Role of STAG2 & links to PARP impairment during brain development – insights for brain tumour treatment
📷 Simona Totaro et al Università degli Studi di Milano
in and on the cover @dmmjournal.bsky.social
➡️ bpod.org.uk/archive/2026...
Thank you @bpodaily.bsky.social for the feature!
I love this image. It captures some of the major processes that shape synaptic plasticity, learning, and memory. Synaptic vesicles, microtubule intrusions into the dendritic spine, clear synaptic cleft and PSD.
Thanks @bpodaily.bsky.social 👍🙏 for the highlight !
For the ones who want more context about the study : follow this 🧵
bsky.app/profile/npan...
Importin β1's role in presynaptic vesicles of hippocampal neurons for spatial memory
📷 @philipfreund.bsky.social @npanayotis.bsky.social
et al @weizmanninstitute.bsky.social in
@science.org Signaling
➡️ bpod.org.uk/archive/2026... with
John Ankers
How GTPase Rac enhances cell engulfment & its role in chimeric antigen receptor-macrophages – a promising anti-cancer immunotherapy
📹 Lauren Penfield & Abhinava K. Mishra et al @denisemontell.bsky.social @ucsantabarbara.bsky.social
in @pnas.org
➡️ bpod.org.uk/archive/2026...
A Clear Solution: Seeing living brain cells fire signals at high magnification by matching the refractive index between tissue & lens
📹 Shigenori Inagaki et al @imailab.bsky.social, Kyushu University in @natmethods.nature.com
➡️ bpod.org.uk/archive/2026... with
@rooph.bsky.social
Patterning of epiblast cells in the early embryo results from mechano-chemical response to heterogeneous tissue boundaries
📷 Takafumi Ichikawa, @pguruciaga.bsky.social et al
Kyoto University, @embl.org in @natphys.nature.com
➡️ bpod.org.uk/archive/2026...
Notch signalling pathway underlies the wrapping of neurons by glial support cells
📷 @mariebaldenius.bsky.social et al @uni-muenster.de in
@elife.bsky.social
➡️ bpod.org.uk/archive/2026... with
@antdlewis.bsky.social
Fruit fly study reveals details – molecular gradients & adhesive forces – that control preservation of the eye pattern as axons establish in the brain
📷 @leicamicrosystems.bsky.social
Melinda Kehribar et al, Free University of Berlin in
@currentbiology.bsky.social
➡️ bpod.org.uk/archive/2026...
Structured illumination microscopy framework maximises ultrastructure while eliminating background
📷 W Liu, M Zhang, W Zhu & S Xie et al
@oxfordbiochemistry.bsky.social Zhejiang Uni, Huazhong Uni of Science & Tech in @natcomms.nature.com
➡️ bpod.org.uk/archive/2026... +
@antdlewis.bsky.social
Molecular and cellular mapping of the whole mouse
📷 Margarette H. Clevenger, Denis Cipurko, Ashwini Patil et al
@uchicagopme.bsky.social, Fudan University
in @cp-cell.bsky.social
➡️ bpod.org.uk/archive/2026...
Key role for Smarcc1 protein identified in shaping the development of the optic nerve
📷 Nitay Zuk-Bar et al Tel Aviv University in @biorxivpreprint.bsky.social
➡️ bpod.org.uk/archive/2026... with
@antdlewis.bsky.social
Out of Body-shape: Changing platelets' shape from discoid to spherical reduces clotting risk in extracorporeal life support
📹Rui Ji et al @tsinghuauniversity.bsky.social in
@pnas.org
➡️ bpod.org.uk/archive/2026...
Ratio of keratin 14 & 15 proteins influences differentiation vs division by skin progenitor cells
📷 Catherine J. Redmond et al Coulombe lab
University of Michigan Medical School in
@jcb.org
➡️ bpod.org.uk/archive/2026... with
@antdlewis.bsky.social
Hyperinnervation driven by a post-natal fibroblast population underlies loss of embryo's regenerative capacity after skin injury
📷 Hannah T. Tam et al Department of Stem Cell and Regenerative Biology @harvard.edu in
@cp-cell.bsky.social
➡️ bpod.org.uk/archive/2026...
