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Posts by Benjamin Lévesque Kinder

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TDLM-Resting-State Simulation How sensitive is TDLM really? Can we actually find replay when we know it is present?

Can we really measure replay in humans using MEG with current methods? In our most recent paper we simulated replay under realistic conditions via a novel hybrid approach with astonishing results.

we're delighted that it has now been published @elife.bsky.social!
elifesciences.org/articles/108...

1 week ago 70 33 3 5
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Excited to announce our new paper in Trends in Cognitive Science (TICS) on the importance of naturalistic body movements and mobile immersive virtual reality to the study of cognition! Check it out!

www.sciencedirect.com/science/arti...

1 month ago 26 8 0 0
Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey - Scientific Data Scientific Data - Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey

Want a dataset to test ideas on neural basis of decision making or how areas interact as we make choices? Check out our data published today @rudebecklab.bsky.social. >16,000 single neurons from 22 anatomically confirmed areas in macaques performing a decision task. www.nature.com/articles/s41...

2 weeks ago 103 34 2 1

A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe www.biorxiv.org/content/10.64898/2026.02...

2 months ago 4 3 0 1

🔔PREPRINT: Sleep ripples drive single-neuron reactivation for human memory consolidation
1/9: How does sleep support human memory consolidation? To test this, we recorded hundreds of neurons in the human medial temporal lobe (MTL) across learning, wakefulness, and sleep.
doi.org/10.64898/202...

3 weeks ago 42 26 1 1

What are the systems in neuroscience that we really have something that we can call “explanation” at all relevant levels, other than reflexive feed-forward like circuits.

Here are a few that I would argue are getting there. Obviously not complete explanations but genuinely satisfying.

4 weeks ago 70 27 1 0

I had a lot of fun – and learned a lot – talking to the one and only György Buzsáki on @stimulatingbrains.org the other day – check it out here 👇👇

1 month ago 17 5 0 0
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22 years of Brain Science: what CoSyNe tells us about the evolution of Neuroscience Tracking the intellectual DNA of Computational and Systems Neuroscience through its flagship meeting

I tracked every keyword in 22 years of Cosyne abstracts to map how computational neuroscience evolved — from Bayesian brains to neural manifolds to LLMs — and where it's heading next.

1 month ago 159 70 7 18
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First ever public presentation of single cell evidence for non-spatial grid cells by Elena Gutierrez, Seb Veselic from Steve Kennerley lab. Steve an I have been dreaming of this moment for nearly 10 years. #sfn25

5 months ago 94 6 2 0

RIP efficient coding 😜

1 month ago 16 3 1 0
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Read our letter to Prime Minister Mark Carney – Canadian Association for Neuroscience Canadian Association for Neuroscience

Read CAN President Douglas Zochodne's letter to Prime Minister Mark Carney highlighting the importance of Neuroscience research and the CIHR Project Grant shortfalls.
can-acn.org/read-our-let...

1 month ago 17 11 0 0
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Claude Code 27: Research and Publishing Are Now Two Different Things Some Claude Code fan fiction about the economics of publishing with AI agents set in the very near future

This post really put together the pieces in a way that floored me. Everything is about to change and we have to confront that reality causalinf.substack.com/p/claude-cod...

1 month ago 29 10 1 3
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Low frequency oscillations – neural correlates of stability and flexibility in cognition - Nature Communications How the brain balances the flexibility and stability needed to both encode and maintain information during cognition remains poorly understood. Using MEG data and in-silico simulations, the authors sh...

2025 in @natcomms.nature.com
“Low frequency oscillations - neural correlates of stability & flexibility”

Theta/alpha oscillations can aid cortical information transfer in-silico - a mechanism in line with MEG network state transitions in several working memory tasks

www.nature.com/articles/s41...

2 months ago 6 2 0 0
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Whether the system can be flexibly redirected to prioritize specific locations has been unclear. Using large-scale #Neuropixels recordings in freely behaving rats, we find that both sweeps – and the internal direction signals driving them – are dynamically modulated moment by moment. (4/6)

2 months ago 37 10 3 2
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Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻

Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems.

See below for + details and retweet 🙏

2 months ago 75 56 3 5

Great work by Roni Tibon (not on BlueSky) - surprising that negligible difference in fMRI correlates of semantic vs episodic retrieval?

