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Posts by DLRamamurthy

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Excited to share a new review by @kocherlab.bsky.social and me:

Nature-inspired neuroscience

We discuss diverse sensory systems and behaviors across the animal kingdom and argue for their integration into neuroscience. New tools in diverse systems are making this possible ✨

tinyurl.com/y5y9du27

3 days ago 195 71 1 8

New preprint from my lab! We study how reinforcement learning & selective attention interact. To do so, we built a set of models describing different ways that value & reward prediction error can modulate top-down attention. We compare model outcomes to monkey data from a color value learning task

1 week ago 93 32 2 1
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Applications are open for the Lake Conference on Comparative and Evolutionary Neurobiology - co-hosted with Circuit Neuroscience Basel!

🗓️ Oct. 25-29, 2026
📍 Seattle, WA
🧠 All career stages welcomed.

🔗 alleninstitute.org/events/lake-conference-c...

1 week ago 13 10 0 2
Promotional image for the Dana Foundation's "Dana Professional Development Awards" under the NextGen Program. Application deadline is May 10, 2026. Includes a link: on.dana.org/professional-dev-awards-2026. The Dana Foundation logo appears in the bottom right corner.

Promotional image for the Dana Foundation's "Dana Professional Development Awards" under the NextGen Program. Application deadline is May 10, 2026. Includes a link: on.dana.org/professional-dev-awards-2026. The Dana Foundation logo appears in the bottom right corner.

Apply to the Dana Foundation's Professional Development Awards by May 10th. Trainees can request up to 5,000 USD for a conference, workshop, coursework, or other interdisciplinary activity that furthers your training in neuroscience and society.

🔗 https://on.dana.org/professional-dev-awards-2026

1 week ago 4 1 0 0
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Addressing degeneracy in rodent studies of cognition In order to relate neural dynamics to cognitive computations, it is critical to determine whether subjects are employing behavioral strategies that ac…

Excited to share our recent review, which highlights algorithmic and implementational degeneracy in studies of cognition: www.sciencedirect.com/science/arti...

2 weeks ago 39 13 0 0
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For #NSF and #NIH watchers, Grant Witness now has interactive data on numbers of grants and total funding obligations, broken down by institute and directorate, new awards and non-competitive renewals.

The stranglehold on new awards is still a disaster.

grant-witness.us/funding_curv...

3 weeks ago 282 159 5 21
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Wait… localized norepinephrine transients in the awake visual cortex?!
Who would have guessed this neuromodulatory signal is that spatially precise, right where visual processing is happening. Brain state control just got a lot more local. @ruedigersarah.bsky.social www.nature.com/articles/s41...

3 weeks ago 108 34 11 3
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I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

4 weeks ago 1710 569 50 30
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NIH grant terminations affected women scientists more than men, study finds A new paper shows that women, particularly those early in their careers, have been disproportionately affected by NIH grant terminations

A new paper suggests that grant terminations from the NIH over the past year may have further punctured the so-called "leaky pipeline" because women were more impacted by grant terminations than men

www.statnews.com/2026/03/23/n...

4 weeks ago 165 101 1 7
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This is heartbreaking and it’s coming for more of us. My daily panic is focused on figuring out how I am going to fund students and keep my lab open without another grant, and I’m not alone. So many of us want to be here, do science, and mentor but without federal support, our labs will close. 💔

1 month ago 28 18 1 0

To accommodate applicants and PIs attending Cosyne, we’ve extended the MCN application deadline to Sunday, Mar 22.

Please repost.

1 month ago 10 15 0 0
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22 years of Brain Science: what CoSyNe tells us about the evolution of Neuroscience Tracking the intellectual DNA of Computational and Systems Neuroscience through its flagship meeting

I tracked every keyword in 22 years of Cosyne abstracts to map how computational neuroscience evolved — from Bayesian brains to neural manifolds to LLMs — and where it's heading next.

1 month ago 159 70 7 18
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Join us at TENSS 2026 to open black boxes, explain how things/brains work and debate the impact (or lack or it) of various new technologies on understanding of the brain and on society. tenss.ro Apply by: March 15th!

1 month ago 18 17 0 0

Excited to introduce ScaRCaMP — a highly blue-light resistant red GECI. 🔴

Now live on bioRxiv and marking my first PhD preprint (2nd for the Marko lab).

Would love feedback from the community!!

1 month ago 4 3 0 0
Attention-related modulation in the superior colliculus encodes perceptual sensitivity, but not perceptual choice Nature Communications, Published online: 28 February 2026; doi:10.1038/s41467-026-69954-4The specific contributions of different SC (superior colliculus) neuron subtypes to the diverse perceptual and behavioral aspects of attentional performance remain unclear. Here authors show that neurons in the SC support visual spatial attention by enhancing perceptual sensitivity and motor bias, without reflecting internal perceptual decisions or choice accuracy, revealing its unique role in transforming attention into action.

Attention-related modulation in the superior colliculus encodes perceptual sensitivity, but not perceptual choice @natcomms.nature.com

1 month ago 0 1 0 0
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Neuroscience has a species problem If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

Differences between species should be treated as informative constraints that refine theory, not as inconsistencies to be explained away, writes @suthanalab.bsky.social.

#neuroskyence

www.thetransmitter.org/animal-model...

