Our findings suggest the intriguing possibility that cells actively tune microtubule mechanical responses based on functional needs.
Posts by BioCytoLab
We show that kinesin motor-driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self-repair and leads to filament breakage. In contrast, intracellular factors enhance microtubule resilience under mechanical stress.
🎉 Exciting news!
Our paper has been accepted and is now published in Wiley Advanced Science! 🚀
Congratulations @bucklingmt.bsky.social
Read it here: advanced.onlinelibrary.wiley.com/doi/epdf/10....
Our new preprint is live!🎉
Cytosolic factors govern vimentin network architecture and mechanics. Cytosolic components shape vimentin IF networks & mechanics - beyond minimal reconstitutions.
On bioRxiv now!
Congrats @dyuthisreekumar.bsky.social
www.biorxiv.org/content/10.6...
🚨Great News!🚨
Our latest preprint is now live on bioRxiv!
We show that MAP65-1 and PRC1 facilitate microtubule nucleation on pre-existing lattices, particularly at sites with structural defects associated with mechanical stress.
Congrats @marianattom.bsky.social
www.biorxiv.org/content/10.1...
🎉New Paper Drop🎉 We just uploaded our latest findings on bioRxiv!
We report the identification of the limits of microtubule self-repair and how microtubule integrity is maintained under mechanical load.
Congratulations @bucklingmt.bsky.social
www.biorxiv.org/content/10.1...
Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳
We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.
Congratulations @subhambiswas.bsky.social!
www.nature.com/articles/s41...