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Posts by Laura Fumagalli

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C9orf72 hexanucleotide repeat expansions impair microglial response in ALS - Nature Neuroscience This study shows that C9orf72 mutations impair immune activation in ALS, affecting how brain cells communicate, and highlights key differences in the cellular and molecular pathways underlying sporadi...

C9orf72 mutations impair immune activation in ALS, highlighting key differences in the cellular and molecular pathways underlying sporadic and genetics forms of the disease

@mancusorenzo.bsky.social @c9laura72.bsky.social @baukje-bij.bsky.social @cmn-vib.bsky.social

www.nature.com/articles/s41...

5 months ago 10 2 0 0
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This weekend, our teams @cmn-vib.bsky.social & our amazing lab are trading lab coats for running shoes! We're hitting the pavement to raise funds for Alzheimer's research — a cause close to our hearts and minds. Every step we take brings us closer to a cure. StopAlzheimer

1 year ago 12 1 1 1
Microglia Annotation Tool: a transcriptional subtype detector Microglia Annotation Tool: a transcriptional subtype detector

Check out our microglia annotation tool: mancusolab.bioinf.be/microglia/in...

1 year ago 0 0 0 0

Huge thanks to all my amazing colleagues and @mancusorenzo.bsky.social for the inspiring teamwork! Alma Nazlie Mohebiany, @jypremer.bsky.social, @paulapolanco.bsky.social, @baukje-bij.bsky.social, @piewall.bsky.social, @nicola-fattorelli.bsky.social.
@viblifesciences.bsky.social

1 year ago 5 0 0 0

Thrilled to share our latest review in @natureneuro.bsky.social

We dive into the transcriptional diversity of microglia across development, disease, regions, and sexes—highlighting emerging tools + a new resource for cell state annotation.

@mancusorenzo.bsky.social @cmn-vib.bsky.social

1 year ago 8 3 2 0
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Laura Fumagalli (@mancusorenzo.bsky.sociallab) was recently awarded a pilot grant from Stichting Alzheimer Onderzoek. 🙌

This grant will support her research on the role of microglia in ALS and FTD.
mancusolab.sites.vib.be/en/news

1 year ago 11 2 0 0
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Hoe beïnvloeden mutaties van het C9orf72-gen de hersenen? - Stop Alzheimer Met dit onderzoek hoopt Fumagalli nieuwe therapeutische doelwitten te identificeren en bij te dragen aan verbeterde diagnostische en behandelingsmethoden voor FTD en ALS.

Congrats to Laura for obtaining a pilot grant from Stop Alzheimer! And thanks to Stop Alzheimer and all the donors for their incredible support to our research! @viblifesciences.bsky.social @uantwerpen.be stopalzheimer.be/nl/hoe-beinv...

1 year ago 14 1 0 0