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Posts by Ben Fulcher

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Unfalsifiable by Design: A Year of Trying and Failing to Reproduce a Human Microbiome and Autism Study The myth of open data, reproducibility, responsibility, and accountability in science, and your role in it

How every layer of science's "self-correcting machinery" failed when Iva Veseli and I simply wanted to reproduce the findings of a high-profile study on gut microbiome and autism:

merenlab.org/2026/04/15/u...

5 days ago 160 79 12 21

Our work on time reversibility has been published online today in @apsphysics.bsky.social Physical Review Research. See below for summary :)

journals.aps.org/prresearch/a...

6 days ago 4 2 0 0
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🚨new lab preprint; brain fingerprinting entirely revisited:
Can we differentiate individuals from just seconds of neurophysiological recordings with machine learning, without resorting to black-box approaches?

In this work, Maxence Lapatrie says 'yes'.

www.biorxiv.org/content/10.6...

2 months ago 31 9 0 0
Schematic of theta waves and gamma packets recorded from the mouse visual cortex

Schematic of theta waves and gamma packets recorded from the mouse visual cortex

How does the visual cortex coordinate neural activity over spatial and temporal scales? We found broad θ waves organize local γ bursts and spiking, forming a flexible spatiotemporal code to multiplex feedforward/feedback signals. Now out in full @natcomms.nature.com: doi.org/10.1038/s414... 🧵

4 weeks ago 32 11 2 0
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a close up of a person 's hand holding a marker that says sharpie Alt: a close up of a person's hand holding a marker that says sharpie

New preprint!

So, say you're studying some critical transition. How do you catch its universality? Pair correlations? Boring!

We threw line segments at the system, looked at intersections with clusters, and uncovered static and dynamical universal behavior of MIPS!

arxiv.org/abs/2511.09444

5 months ago 6 3 1 0

a while ago, I made this feed for neuroscience/cognitive science summer schools. after some tuning, it generally manages to find cool events. 🙂

bsky.app/profile/did:...

3 weeks ago 13 7 0 0
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Scientific Publishing: Rethinking how research is reviewed and published Taking a radical new approach to the publication process resulted in eLife losing its impact factor, but authors, reviewers, editors and funders support the journal and its efforts to reform scientifi...

Scientific publishing: Rethinking how research is reviewed and published

Review of how the loss of impact factor affected submissions at eLife - uneven drop across countries, but generally holding up remarkably well and shows a new model is possible

elifesciences.org/articles/110...

4 weeks ago 84 34 2 4
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Synaptome architecture shapes regional dynamics in the mouse brain | doi.org/10.1371/jour...

How do diverse synapses relate to the spatial patterning of whole-brain dynamics? Justine Hansen explores @plosbiology.org ⤵️

1 month ago 36 16 1 0

😂🫡

1 month ago 1 0 0 0
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Coding with AI - Better Code, Better Science

My new chapter of Better Code, Better Science on AI-assisted coding is now complete! It's been completely revised in an attempt to futureproof it. Comments welcome. bettercodebetterscience.github.io/book/ai-codi...

2 months ago 46 14 0 0

New toolbox for visualizing subcortex in python and R is very well made.
Worth pivoting your research program to study subcortical structures just as an excuse to use it ;)

2 months ago 17 2 0 0
Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.

Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.

The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)!

Preprint: www.biorxiv.org/content/10.6...
Website: anniegbryant.github.io/subcortex_vi...

2 months ago 115 46 3 6

Thrilled to see the first preprint of the lab out 🤩 Check it out if you need to compare dynamics in your data and RNN (or any other combinations of dynamical systems)!

3 months ago 45 9 0 0
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Wanna compare dynamics across neural data, RNNs, or dynamical systems? We got a fast and furious method🏎️
The 1st preprint of my PhD 🥳 fast dynamical similarity analysis (fastDSA):
📜: arxiv.org/abs/2511.22828
💻: github.com/CMC-lab/fast...
I’ll be @cosynemeeting.bsky.social - happy to chat 😉

3 months ago 114 35 1 4
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OHBM 2025 | Oral Session | Stuart Oldham | Only a matter of time: developmental heterochronicity c…
OHBM 2025 | Oral Session | Stuart Oldham | Only a matter of time: developmental heterochronicity c… YouTube video by Organization for Human Brain Mapping

My very normal, by the book presentation from this years OHBM is now available. So if you weren't at OHBM, were there but happened to miss it, or if you did see it and just want to relive it all over again, here is your chance :)

I'm quite fond of this one.

www.youtube.com/watch?v=lP86...

