Advertisement Β· 728 Γ— 90

Posts by Malaka De Silva

And @paulturnermicro.bsky.social

4 weeks ago 1 1 0 0

By popular demand we have now added the option to watch the Shigella 2026 conference online! Check out virtual registration options here πŸ–₯️ 🧫 www.shigella2026.conferences-pasteur.org/registration...

1 month ago 2 4 0 1

Great news for those who aren't able to attend in person

1 month ago 0 1 0 0
Preview
MGE-UK-4 We are thrilled to invite you to the fourth edition of the MGE UK Workshop, hosted this year in the historic City of York. Mobile Genetic Elements (MGEs) are the ultimate architects of biology. MGEs i...

It is a pleasure to announce the 4th UK MGE workshop will be in York on 23rd-24th June 2026! Registration is free and we are actively looking for contributors. Interested? If so, please register via the website and select the talk option

www.ukmgeworkshop.org

We look forward to seeing you in York!

1 month ago 12 11 0 0
Post image

MENI is back! Join us in Dublin this August 2026 for our 3rd Meeting for Microbial Evolution in Ireland. We are delighted to have @rachelmwheatley.bsky.social @drrebeccajhall.bsky.social @jpjhall.bsky.social and @tweethinking.bsky.social join us as keynote speakers this year. miniurl.com/MENI

2 months ago 42 32 2 2
Preview
Registration - EMBO Workshop Shigella: from biology to prevention EMBO Workshop Shigella: from biology to prevention

To make sure the whole Shigella community will be gathered at this inaugural meeting, we have re-opened abstract submission for poster presentation until the end of the month. Please RT!
www.shigella2026.conferences-pasteur.org/registration...

2 months ago 1 3 0 0
Preview
The natural history of the emergence of sexually transmissible shigellosis Shigellosis is a gastrointestinal illness caused by bacteria belonging to one of four species of Shigella. Sexually transmissible (ST) shigellosis was first reported in 1974, but recently there has be...

Did you know shigellosis also transmits as a sexually transmissible illness? This has increased since the early 2000s with marked AMR. Read the back story on ST shigellosis emergence here, and come to Paris for #Shigella2026 to find out more! doi.org/10.1099/mgen...

3 months ago 4 3 0 0

Happy New Year Shigellophiles! There's only 105 days to go ... don't forget to get your abstract in!

3 months ago 2 3 0 1
Advertisement
Post image

Come and join us at @shigellameeting.bsky.social in Paris 2026. Registrations are now open! www.shigella2026.conferences-pasteur.org/home and follow the Shigella starter pack go.bsky.app/6Vbwhjc (message to be added)! 215 days to go!

7 months ago 18 9 2 1
Preview
EASY-edit: a toolbox for high-throughput single-step custom genetic editing in bacteria Abstract. Targeted gene editing can be achieved using CRISPR–Cas9-assisted recombineering. However, high-efficiency editing requires careful optimization f

Happy to share the published version of our genetic toolbox, EASY-edit, for simple, flexible and efficient targeted editing in E. coli!

Feel free to to try it, we can send strains and plasmids!

academic.oup.com/nar/article/...

7 months ago 19 9 0 2

β€œβ€¦we demonstrate that although human use may affect the prevalence and mobility of genomic resistance in clinical isolates, for most antibiotics, genomic resistance existed within the pangenomes of sampled pathogens prior to clinical introduction.”

Really neat stuff!

7 months ago 15 5 1 1
Preview
Heterogeneity drives plasmid maintenance in large microbial communities Microbiomes are complex systems comprised of many interacting species. Species can survive harsh or changing conditions by rapid adaptation, a process accelerated by the exchange of genetic material b...

Is the era of microbial metagenomics over? Check out our new preprint on using species abundance distributions to predict plasmid maintenance in bacterial communities: arxiv.org/abs/2509.01695

7 months ago 1 2 0 0
The interplay between ecological networks drives host-plasmid community dynamics

New preprint with my HFSP collaborators. Network structures for bacterial and plasmid interactions determine community structure and evolvability: doi.org/10.32942/X21...

7 months ago 5 3 0 0
Preview
Species interactions determine plasmid persistence in a 3-member bacterial community Microbial communities are shaped by complex forces, including interspecies interactions and the effects of mobile genetic elements such as plasmids. How these forces interact to affect community respo...

Plasmids can be lost from a bacterial community even under positive environmental selection: doi.org/10.1101/2025...

7 months ago 18 11 2 0

At last ! A tool specifically for phage-plasmid hunters. Check tyPPing by @karinailchenko.bsky.social and @eugenpfeifer.bsky.social

7 months ago 47 16 0 0
Preview
Senior Research Associate (RA2346) in University of East Anglia | UEA View details and apply for this Senior Research Associate (RA2346) vacancy in University of East Anglia. Faculty of Science School of Biological Sciences Senior Research Associate Ref: RA23...

