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Posts by 🦠Winnie Lee🦠

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Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham on FindAPhD.com PhD Project - Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham, listed on FindAPhD.com

PhD available with @overtonlab.bsky.social Sara Jabbari and me associated with our BBSRC sLoLa project!
www.findaphd.com/phds/project... (UK students only)

1 month ago 8 10 1 0

Happy to share that I will be giving an oral flash presentation at #ESCMIDGlobal2026 to chat about all things sepsis and empiric prescribing strategies! Thank you @escmid.bsky.social for the opportunity and looking forward to seeing everyone in Munich!

3 weeks ago 3 0 0 0
What is a Superbug? The global threat of antibiotic resistance
What is a Superbug? The global threat of antibiotic resistance YouTube video by Yorkshire Philosophical Society

Check out the first of our public lectures on AMR run by the YPS - kicked off by the fantastic Prof. Jess Blair from Birmingham. What is a superbug? @jessicamablair.bsky.social @ypsyork.bsky.social @ybri-uoy.bsky.social - two more in the series coming soon!

www.youtube.com/watch?v=sFYs...

1 month ago 11 5 0 0
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President - Oxford job with Reuben College, University of Oxford | 12855105 Reuben College, Oxford, invites applications for the position of President, to succeed Professor Lord Lionel Tarassenko, who will step down as the ...

Rare opportunity to apply to become a President of Oxford’s newest college!

www.nature.com/naturecareer...

1 month ago 1 1 0 0

New #AMR pre-print
Combining antibiotics with genotoxins can efficiently suppress bacterial in high throughput experimental models.
www.biorxiv.org/content/10.6...
Fun collaboration with Nassos Typas lab led by @mulkern.bsky.social

1 month ago 19 8 2 0
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Funding Funding is often secured through Wellcome Trust or MRC DTP Fellowships. Further information about this and specific projects studying under the supervision of Departmental supervisors who have obtaine...

PhD opportunity in my lab. Working on RSV, genomics, viral escape and evolution

www.imperial.ac.uk/infectious-d...

1 month ago 2 4 0 0
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Exploring the opportunity for therapeutic drug monitoring (TDM) and precision dose antimicrobials in an outpatient antimicrobial therapy (OPAT) service: a prospective observational study AbstractObjectives. Notwithstanding the wide uptake of outpatient antimicrobial therapy (OPAT) in the UK, there is a paucity of data on antimicrobial expos

🩺🦠How well do #OPAT antimicrobials really hit PK-PD targets? Our UK prospective study shows good attainment across agents, while demonstrating the feasibility of #TDM to support #precisiondosing in outpatient infection care doi.org/10.1093/jac/... @tmrawson.bsky.social @mgilchrist123.bsky.social

2 months ago 3 2 0 0
Speakers at the Royal Society of Medicine event

Speakers at the Royal Society of Medicine event

80 years after the Nobel Prize for penicillin, antimicrobial resistance is one of societies toughest challenges. GSK, the Fleming Initiative, and the @ineosoxford.bsky.social hosted leaders at the Royal Society of Medicine to advance the global response.

5 months ago 4 4 0 0
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Now published! www.nature.com/articles/s41...

Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.

6 months ago 44 24 1 0
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Incredible week with @camo-net.bsky.social UK and India! Diving into all things AMR surveillance, data systems and stewardship strageties! Grateful to our hosts at Amrita for having us! 🇬🇧🇮🇳 #globalhealth #AMR

10 months ago 3 1 0 0
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Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China - Nature Communications The genomic epidemiology of Acinetobacter baumannii, which is rising in virulence and multidrug resistance, was explored. This study examined bloodstream infection isolates from Chinese patients in 20...

Interesting paper

Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China

'A. baumannii is evolving from a low-virulence, multidrug-resistant pathogen to a more virulent one'

www.nature.com/articles/s41...

1 year ago 20 8 0 0
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Microbial Easter 🐰 — Superbugs - The microbial world in, on and around us Fun agar plates from across the internet The diversity in microbes is breath-taking. Individual cells may not look like much under the microscope - they are just too tiny. But when they form visible ...

And this is what microbiologists do for #Easter.

#AgarArt #ScienceIsFun

🦠🧫🔬👨🏻‍🎨🎨🖌️🐣🐇🥚

1 year ago 19 10 0 2
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A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome - Nature A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistanc...

Discovery of a new class of natural antibiotics with a new mode of action to address antimicrobial resistance, a major unmet need
@mcmasteruniversity.bsky.social
@nature.com
www.nature.com/articles/s41...

1 year ago 543 143 21 12
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Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University on FindAPhD.com PhD Project - Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University, listed on FindAPhD.com

One week left to apply for this BBSRC funded PhD position in the Duncan lab, cosupervised by @thecopperdoctor.bsky.social and @ruamicro.bsky.social www.findaphd.com/phds/project...

1 year ago 15 19 2 0

Please RT. Post-doc opportunity alert! 💥 Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...

1 year ago 26 38 1 1
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Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone Healthcare environments have been identified as a significant source of multidrug-resistant bacterial infections, particularly, in vulnerable patients…

I am delighted to update that our work presented at the ICID 2024 has been published today: Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone www.sciencedirect.com/science/arti...