4 months ago 17 6 2 0
Job Search

Come and join our team! We are looking for a Research Officer to help with recruitment and assessment on a large-scale human brain imaging study:

careers.pageuppeople.com/513/cw/en/jo...

4 months ago 11 12 0 0
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New preprint! Do you like ocean waves? We found similar waves on bacterial colonies! We found that this collective behavior, known as rippling, is nothing but surface waves on an active nematic. @princeton.edu @mpipks.bsky.social @ub.edu @icreacommunity.bsky.social

www.biorxiv.org/content/10.1...

4 months ago 140 45 2 3
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Finally got the job ad—looking for 2 PhD students to start spring next year:

www.gao-unit.com/join-us/

If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply!

I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮

4 months ago 81 51 1 5
Inferring intrinsic neural timescales using optimal control theory - Nature Communications Here, the authors develop novel dynamical methods to model brain regions’ intrinsic neural timescales (INTs) from data, and find that they couple whole-brain structural connectivity to dynamic switchi...

Exciting new work from @lindenmp.bsky.social and friends!

Inferring intrinsic neural timescales using optimal control theory
www.nature.com/articles/s41...

4 months ago 28 11 0 0
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How do brain areas control each other? 🧠🎛️

✨In our NeurIPS 2025 Spotlight paper, we introduce a data-driven framework to answer this question using deep learning, nonlinear control, and differential geometry.🧵⬇️

4 months ago 89 30 1 3
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GitHub - KieranOwens/tsdr: Time-series dimension reduction (TSDR) Time-series dimension reduction (TSDR). Contribute to KieranOwens/tsdr development by creating an account on GitHub.

And there's an open python repo with really clear and easy to read and code implementing the key methods:
github.com/KieranOwens/...

Take a look?! 👀

4 months ago 6 0 0 0
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Kieran explains how all the methods can be understood through these conceptual groupings, derives new relationships between existing methods, and provides some case-study demonstrations/comparisons of how insanely well they can work on data

4 months ago 3 0 1 0
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These powerful methods are underappreciated: A recent review of the field included *0* methods designed for time-series data, instead focusing on generic dimension reduction methods.

This paper assembles a diversity of >60 scientific methods for the first time, and unifies them across 7 categories.

4 months ago 1 0 1 0
Time-series dimension reduction: a comprehensive review and conceptual unification of algorithms High-dimensional multivariate time-series data are analyzed in fields such as neuroscience, climatology, and finance. Time-series dimension-reduction (TSDR) methods are important for extracting inform...

New preprint! (by Kieran Owens)

Of interest to anyone who analyzes time-series data!:

"Time-series dimension reduction: a comprehensive review and conceptual unification of algorithms"

www.techrxiv.org/users/999518...

#timeseries #dimensionreduction #complexsystems

4 months ago 7 3 1 0

Congrats to Dr Caroline Wormell from the School of Mathematics and Statistics on their recently announced DECRA award "From chaos to clarity: reliable data-driven analysis of dynamical systems."

4 months ago 9 2 0 0
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Copula-based analytical results of horizontal visibility graphs for correlated time series The visibility graph (VG) algorithm and its variants have been extensively studied in the time series analysis as they transform the time series into the network of nodes and links, enabling to charac...

Our new preprint is out in arXiv: Copula-based analytical results of horizontal visibility graphs for correlated time series arxiv.org/abs/2508.08934 This is from the collaboration with my undergraduate student Jeong-Min Lee.

8 months ago 5 2 1 1
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Identifying statistical indicators of temporal asymmetry using a data-driven approach The dynamics of time-reversible systems are statistically indistinguishable when observed forward or backward in time. A rich literature of statistical methods to distinguish irreversible dynamics fro...

If you're interested in the statistics of time-irreversibility, and how they could be used to capture novel, interpretable properties from real-world time series, take a look:
arxiv.org/abs/2511.15991
(Code here: github.com/DynamicsAndN...)

5 months ago 1 0 0 0
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The breath of comparison (of both methods and processes) also allowed us to demonstrate that all tested indices of irreversibility had weaknesses: i.e., we could always find an irreversibile process on which any given irreverisbility index will fail to detect irreversibility.

5 months ago 0 0 1 0
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We found key families of algorithmic constructions that were could accurately index irreversibility: (i) generalized autocorrelation functions; (ii) symbolic sequences; and (iii) forecasting-derived metrics. Some recapitulate concepts studied previously but in isolation; others are novel directions

5 months ago 0 0 1 0
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He we compared >6000 time-series metrics to index time reversibility from simulations of 35 different reversible and irreversible processes

5 months ago 1 0 1 0