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Posts by Jure Majnik

Part of page 411, the Glossary to 'Faster Than Thought', edited by BV Bowden, 1953. Copy available online at https://archive.org/details/fasterthanthough00bvbo

As well as the Cybernetics entry quoted in the post, it also has, 'Computor. "Bad spelling of computer" — Oxford English Dictionary.'

Part of page 411, the Glossary to 'Faster Than Thought', edited by BV Bowden, 1953. Copy available online at https://archive.org/details/fasterthanthough00bvbo As well as the Cybernetics entry quoted in the post, it also has, 'Computor. "Bad spelling of computer" — Oxford English Dictionary.'

"Cybernetics. A word invented by Professor Wiener to describe the field of control and communication theory, whether in the machine or in the animal. None of the authors quite understands what the word means, so it has not been used in this book."

2 weeks ago 32 8 2 0
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Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the Drosophila optic lobe - Nature Neuroscience The authors characterized the spatial origin of Drosophila medulla neurons, completing their previous characterization of the temporal and Notch origins of these neurons and allowing them to correlate...

Félix Simon's paper is out in its final form 😍
When we got into (extreme) detail in the temporal and spatial patterning of neuroblasts, Félix asked a simple question "sure, but how does this translate into neuronal cell fate?". www.nature.com/articles/s41...

4 days ago 42 23 3 3
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‘Digital sphinx’ raises questions about connectome models The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.

A new preprint shows that deep learning can make a fly walk realistically using a worm’s brain — exposing a fundamental problem with how connectome models are being built and sold to investors.

By @natmesanash.bsky.social

#neuroskyence

www.thetransmitter.org/systems-neur...

2 weeks ago 28 12 1 0
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Gene regulatory networks: from correlative models to causal explanations Nature Reviews Genetics, Published online: 09 March 2026; doi:10.1038/s41576-026-00939-1In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without compromising explanatory power.

FYI: New online! Gene regulatory networks: from correlative models to causal explanations

3 weeks ago 18 8 0 1
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First atlas of brain organization shows development over a lifetime Scans of more than 3,500 people allow scientists to draw up a guide to the brain areas that work together from birth to 100 years old.

First atlas of brain organization shows development over a lifetime - from birth to 100 years!

The tour-de-force paper is here www.nature.com/articles/s41...

🧪 @nature.com

www.nature.com/articles/d41...

3 weeks ago 26 8 2 1
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🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social

We gave a worm brain control of a fly body and it walked

What did we learn? Nothing, other than deep reinforcement learning is effective

We call it the digital sphinx

www.biorxiv.org/content/10.6...

4 weeks ago 397 147 9 27
Image of a young Christiane Nüsslein-Volhard looking at stocks of fruit flies. Image credit to MPG/W. Filser. Credit text to Headwaters of the zebrafish — emergence of a new model vertebrate by Grunwald and Eisen (2002)

Image of a young Christiane Nüsslein-Volhard looking at stocks of fruit flies. Image credit to MPG/W. Filser. Credit text to Headwaters of the zebrafish — emergence of a new model vertebrate by Grunwald and Eisen (2002)

Foundational work in #zebrafish can be credited to "fruitful" discussions between #Drosophila researchers such as José Campos-Ortega & Christiane Nüsslein-Volhard. By the late 1980s, multidisciplinary approaches honed in flies were finally applied to a vertebrate. #ZebrafishFunFacts 🧪

1 month ago 23 8 2 0
Cosyne 2026 - Cosyne Tutorial: Comparative Analysis of Neural Population Codes
Cosyne 2026 - Cosyne Tutorial: Comparative Analysis of Neural Population Codes YouTube video by Cosyne Talks

Cosyne invited me to give a long tutorial (4 hours!) on methods to quantify differences high-d neural recordings across animals, brain regions, deep neural nets, etc.

The recording is up on youtube. I hope it inspires more research on this fundamental topic!

www.youtube.com/watch?v=n44x...

1 month ago 160 56 3 1
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Youthful antics predict lifespan? Using machine learning & continuous recordings of #killifish behavior from adolescence until death, @brunetlab.bsky.social & @deisseroth.bsky.social find early-life behavior predicted future lifespan! Now published @science.org: www.science.org/doi/10.1126/... 🧪 1/2

1 month ago 56 21 3 2
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Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...

Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...

1 month ago 181 77 6 8

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

1 month ago 153 61 7 15
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22 years of Brain Science: what CoSyNe tells us about the evolution of Neuroscience Tracking the intellectual DNA of Computational and Systems Neuroscience through its flagship meeting

I tracked every keyword in 22 years of Cosyne abstracts to map how computational neuroscience evolved — from Bayesian brains to neural manifolds to LLMs — and where it's heading next.