Passing the Teste: Messenger RNA injection into the testes as a way to restore sperm function in a genetic infertility disorder
📷 Charline Vilpreux & Paul Fourquin et al @ugrenoblealpes.bsky.social
in @elife.bsky.social
➡️ bpod.org.uk/archive/2026/4/9 with
John Ankers
Oligodendrocytes myelinate complex nerve circuits by each proceeding at different rates making a flexible chain of myelin sheaths
📹 @codylcall.bsky.social et al Bergles lab @jhu.edu
@nature.com
➡️ bpod.org.uk/archive/2026...
Brain organoids used to screen drug candidates for genetic mitochondrial disease Leigh Syndrome identifies utility of sildenafil (Viagra)
📷 Annika Zink, Dao-Fu Dai, Annika Wittich et al @aleprigio.bsky.social
@hhu.de in @cp-cell.bsky.social
➡️ bpod.org.uk/archive/2026... +
@rooph.bsky.social
Live imaging mouse model of Duchenne muscular dystrophy reveals impaired migration & proliferation in muscle stem cells
📷 @sardeliza.bsky.social et al @brendan-evano.bsky.social
@tajbakhshlab.bsky.social @pasteur.fr
in @natcomms.nature.com
➡️ bpod.org.uk/archive/2026...
Synthetic tick-feeding systems – cheaper, more consistent, more ethical for study than using live animal hosts
📷 Abdul Ghafar et al @unimelb.edu.au in @elsevierconnect.bsky.social The Veterinary Journal
➡️ bpod.org.uk/archive/2026... with
@rooph.bsky.social
The complex architecture of biofilm building uncovered
📹 Henri Malmi et al @utu.fi in @natcomms.nature.com
➡️ bpod.org.uk/archive/2026/4/4
CRISPR edit to activate PPARGC1A gene boosts mitochondria improving cardiac muscle repair after heart attack
📷 Mario Escobar & Saad Malik, et al @riceuniversity.bsky.social; @bcmhouston.bsky.social re paper in @moltherapy.bsky.social
➡️ bpod.org.uk/archive/2026/4/3 with @rooph.bsky.social
Greatest distance between two tumours on CT scan analysed as a prognostic marker in lymphoma treated with CAR-T
📷 Michael Winkelmann et al Department of Radiology, University Hospital, LMU Munich in @springernature.com
Cancer Imaging
➡️ bpod.org.uk/archive/2026...
Circles of Life: Intrinsic chirality or handedness of cyanobacteria moving in a water drop – advancing understanding of bacterial collective behaviour
📹 Andrej Vilfan et al, LFPB, Max Planck Institute for Dynamics and Self-Organization in @pnas.org
➡️ bpod.org.uk/archive/2026... +
John Ankers
WaveOrder – a wave-optical framework using machine learning & computation to enhance & clarify biological microscopy images
📷 Talon Chandler et al @mattersoflight.bsky.social lab @biohub.org in @arxiv-soc-ph.bsky.social
➡️ bpod.org.uk/archive/2026... with
@antdlewis.bsky.social
New high-throughput approach for cultivating neurons in 384-well plates
📷 Mark van der Kroeg et al, Dept of Psychiatry @erasmusmc.bsky.social in @elife.bsky.social
➡️ bpod.org.uk/archive/2026...
Details of how the heart's interventricular septum forms – insights into congenital heart defects
📹 @irfankathiriya.bsky.social & @benoitbruneau.bsky.social
et al @ucsanfrancisco.bsky.social & @gladstoneinst.bsky.social in @natcardiovascres.nature.com
➡️ bpod.org.uk/archive/2026...
Bacterial biofilms are an intrinsic part of kidney stones' internal structure
📷 William C. Schmidt & Ava Mousavi et al, UCLA
in @pnas.org
➡️ bpod.org.uk/archive/2026... with
John Ankers
Mesenchymal stem cells bearing high levels of CD47 can replenish cartilage in joints of a rat model of osteoarthritis
📷 Nedaa Al-Jezani et al, McCaig Institute @ucalgary.bsky.social in @elife.bsky.social
➡️ bpod.org.uk/archive/2026...
Metal Detected: Toxoplasmosis-causing parasite needs metals to thrive – metal transporter proteins are potential treatment targets
📷 @danaaghabi.bsky.social et al @clarehardinglab.bsky.social
@glasgow.ac.uk in @elife.bsky.social
➡️ bpod.org.uk/archive/2026... with
John Ankers