2 months ago 22 9 0 1
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2026 Neurobiology of Cognition (GRS) Seminar GRC The 2026 Gordon Research Seminar on Neurobiology of Cognition (GRS) will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.

Trainees: check out the Neurobiology of Cognition Gordon Research Seminar that is taking place this summer in New Hampshire. The theme is "Cells, Circuits, and Computation".
www.grc.org/neurobiology...

2 months ago 18 7 0 0
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Do you work or study in the fields of psychology, neuroscience, computer science, artificial intelligence, or philosophy?

What does the term 'representation' mean to you?

We invite you to participate in a brief survey on key conceptual questions across fields.

eu.surveymonkey.com/r/VX9GNXM

2 months ago 66 60 4 3
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Duration between rewards controls the rate of behavioral and dopaminergic learning - Nature Neuroscience Cue–reward learning rate scales proportionally with the time between rewards. Consequently, learning over a fixed duration is independent of the number of trials. This challenges trial-based dopamine ...

Big if true. Anyone know if human learning curves are also (mostly) trial count independent?

www.nature.com/articles/s41...

2 months ago 0 1 0 0
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🔬🧠 Releasing the 1.0 version of #Suite2p and THE PAPER w/ @marius10p.bsky.social! Now with GPU acceleration. Want to use Suite2p but don’t have 100,000 neuron recordings? We show you how to get those with a standard 2p microscope #neuroscience #imaging #neuroAI www.biorxiv.org/content/10.6...

2 months ago 100 35 2 2
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From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity.

Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity, writes @lmprida.bsky.social.

#neuroskyence

www.thetransmitter.org/defining-cel...

2 months ago 21 15 0 1

Konstanz School of Collective Behavior 2026 is one of a kind school where students delve into state of the art research on collective behavior.
Apply here: www.exc.uni-konstanz.de/kscb/applica...
Deadline: March 15th, 2026
@cbehav.bsky.social @mpi-animalbehav.bsky.social @uni-konstanz.de

2 months ago 12 10 0 3

Baseline activity of V1 interneurons connects pupil-linked arousal to engaged behavioral state www.biorxiv.org/content/10.64898/2026.02...

2 months ago 3 2 0 0
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Orofacial behaviors, not eye movements, govern neural activity in mouse visual cortex www.biorxiv.org/content/10.64898/2026.02...

2 months ago 6 2 0 0

Presynaptic control of top-down signaling in neocortical layer 1 www.biorxiv.org/content/10.64898/2026.01...

2 months ago 8 2 0 0
NOT-OD-26-020: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NOT-OD-26-020. OD

Notice of Extension to Early-Stage Investigator (ESI) Eligibility Period by NIH: Investigators whose ESI end date was in Sept, Oct, or Nov 2025 will have ESI status extended through March 31, 2026

But what about if the end date was Dec 25 or Jan 26?
grants.nih.gov/grants/guide...

2 months ago 1 4 0 0
A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function There are several plausible algorithms for cortical function that are specific enough to make testable predictions of the interactions between functionally identified cell types. Many of these algorithms are based on some variant of predictive processing. Here we set out to experimentally distinguish between two such predictive processing variants. A central point of variability between them lies in the proposed vertical communication between layer 2/3 and layer 5, which stems from the diverging assumptions about the computational role of layer 5. One assumes a hierarchically organized architecture and proposes that, within a given node of the network, layer 5 conveys unexplained bottom-up input to prediction error neurons of layer 2/3. The other proposes a non-hierarchical architecture in which internal representation neurons of layer 5 provide predictions for the local prediction error neurons of layer 2/3. We show that the functional influence of layer 2/3 cell types on layer 5 is incompatible with the hierarchical variant, while the functional influence of layer 5 cell types on prediction error neurons of layer 2/3 is incompatible with the non-hierarchical variant. Given these data, we can constrain the space of plausible algorithms of cortical function. We propose a model for cortical function based on a combination of a joint embedding predictive architecture (JEPA) and predictive processing that makes experimentally testable predictions. ### Competing Interest Statement The authors have declared no competing interest. Swiss National Science Foundation, https://ror.org/00yjd3n13 Novartis Foundation, https://ror.org/04f9t1x17 European Research Council, https://ror.org/0472cxd90, 865617

Our work with @georgkeller.bsky.social on testing predictive processing (PP) models in cortex is out on biorvix now! www.biorxiv.org/content/10.6... A short thread on our findings and thoughts on where we should move on from PP below.

2 months ago 49 16 2 1
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Cholinergic modulation of dopamine release drives effortful #behavior Nature, Published online: 28 January 2026; doi:10.1038/s41586-025-10046-6In the nucleus accumbens, acetylcholine boosts dopamine release to promote effortful behaviour.

Cholinergic modulation of dopamine release drives effortful #behavior @Nature.com

2 months ago 0 1 0 0
Frequently Asked Questions (FAQs) | Grants & Funding

"NIH will provide a warning when the Common Forms are not used but will not withdraw applications that don’t comply with the use of the Common Forms. We expect the leniency to be in place through May 2026"

grants.nih.gov/faqs#/common...

2 months ago 6 10 1 2
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience

If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd
parisneuro.ovh

2 months ago 15 14 3 0
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