Youre assuming Infantino has a shred of decency, and im not sure thats a given

Cherry Blossoms 🌸 Sakura Season in Japan 🇯🇵

Senescence applied to neutrophils is just silly. None of them are dividing ... and thats how its meant to be...

I want AI to do my email and admin so that I can do science and writing, not for AI to do my science and writing so I that I can do email and admin.

Congratulations to John R. Yates III, Ruedi Aebersold and Matthias Mann, recipients of the 2026 Canada Gairdner International Award.

Prof. Yates: www.gairdner.org/winner/john-...
Prof. Aebersold: www.gairdner.org/winner/ruedi...
Prof. Mann: www.gairdner.org/winner/matth...

#2026GairdnerAwards

Getting the ol' grad school gang back together with Carafe2 -- Bo Wen (@maccoss.bsky.social and Bill Noble) and @jspaezp.bsky.social (@willfondrie.com at @talusbio.bsky.social) teamed up for essentially some late night hackathons to build out Carafe for @brukercorporation.bsky.social timsTOF data.

Job opportunity for a #FlowCytometry technician, School of Biology, University of Edinburgh, UK. We do cool flow with fungi, bacteria, diatoms, space particles, as well as mammalian cells. Spectral, conventional and sorts. Join us! Details here: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Season 1 is from 97, pretty sure its only in terrible version. But quite happy its on anyway

Post Docs are junior doctors/resident doctors of the scientific world. Current funding cuts combined with their traditionally poor treatment is turning off a generation of PhD students. Long term effects will be devastating. This 'correction' will be effectively permanent.

FragPipe users: I've updated PSManalyst shiny app. Check it out and enjoy the easiest way to evaluate the quality of your runs. Now you can map peptides to protein coverage counting PSMs.
github.com/41ison/PSMan...

How bioRxiv changed the way biologists share ideas – in numbers Four million articles are now downloaded from bioRxiv every month, according to an analysis of the life-science preprint server’s first 13 years of existence.

"bioRxiv is exactly the type of living experiment we all should be striving for, to achieve our shared goals of optimizing how research evidence is shared and used.”
via @chrisnsimms.bsky.social www.nature.com/articles/d41...

Wtf??

10 euro a pint my guess

MMR (measles, mumps and rubella) vaccine Find out about the MMR vaccine for measles, mumps and rubella, including who should have it, when it's given and possible side effects.

Measles is one of the most highly infectious diseases, and it can make children seriously unwell.

But it is preventable.

Protect yourself and others by ensuring you’re up to date with your and your children’s MMRV vaccines.

Hey ChatGPT, write me a fictional paper: these LLMs are willing to commit academic fraud Mainstream chatbots presented varying levels of resistance to deliberate requests for fabrication, study finds.

"All major LLMs can be used to either commit academic fraud or facilitate junk science...guard rails are easily circumvented"

Is anyone surprised? www.nature.com/articles/d41...

Armed and ready: How Alejandro Brenes is uncovering the hidden lives of neutrophils in brain cancer Dr. Alejandro Brenes, a Wellcome Trust Early Career Fellow at the University of Edinburgh’s Institute for Regeneration and Repair, is uncovering hidden neutrophil populations in glioblastoma that coul...

Single-cell proteomics revealed neutrophil populations in glioblastoma that transcriptomics missed. Some may be blocking blood vessels & worsening outcomes. @ajbrenes.com on the hidden complexity of "soldier cells" & his journey from accidental researcher to Wellcome Trust fellow: bit.ly/46HuIGu

As journalists working today many of us are taught to recognise disinformation when we see it and fight back against it.

Unfortunately there are some who willingly seek it out and put it on their front pages. A disgrace to the profession.

Intermittent fasting evicts long-lived plasma cells from survival niche Nature Reviews Immunology, Published online: 27 February 2026; doi:10.1038/s41577-026-01286-2Zhu et al. report in Immunity that ketogenesis resulting from intermittent fasting causes the downregulation of CXCR4 expression on plasma cells, triggering their egress from the bone marrow and impaired humoral immunity.

ICYMI: Intermittent fasting evicts long-lived plasma cells from survival niche

Yikes, you know performance is bad when the figures of merit for the Astral Zoom MS2/Orbitrap MS3 comparison are # of IDs and a PCA.
Please wait until they release a new Tribrid before buying a Thermo TMT instrument (or buy an Eclipse). The Astral Zoom doesn't look suitable for that application.

Make no mistake this is a concerted and organised attempt to completely undermine science and expert opinion. This is Covid denialism on steroids and it’s on all of academia to see this for what it is and push back as strongly as possible

How ‘skull drains’ keep the brain safe from damage and pathogens Nature - Veins in the skull can rearrange their borders to accommodate patrolling immune cells, a strange behaviour called ruffling.

Veins in the skull can rearrange their borders to accommodate patrolling immune cells

go.nature.com/4tLrKul

Excited we renewed our long-term relationship with Sciex to ensure our software tools Skyline, MSConvert, Panorama, AutoQC, etc... work seamlessly with Sciex hardware. We have big plans for Skyline in the upcoming year.

Talisker tides, Isle of Skye #Scotland #IsleofSkye #Talisker www.damianshields.com

We're live-watching the 21st century version of authoritarian propaganda. Facebook, of course, was the pioneer.
doi.org/10.1038/s415...

20th century totalitarians had to do with newspapers, radio, TV.

We’ve all had samples where BCA/qubit quant correlates poorly with LC-MS TIC.
Looks like those assays aren’t always needed:
“protein quantification and physical normalization steps can be omitted…without incurring an unacceptable increase in measurement variability after computational normalization”

I just did the dumbest thing of my entire career to prove a much more serious point.

I tricked ChatGPT and Google, and made them tell other users I’m a competitive hot-dog-eating world champion

People are using this trick on a massive scale to make AI tell you lies. I’ll explain how I did it

I've seen several recent preprints using DIANN v1.9. DIANN is great and stable in several versions, except for v1.9. We tested at least 7 different versions in a publication 👉 pubs.acs.org/doi/10.1021/...
v1.9 will likely provide more IDs, but at the cost of precision.

Poly-ubiquitylated proteins proved trickier to purify for LC-MS than expected. Non-specific background swamped isolations: with histones and uncertainty!

This led us to develop Ubi-SCAPE—for characterising the poly-ubiquitylome to unprecedented purity and depth.
www.biorxiv.org/content/10.6...

This- 👇👇👇💯. I am always amazed how easily folks are swayed by CVs, without onboarding how the individual will interface with the ‘team’ now and going forward. How a hot ‘technique’ is never enough to tank a thriving collaborative ecosystem…