1 year ago 4 4 0 1
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The role of bacterial metabolism in antimicrobial resistance Nature Reviews Microbiology, Published online: 20 February 2025; doi:10.1038/s41579-025-01155-0In this Review, Ahmad et al. examine how antibiotics influence bacterial metabolism and how metabolism, in turn, affects drug efficacy and the emergence and…

New online! The role of bacterial metabolism in antimicrobial resistance

1 year ago 25 13 0 0
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Call for applications 2025 - Creation of new research groups at the Institut Pasteur - Research The Institut Pasteur launches an international call to recruit new junior research group leaders in the application of cutting-edge transdisciplinary approaches to the exploration of host-microbe, tis...

research.pasteur.fr/en/call/call...

1 year ago 36 36 0 0
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McMaster researchers develop and share free antibiotic discovery tool to fight superbugs Creators of the ESKAPE Model are putting it in scientists' hands now so they can use the tool to do in a moment what otherwise might take weeks, with the goal of accelerating the discovery of new drug...

McMaster researchers developed the free ESKAPE Model, an AI tool for identifying new antibiotics against resistant pathogens, allowing researchers to screen up to 20,000 chemicals daily.

How to access is not yet shared, but stay tuned 😊

brighterworld.mcmaster.ca/articles/esk...

1 year ago 17 4 1 1

Congrats! 🥳

1 year ago 1 0 0 0
BIGSdb query interface with section marked 'Analysis results' enabled. The dropdown list includes fields that have been registered from the hicap output JSON result: genes_identified, IS1016_hists, and predicted_serotype, which can be searched.

BIGSdb query interface with section marked 'Analysis results' enabled. The dropdown list includes fields that have been registered from the hicap output JSON result: genes_identified, IS1016_hists, and predicted_serotype, which can be searched.

BIGSdb v1.50.0 has been released, introducing support for registering fields from the output of third-party analysis tools and then using these in queries and analyses (image shows querying hicap results in H. influenzae database).

1 year ago 5 3 1 1
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Loading and unloading plasmid cargoes Plasmids are vehicles for horizontal gene transfer between cells, but they also exchange genes with associated chromosomes in a process termed 'intracellular mobility'. I discuss a recent article by K...

🆕Read my short perspective on @daganlab.bsky.social's intriguing @currentbiology.bsky.social paper that examined plasmid-mediated gene mobilisation by comparing plasmid cargoes with chromosomal sequences across almost 2000 isolates, now in Trends in Microbiology 💻💫🧬 #MicroSky

1 year ago 107 39 2 1
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At ISID 2024 to present work with Nina Zhu & Tim Rawson on using AI to predict acute kidney injury from vancomycin & VPT therapy! Visit poster #1 at 12 PM today! @CAMO_Net1 @HPRUamr #AMR #AIinMedicine Also chat to me about Microbiology Society's Knocking out AMR project 😊

1 year ago 7 0 0 0
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Research Fellow - Department of Microbes, Infections and Microbiomes - 104864 - Grade 7 This exciting BBSRC-funded project aims to mechanistically characterise the fitness costs associated with vancomycin resistance in the Gram-positive opportunistic pathogens Enterococcus faecalis and E...

JOB CLAXON!

I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.

Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

Please DM or email me if you want to discuss this post.

1 year ago 46 87 0 4
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Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions Nature Reviews Microbiology - In this Review, Scott et al. review our current knowledge of Shigella sonnei, highlighting recent insights into this globally disseminated antimicrobial-resistant...

Hot off the press - some light reading on Shigella sonnei! 🧪🧫🧬

With @ksbakes.bsky.social @yekwah.bsky.social @sydneylmiles.bsky.social @sergemostowylab.bsky.social @lshtmamrcentre.bsky.social and a bunch of others not yet on bluesky
rdcu.be/d1EAF

1 year ago 73 23 1 0
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Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.

14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell

www.sciencedirect.com/science/arti...

1 year ago 387 148 17 8

HERE's our paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection

dx.plos.org/10.1371/journal.ppat.1012679

Great job to our @Emmabeansworth.bsky.social, @gemma-langridge.bsky.social, @winnielee.bsky.social & UKHSA's Marie Chattaway & Amina Ismail Ahmed

1 year ago 5 2 1 0

Hello Blueskis. Here is a starter pack of General Microbiology. It's a small list currently. Please feel free to self-nominate and I will add you.

go.bsky.app/QgSQHJ9

1 year ago 110 66 127 5
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Health inequalities which impact the treatment of urinary tract infections Find out about this studentship opportunity on Health inequalities which impact the treatment of urinary tract infections.

PhD studentship available.

The project is VERY interdisciplinary, combing social science, biophysics and microbiology to understand inequalities of UTIs treatment and replicate them in vitro to help choose the correct antibiotic.

Pls share, home students only #AMR #MicroSky

tinyurl.com/45d8h54u

1 year ago 32 23 3 3

It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection in @PLOSPathogens

https://t.co/iDY38oiVbJ

Great job to our @EmmaBeansworth, @gemma_langridge,@Winni_l08 & @UKHSA's @MarieChattaway & Amina Ismail Ahmed

1 year ago 3 2 0 0