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Posts by Xi Chen

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A comprehensive human embryo reference tool using single-cell RNA-sequencing data - Nature Methods This resource integrates different human embryo datasets to create a transcriptional reference map of human embryonic development from zygote to gastrula.

A comprehensive human embryo reference tool using single-cell RNA-sequencing data. #SingleCell #scRNAseq #HumanEmbryo #ReferenceDataSet #NatureMethods #BioSky #SciSky ๐Ÿงช
www.nature.com/articles/s41...

1 year ago 5 2 0 1

Mark for myself to check in the future: the Fig. 4 H3K27me3 HFFc6 example is very worrying. Is this a failed experiment? Do the millions of peaks by LANCEOTRON, GOPEAKS and SEACR look real? Do they satisfy the eye test on a genome browser track?

1 year ago 3 0 0 0

I've been meaning to write a lengthy thread about our experiences with DNA methylation editing in mouse ESCs if that would be useful (or interesting?) for a niche audience here. tl;dr: it was frustrating but we learned a lot, and it ended with our shiny new pub (1/17) www.nature.com/articles/s41...

1 year ago 129 51 7 4
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I want to draw my own schematic view of droplet single cell for figures in papers, but I don't know how to use Inkscape or Illustrator or the like. What I did? I drafted it first by hand, and then use TikZ to draw! Because why not? It was fun! The tex code is here:
github.com/dbrg77/TikZ_...

2 years ago 1 0 0 0

Hello, world!

2 years ago 9 1 0 0