Vacancy! We have a postdoc position at UEA to explore the microbiology of metal resistance in Gram-positive pathogens.
πŸ“ Norwich UK
πŸ—“οΈ Apply by 21st September 25
πŸ”— tinyurl.com/mrssbd7f
RPs appreciated!
@microbiologysociety.org @asm.org @aussocmic.bsky.social @femsmicro.org @norwichmicro.bsky.social

7 months ago 4 5 0 0
Preview
Research Technician (TC923) in University of East Anglia | UEA View details and apply for this Research Technician (TC923) vacancy in University of East Anglia. Faculty of Science School of Biological Sciences Research Technician (Part-Time, 0.6 FTE) R...

Vacancy! We have a Technician role at UEA to support research on metal resistance in Gram-positive pathogens.
πŸ“ Norwich UK
πŸ—“οΈ Apply by 21st September 25
πŸ”— tinyurl.com/mr3ev3ke
RPs appreciated!
@microbiologysociety.org @asm.org @aussocmic.bsky.social
@femsmicro.org @norwichmicro.bsky.social

7 months ago 3 7 0 0
Advertisement
Preview
Antimicrobial treatment options for extensively drug-resistant (XDR) shigellosis in men who have sex with men The sexual transmission of Shigella s onnei and Shigella flexneri has been observed since the 1970s between men who have sex with men (MSM) associated with living with HIV, sexually transmitted infect...

How should #XDR #shigellosis cases be treated? Our new education piece at #BMJ #SexuallyTransmittedInfections explores specific empirical treatment. Our recommendations are subsequent to our microbial genomic, phenotypic #AMR, and clinical/pharmacological analyses. sti.bmj.com/content/earl... πŸ§«πŸ’»πŸ›ŸπŸ§ͺ🧬🦠

7 months ago 12 6 0 1

232 days to go ...

7 months ago 4 1 0 0

New paper in collaboration with the @asantoslopez.bsky.social lab!

www.biorxiv.org/content/10.1...

8 months ago 25 15 0 1

Why not follow our @shigellameeting.bsky.social starterpack of people who are speaking at and attending the conference - please message to be added to the starter pack if you're planning on coming or we haven't found you yet! go.bsky.app/6Vbwhjc

8 months ago 6 4 0 2

I hope all my fellow #shigellaphiles have 20 - 24 April 2026 blocked out in their diaries for @shigellameeting.bsky.social next year in Paris! In the meantime, check out (and join) our starter pack to start community building now 🧫

8 months ago 4 6 0 0

Finally out!! It was a long time in the making, I hope you enjoy it!! #salmonella #iNTS #AMR

8 months ago 6 6 0 0

It was great fun writing this review with @gemccallum.bsky.social , even if our conclusions are rather scary. Lots of important pathogen evolution must be occurring outside of the infection context...

8 months ago 27 14 2 0
Advertisement

Huge amount of work in this paper, very proud of Hugh getting through all these benchmarking tests. We’re much more confident now using ONT-only data for our clinical questions

8 months ago 6 1 0 0
Preview
The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens - npj Antimicrobials and Resistance npj Antimicrobials and Resistance - The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens

Delighted to have this review out with @jpjhall.bsky.social!

We discuss the risk of transmission of antimicrobial resistance in the hospital sink drain microbiome, highlight studies providing evidence of transfer, and consider strategies to mitigate these risks πŸͺ πŸ¦ 

doi.org/10.1038/s442...

8 months ago 51 16 2 5
Post image

There are half a million cases of invasive non-Typhoidal Salmonella (iNTS) every year and while you might know S. Typhimurim and Enteritidis, you may not have heard of S. Panama πŸ’© 🩸 🧫 πŸ’Š Check out our latest in @lancetmicrobe.bsky.social doi.org/10.1016/j.la... and the 🧡 below to find out more 1/n

8 months ago 58 27 2 3
Conference flyer, all info is on link too

Conference flyer, all info is on link too

Please share! 🦠
Workshop on Phage Therapy in Liverpool on 25th November organised by Stineke van Houte, @jojofoth.bsky.social, @brockhurstlab.bsky.social, & Edze Westra.

Limited FREE tickets & more info here: sites.exeter.ac.uk/vanhoutelab/...

#MicroSky

9 months ago 15 13 2 0
graphical abstract of the article the extended mobility of plasmids

graphical abstract of the article the extended mobility of plasmids

Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...

9 months ago 184 93 4 9

@ksbakes.bsky.social is representing PDU at the GRC Microbial Population Biology conference this week introducing the AMR through time and space session - check out the work of the other attendees here:

9 months ago 6 2 0 0