Congrats @PoratShliomLab for this fantastic paper and thank you for your nice words about the comment. We are very happy you liked it!

The expanding role of mitochondria–lipid droplet contacts in liver and their disruption by MASLD Nature Metabolism - By determining the organellar topology and proteome of fat-oxidizing and fat-synthesizing hepatocytes, Kang et al. show that perilipin 5-mediated mitochondria–lipid...

Excited to share this commentary on the fantastic paper out today @natmetabolism.nature.com by Porat-Shliom and colleagues on the role of mitochondria and lipid droplets contacts in the liver. rdcu.be/e9uYa @ibmb-csic.bsky.social @csic.es

Extremely happy to see this out in @embojournal.org! Here we provide a guide on how to accurately determine mitochondrial membrane potential. Thanks to @marcliesa.bsky.social for the opportunity and to everyone involved! We hope you find it useful!

@ibmb-csic.bsky.social

Very happy with this comment out today! It was a fantastic teamwork effort, with invaluable input from the editor @embojournal.org and the reviewers. Thanks a lot to all involved! @csic.es @ibmb-csic.bsky.social

Measuring mitochondrial membrane potential
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....

Blocking extracellular glycine uptake mediated by GlyT1 mitigates protoporphyria

@marcliesa.bsky.social provides a Commentary on Ducamp et al. (buff.ly/W67oexo)

buff.ly/9TuVOy3

Very cool. I always wondered why BAT was lipogenic with FASN activity. Congrats!

Thank you @jclinical-invest.bsky.social for inviting me to write a commentary about the original study published yesterday by Ducamp and colleagues, which shows a metabolic strategy to treat protoporphyrias. Commentary: www.jci.org/articles/vie.... Article: www.jci.org/articles/vie....

Irene Hernando-Herráez, a researcher at the IBMB-CSIC, has been awarded a Starting Grant from the European Research Council (@erc.europa.eu), funded with €1.5 million. These prestigious grants support young scientists leading outstanding research projects. #ERCStG

🚨 Join us for the @faseborg.bsky.social
Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee. 📅 Abstract submission & Early Registration close on April 20, 2025! Don't miss out: events.faseb.org/event/mitoch... Please re-post!

We had an amazing time with the ABC family and already miss you all! Can’t wait to hear your exciting talks, have great discussions, and hit the slopes of the Alps again. #ABC2025

See you next time!🗻⛷️🚠🧬🧫🧪💙

Maria Zoghbi says she's in "ABC transporter heaven" at #ABC2025 🥰

A closer look at ABCB10 transporter dynamics may well keep you on cloud number nine... ☁️⭐️

Moving into mitochondria with Marc Liesa! ABCB10, heme and redox stress:
Some projects are literally a blood.bath... maybe sounds familiar to some other researchers out there? 😅🩸

Makes sense.

My mistake. Got conditioned by the previous post about the panel scheduled for the same day as this one, but being delayed by absence of posting. It seems that posting dates can vary significantly between study sections then.

This one was posted today and the meeting is tomorrow. Maybe postings are delayed?

Educació i innovació Ha començat una nova legislatura. Hi ha un nou govern a Catalunya i s'esperen els nous equips dels departaments. Al mes d'agost i sense conèixer els equips que acompanyaran els consellers no es poden....

Educació i innovació www.elpuntavui.cat/opinio/artic... @epons.bsky.social @jordivitria.bsky.social @pcb-ub.bsky.social @abadal.bsky.social @aristides-lopez.bsky.social @maricarmenb.bsky.social @kutandalkim.bsky.social @gaiaub.bsky.social @vcliments.bsky.social @marcliesa.bsky.social

The data of PLIN5 regulation and its mutants is so cool too.

Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).

Fantastic work! Congratulations!!

Congrats!!

Join your fellow #ABC friends in the lecture hall and on the slopes for ABC2025 in Innsbruck Feb 27-Mar03!

Register abc2025meeting.org and see our invited speakers´list below! See you in Innsbruck!🧬⛰️🏂🧪

Last @mitotalks.bsky.social by @marcliesa.bsky.social

See mitotalks.org for a link to join

Do ‘blue zones,’ supposed havens of longevity, rest on shaky science? Critics say extraordinary life spans reflect faulty record keeping, not healthy lifestyles

SHADES OF BLUE

Blue zones, supposed havens of longevity, have become a global brand. But skeptics think they rest on shaky science

www.science.org/content/arti...

Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

A profile picture of Douglas Prasher from Martin Chalfie's Nobel Lecture

Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇

The mitochondrial biliverdin exporter ABCB10 in hepatocytes mitigates neutrophilic inflammation in alcoholic hepatitis Acute liver failure caused by alcoholic hepatitis (AH) is only effectively treated with liver transplantation. Livers of patients with AH show a uniqu…

www.sciencedirect.com/science/arti...

On AI-assisted writing in graduate school What is the proper role of AI ‘assistance’ in graduate student writing? It depends on what you mean by ‘graduate’.

“The product of your education is not your thesis, it’s yourself“

@annarogers.bsky.social on why not to rely on LLM AI to write for you in graduate school. hackingsemantics.xyz/2024/writing/