1 month ago 159 70 7 18
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New paper hot off the (pre-)press! We dig into the evolutionary origins of neural computations for behavioral control across mice, monkeys, and humans: www.biorxiv.org/content/10.6....

As our lab's first foray into comparative analysis of neural dynamics, I’m super excited about this work! 1/18

1 month ago 137 48 7 1
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First whole-brain recording of social sound processing in a vertebrate. Surprises start in the hindbrain; thalamus gates conspecific calls; male and female brains diverge downstream. Work by @joerghenninger.bsky.social, @mh123.bsky.social sky.social and team. www.biorxiv.org/content/10.6...

1 month ago 125 49 7 3
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20 lessons in team science: Learning from the experience of the International Brain Laboratory Leveraging large-scale neuroscience datasets requires new collaborative approaches. The International Brain Laboratory (IBL) is a distributed, open-science experiment facing these challenges. To succe...

www.cell.com/neuron/abstr...

1 month ago 2 1 0 0
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An exciting study with Roberto Garza and Armin Bahl
biorxiv.org/content/10.6...
We combine high-throughput behavioral assays in larval zebrafish with drift-diffusion modeling studying integration dynamics across development and a variety of mutants . Give it a read :D

1 month ago 20 5 0 2
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🛠️ February’s most-read Tools and Resources paper introduces idtracker.ai to rethink multi-animal tracking: buff.ly/Ho0b3xz

Learn more about publishing your tools or resources with us: buff.ly/pivLQX0

1 month ago 7 3 0 1

The ratstronaut dataset is available on DANDI!

(and analyzed with @pynapple.bsky.social 😍)

1 month ago 18 3 0 0
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🔬🧠 Releasing the 1.0 version of #Suite2p and THE PAPER w/ @marius10p.bsky.social! Now with GPU acceleration. Want to use Suite2p but don’t have 100,000 neuron recordings? We show you how to get those with a standard 2p microscope #neuroscience #imaging #neuroAI www.biorxiv.org/content/10.6...

2 months ago 100 35 2 2
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New paper alert! 🚨

We found that the brain's compass is remarkably stable at two scales

1️⃣ the system maintains its internal organization for weeks
2️⃣ It "remembers" its orientation for weeks, even after a single visit

This may be key to how the brain aligns its other maps.

Paper: rdcu.be/e3waP

2 months ago 199 69 5 7
Two posts that both illustrate the variation essential to living things--one of fruit fly ovaries and the other cultured COS cells

Two posts that both illustrate the variation essential to living things--one of fruit fly ovaries and the other cultured COS cells

A perfect chance juxtaposition of posts emphasizing that variation is at the center of life, and we need approaches that highlight rather than average out that variation

2 months ago 35 8 3 0
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This is who runs this account

2 months ago 240 37 4 5
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A computational approach to visual ecology with deep reinforcement learning Animal vision is thought to optimize various objectives from metabolic efficiency to discrimination performance, yet its ultimate objective is to facilitate the survival of the animal within its ecolo...

I helped with this project during an MSc internship: arxiv.org/abs/2402.05266, I guess that might be an idea along those lines? Of course it depends a bit what one considers as being 'rich' in terms of stim/behaviour :)

3 months ago 6 0 1 0
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The commitments in the SAFE Labs Handbook.

The commitments in the SAFE Labs Handbook.

A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers.
buff.ly/K7CGFLV

3 months ago 30 10 0 0

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

3 months ago 154 63 23 2
Examples of sequences of activity seen in multiple regions of the brain

Examples of sequences of activity seen in multiple regions of the brain

Sequences are everywhere! In every brain region. And are written in stone.

Invariant Activity Sequences Across the Mouse Brain.

Out today, by Célian Bimbard, with @kenneth-harris.bsky.social.

Based on data by Célian and by @intlbrainlab.bsky.social.

www.biorxiv.org/content/10.6...

3 months ago 80 23 3 1
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“A process which led from the amoeba to man appeared to the philosophers to be obviously a progress - though whether the amoeba would agree with this opinion is not known"
- Bertrand Russell, 1976.

Time-lapse video of Vampyrella lateritia eating Spirogyra algae from Science Source/Oliver Skibbe. 🦠

4 months ago 510 155 19 33
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And here is the PDF of the 4th course @college-de-france.fr. You will find the justification and presentation of geometric representation of cell decisions, a parsimonious mathematical model for signalling and cell state transitions

tinyurl.com/yc7u296j

4 months ago 31 9 1 0

Thanks to all the co-authors, I had great fun working on this for the last couple of years :)

4 months ago 2 0 0 0

And for a TLDR/summary of the paper you can check the 'blusky'-print from the bioarxiv version of the paper: bsky.app/profile/jure...

4 months ago 2 0 1 0