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Posts by Ricardo Mallarino

If Bad Bunny can cover the history of Puerto Rico, colonialism, transatlantic slavery, hemispheric consciousness, as well as contemporary life and politics in under 14 minutes, you can do your 15- or 20-minute conference presentation with time to spare.

2 months ago 3002 605 51 87
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Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting Parenting behavior emerges from hormonally sensitive circuits, but how distinct circuit components are affected by, and contribute to, sex and state dependent changes in infant caregiving remains uncl...

New paper alert!!...🀩 Led by @blogeman.bsky.social, we identify how cell type-specific hormonal responses in the hypothalamus tunes parenting behavior in males and females 🐭🧠🍼. Highlights in thread πŸ‘‡ 1/6

www.biorxiv.org/content/10.6...

4 months ago 73 32 1 0
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Rapid compensatory evolution within a multiprotein complex preserves telomere integrity Intragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...

How to keep in step when your (protein) partner speeds up…

Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection.

Congrats to whole team!

www.science.org/doi/10.1126/...

4 months ago 120 64 6 4

This is amazing - congrats, Mia and team!!

4 months ago 1 0 0 0
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Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals Host body temperature can define a virus’s replicative profileβ€”influenza A viruses (IAVs) adapted to 40Β° to 42Β°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...

How does fever work?

Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.

This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧡

www.science.org/doi/10.1126/...

4 months ago 200 90 6 6

As a longtime fan of cool papers in @currentbiology.bsky.social, I am really thrilled to see this out!

This study sets the stage for understanding the origins of novel (vocal) behaviors.

Big shout out to the main architects of this work @xmikezheng20.bsky.social and @cliffscience.bsky.social

5 months ago 56 23 8 1
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SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT

5 months ago 119 75 1 3
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Niche-specific dermal macrophage loss promotes skin capillary ageing - Nature Capillary-associated macrophages are selectively lost over time, contributing to impaired vascular repair and reduced tissue perfusion in older mice.

When Macrophages Disappear, Skin Blood Vessels Age!
Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology
πŸ‘‡πŸ‘‡
www.nature.com/articles/s41...

6 months ago 23 12 6 0
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Insertion of an invading retrovirus regulates a novel color trait in swordtail fish For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...

I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A

5 months ago 186 69 3 15

I’d given up on social media, but I was missing too many cool papers. Case in point: this incredible new study from @cagricevrim.bsky.social and @karalmckinley.bsky.social. Simply amazing!

5 months ago 11 5 2 0
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A fascinating new study in which the humble sugar glider makes a special appearance, helping a team led by @brainevodevo.bsky.social and @fennak.bsky.social uncover the evolutionary history of a group of inhibitory neurons. Check out this thread summarizing the main findings!

5 months ago 7 2 0 1