Only 3 days left to apply for a Summer Internship in the Yewdell Lab. Don't miss out on the chance to gain exposure to what a job in "industry" actually looks like, and get a leg up towards advancing your career. Apply now! roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
Summer 2026 internship at Genentech! Join us in South San Francisco to help advance cancer treatments through computational biology. MS and PhD students welcome. Apply here: go.gene.com/d4g57
We’re recruiting a PhD Fellow in Computational Systems Immunology. Work on large-scale immune receptor datasets and develop computational models in close collaboration with experimental labs. Apply here: www.jobbnorge.no/en/available...
PhD position available in my group in Frankfurt. Explore adaptive immune responses in metastatic colorectal cancer using multi-omics and AIRR profiling. #TRR417 @loewe-fci.bsky.social
georg-speyer-haus.de/karriere/ste...
This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise:
357 validated antibodies out of 1,124 tested.
.
Thanks to NotebookLM, I no longer hoard unread paper pdfs. Now I hoard unread summaries
Exactly!
Pet peeve: studies that don't tell how they defined TCR or BCR clones
Check out our new publication: An unbiased comparison of immunoglobulin sequence aligners.
academic.oup.com/bib/article/...
ALSO! We are hiring for the last open position (Bioinformatics Research Scientist) in the TIRTL group! Love coding, math, robotics, and uncovering the immune system's secrets? You know you do, so join us! (stjude.wd1.myworkdayjobs.com/stjude/job/M...).
Readable and beautiful R plots by default!
A bit ugly too, but using only base R:
```
alpha_hex <- function(hex_code, alpha = 1){
rgb_code = col2rgb(hex_code)/255
do.call(rgb, as.list((rgb_code + (1-rgb_code) * (1-alpha))))
}
```
As someone actviely researching labs for postdoc, it helps a ton to see things beyond the publication list, like how exactly the lab contributed to those papers, and what you're currently working on which is yet unpublished. Bonus points for an alumni list and where they're now
Bi- as code comes from latin? 🤔
What I find surprising, is that naive B cells still join the response and eventually generate better, stronger binding antibodies. In other words, the early antibody feedback in this case is too weak for #originalantigenicsin to happen. More details on bioRxiv: www.biorxiv.org/content/10.1...
In new preprint we delve into early memory B cells which are the frontline in generating antibodies against a familiar threat. We found that after first COVID vaccination a lot of pre-existing memory rapidly makes antibody-secreting cells despite weak binding to the viral protein