2 months ago 25 12 0 0
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Aperiodic 1/f noise drives ripple activity in humans - Nature Communications How aperiodic 1/f noise drives ripple activity in human brain and impacts on ripple detections is not fully understood. Here authors show that ripple detections should be driven by the 1/f noise, whic...

Ripple oscillations are central for memory and sleep.

But ripple detection in humans remains challenging. Here we introduce a simulation approach in @natcomms.nature.com as common ripple detectors mainly pick up 1/f noise and not genuine oscillations

👇
www.nature.com/articles/s41...

#neuroskyence

2 months ago 100 35 2 3
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New paper in Imaging Neuroscience by Holly Schofield, Matthew J. Brookes, et al:

Towards a 384-channel magnetoencephalography system based on optically pumped magnetometers

doi.org/10.1162/IMAG...

3 months ago 7 5 0 0
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Totally agree and the point is well taken. On a bayes account, although a negative result doesn’t prove ‘unnecessary’ it does lower the posterior p that C is necessary (depends on prior, n, etc. etc.)

4 months ago 5 0 1 0

Not easy (circuit out of a brain can’t behave). But wouldn’t up/do
wn modulation of a specific circuit (e.g. w/ opto) tightly controlling a behaviour (e.g. www.science.org/doi/epdf/10....) show ‘production sufficiency’ (to borrow from the TINS paper)?

4 months ago 1 0 1 0

Wouldn't demonstrating joint necessity/sufficiency for a set of circuit satisfy "causal production" as in TINS, below? Perhaps I misunderstood, but this seems like it fits that definition of causality (production) in distributed systems. Happy to be corrected if I’m missing anything!

4 months ago 1 0 1 0

The necessity/sufficiency distinction seems important here. A lesion in C with no effect tells you C is not necessary for b, but nothing about sufficiency (although brain stim in C could clarify). Likewise, C2 might be unnecessary when lesioned alone, but the set {C, C2} could be jointly necessary.

4 months ago 1 0 2 0

In my view there will be many such circuits, but if you don’t know how to look for them it will seem like everything is everywhere. But this view is not very fashionable at the moment. It will return. And then it will be unfashionable again :)

4 months ago 11 1 1 0
University Assistant/Associate Professor in Control Theory and Systems Biology Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group

We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!

www.cam.ac.uk/jobs/univers...

4 months ago 42 40 0 1
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

Well this is exciting!

The Department of Psychological & Brain Sciences at Johns Hopkins University (@jhu.edu) invites applications for a full-time tenured or tenure-track faculty member in Cognitive Psychology, in any area and at any rank!

Application + more info: apply.interfolio.com/178146

4 months ago 93 55 1 3

Prob a small effect, but the FAQ mentions they excluded multi-disciplinary journals from the sample. Some of these journals (esp. PNAS, Nat comms, etc.) tend to publish imaging > EEG afaik, it may partially reflect a shift in where imaging gets published…

4 months ago 2 0 1 0
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Building compositional tasks with shared neural subspaces - Nature The brain can flexibly perform multiple tasks by compositionally combining task-relevant neural representations.

Nature research paper: Building compositional tasks with shared neural subspaces

go.nature.com/4ocRj3n

4 months ago 45 18 0 0

Oh man. Science Neural Circuits would be my new favorite journal.

4 months ago 10 2 2 0
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Without monkeys, neuroscience has no future Research in primate brains has been essential for the development of BCIs, ANNs. New funding and policy changes put future such advances at risk.

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao.

#neuroskyence

bit.ly/47MXYLH

5 months ago 58 31 1 5
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Whole-cortex in situ sequencing reveals input-dependent area identity - Nature BARseq interrogates the expression of 104 cell-type marker genes in 10.3 million cells over nine mouse forebrain hemispheres to reveal the role of peripheral inputs on cortical area development.

Still think brain regions don’t exist? That everything is everywhere? That cell types don’t matter and that everything is a dynamical phase portrait?

Wrong.

Interconnected brain modules exist at the level of fine grained transcriptomics. www.nature.com/articles/s41...

5 months ago 69 20 3 0