for episodic memories Episodic memories are highly dynamic and change in nonlinear ways over time. This dynamism is not captured by existing systems consolidation theories …

I wrote a thing on episodic memory and systems consolidation. I hope you all enjoy it and/or find it interesting.

A neural state space for episodic memories

www.sciencedirect.com/science/arti...

#neuroskyence #psychscisky #cognition 🧪

Temporal dedifferentiation of neural states with age during naturalistic viewing - Communications Biology Movie fMRI data reveals age-related lengthening of neural states in visual and prefrontal regions, reflecting reduced temporal differentiation while preserved alignment with perceived events suggests stable coarse event segmentation.

The brain represents the world around us as a series of neural states - stable patterns of activity that change as we move from one event to the next.

New paper by @selmalugtmeijer.bsky.social showing that neural states get longer as people age. #PsychSciSky

nature.com/articles/s42003-025-08792-4

📣 Helpful thread about a great paper alert!

Okay - I am biased, but I am super proud of this paper and @dkvarga.bsky.social has done a truly awesome job of running this project (3 separate fMRI studies!). Thanks also to our amazing colleagues for their support.

😺 Feel free to reach out if you have any questions!

Hippocampal mismatch signals are based on episodic memories and not schematic knowledge | PNAS Prediction errors drive learning by signaling mismatches between expectations and reality, but the neural systems supporting these computations rem...

We make predictions based on general knowledge and/or specific memories. Different brain areas are active when these distinct predictions are violated – and hippocampus selectively responds to prediction errors based on episodic memory.

Cool work by @chrismbird.bsky.social @ayab.bsky.social et al!

Thanks Mariam!! This came out while I was on holiday, but we have a thread about the study on it's way...

Interestingly, I did the same today - AND IT WAS ONE OF YOUR PAPERS!!! Rather good it was too.

Proud to share the first preprint of my PhD w/ @barense.bsky.social & Mursal Jahed:

“Putting the testing effect to the test in the wild: Retrieval enhances real-world memories and promotes their semantic integration while preserving episodic integrity”

See thread! 🧵 osf.io/preprints/ps...

Whoop! Nice one Antonia!

New preprint! How do we integrate new information into prior knowledge? We find that existing knowledge enables rapid new learning but that interleaved replay during sleep promotes integration of new and old information. Modeling suggests a sleep context suppression mechanism.
osf.io/preprints/ps...

Children in England growing up ‘sedentary, scrolling and alone’, say experts Raising the Nation Play Commission report recommends ban on ‘no ball games’ signs and raising digital age of consent to 16

It's such a shame this article is framed by the headline as being about screens, when actually its about the paucity of outdoor space for play, and lack of time within education settings to make the most of what little outdoor space there is. www.theguardian.com/society/2025...

Medial temporal cortex supports object perception by integrating over visuospatial sequences Perception unfolds across multiple timescales. For humans and other primates, many object-centric visual attributes can be inferred ‘at a glance’ (i.e…

Medial temporal cortex supports object perception by integrating over visuospatial sequences

www.sciencedirect.com/science/arti...

Looks like an interesting study from @dyamins.bsky.social and colleagues

Really nice study led by Claire Lancaster and supported by other brilliant Sussex colleagues - in particular former PhD student Jess Daly. Greebles task is sensitive to subtle perceptual deficits in APOE e4 carriers in mid-life (which get worse with age and number of e4 alleles).

We recently published a new paper investigating APOE effects in Cam-CAN @camcan-2010.bsky.social movie dataset. Examining various measures we failed to find any APOE effects in healthy individuals. You can read more about it in the paper doi.org/10.1177/2398... or the thread below

Nice to see you all 👋🏻

The BNS is delighted to present this first look at the 🧠 SPRING MEETING 🧠 2025 programme, and announce we've an 🚨 EXTENDED ABSTRACT DEADLINE (Feb 17th)! 🚨 All this great science for just a £15 registration fee. Or for free if your a BNS member. Visit www.the-BNS.org.
#neuroskyence
#psychscisky

APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice Communications Biology - Lifestyle matters for genetic Alzheimer’s disease risk: In vivo imaging of mouse blood vessels and neurons shows that APOE4 reduces neurovascular function most in an...

New paper led by @silvia-anderle.bsky.social

Lifestyle matters for genetic Alzheimer’s disease risk: APOE4 reduces neurovascular function most in an already-stressed system,  when neurons are active and mice do less exercise.

I'll tell you all about it! 🧪 #neuroscience #alzheimers

rdcu.be/d74uh

Schemas, reinforcement learning and the medial prefrontal cortex - Nature Reviews Neuroscience A computational account of how schemas are learned through experience is lacking. In this Perspective, Bein and Niv synthesize schema theory and reinforcement learning research to derive computational...

Excited to share this perspective with @yaelniv.bsky.social about how schemas might be learned and instantiated via reinforcement learning, latent cause inference, and dimensionality reduction, and what's the medial prefrontal cortex might be doing for all of these www.nature.com/articles/s41...

🏆The BNS Elizabeth Warrington Prize 2025 will be awarded for distinguished work in neuropsychology/neuroscience by a person at an early stage in their career. 🧠
Call for nominations now open!
Deadline: April 1st. ⏱️
More info: www.the-bns.org/prizes

#neuroskyence
#psychscisky

Nice one Lucy!!

Great work and top-notch thread skills from @kasiamojescik.bsky.social ! Please take a look if you're a fan of memory, aging, subjective experience, or all three! #PsychSkySci #neuroskyence