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Posts by BioCytoLab

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Our findings suggest the intriguing possibility that cells actively tune microtubule mechanical responses based on functional needs.

1 month ago 1 0 0 0

We show that kinesin motor-driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self-repair and leads to filament breakage. In contrast, intracellular factors enhance microtubule resilience under mechanical stress.

1 month ago 0 0 1 0
Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair You have to enable JavaScript in your browser's settings in order to use the eReader.

🎉 Exciting news!

Our paper has been accepted and is now published in Wiley Advanced Science! 🚀

Congratulations @bucklingmt.bsky.social

Read it here: advanced.onlinelibrary.wiley.com/doi/epdf/10....

1 month ago 7 4 1 0
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Our new preprint is live!🎉
Cytosolic factors govern vimentin network architecture and mechanics. Cytosolic components shape vimentin IF networks & mechanics - beyond minimal reconstitutions.

On bioRxiv now!

Congrats @dyuthisreekumar.bsky.social

www.biorxiv.org/content/10.6...

2 months ago 11 6 0 0
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🚨Great News!🚨
Our latest preprint is now live on bioRxiv!
We show that MAP65-1 and PRC1 facilitate microtubule nucleation on pre-existing lattices, particularly at sites with structural defects associated with mechanical stress.

Congrats @marianattom.bsky.social

www.biorxiv.org/content/10.1...

7 months ago 7 4 0 0
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🎉New Paper Drop🎉 We just uploaded our latest findings on bioRxiv!

We report the identification of the limits of microtubule self-repair and how microtubule integrity is maintained under mechanical load.

Congratulations @bucklingmt.bsky.social

www.biorxiv.org/content/10.1...

7 months ago 19 5 0 1
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Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳

We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.

Congratulations @subhambiswas.bsky.social!

www.nature.com/articles/s41...

7 months ago 31 10 0 0