I talked shortly 👍

#ATCR25 acceptance notifications just went out! We had 76 abstracts of very high quality, but could only accept 8 for short talks (so 10%). Huge thanks to our review committee for making though decisions. Really excited where the #TCR field is going based on the abstracts I saw!

Important work towards one of the holy grails in cancer immunotherapy: understanding/predicting/designing TCR specificities

A functionally validated TCR-pMHC database for TCR specificity model development Accurate prediction of TCR specificity forms a holy grail in immunology and large language models and computational structure predictions provide a path to achieve this. Importantly, current TCR-pMHC ...

It's not the models, it's the data!

We show that a substantial proportion of a widely used TCR-pMHC database does not functionally validate, causing underestimation of performance of TCR-pMHC prediction models.

www.biorxiv.org/content/10.1...