front cover of issue 8 of ‪Analyst: A smart self-protected DNAzyme walker that enables the rapid, specific and simultaneous isolation and quantification of sEVs

On the front cover of issue 8 of ‪Analyst:
Self-protected circular DNAzyme for integrated enrichment and quantification of small extracellular vesicles.
Zheng Chen, Zhizeng Wang, Xiaohui Chen, Yang Luo et al.
pubs.rsc.org/en/content/a...

#NMRchat Monte Carlo-like peaks assignment using a Time-Resolved in-situ NMR approach for complex reaction monitoring: a case study of the photodegradation of Retinyl Acetate pubs.rsc.org/en/Content/ArticleLandin...

TOC Graphic

Design of a “turn-on” colorimetric sensor for AChE inhibitors based on the instability of metal–organic frameworks pubs.rsc.org/en/Content/ArticleLandin...

Characterizing microscopic calcification deposits on acrylic intraocular lenses Intraocular lenses (IOLs) are implanted into the eyes during cataract surgery to improve vision. A rare complication following IOL implantation is the formation of crystallized deposits on the lenses,...

The collaboration between researchers at the Lumigen Instrument Center (LIC) and Kresge Eye Institute was published in Analyst: doi.org/10.1039/D5AN...

A paper-based immunoassay with signal amplification for the sensitive detection of nucleocapsid protein toward the diagnosis of long COVID Long COVID is characterized by persistent symptoms, including fatigue, cognitive impairment, and respiratory issues, affecting a considerable number of individuals post-infection. The underlying mecha...

In the latest issue Analyst:
A paper-based immunoassay with signal amplification for the sensitive detection of nucleocapsid protein toward the diagnosis of long COVID.
#OpenAccess from Abraham K. Badu-Tawiah et al.
Read now: pubs.rsc.org/en/content/a...

Digital fluorescent pH probes: polymer-based design, fluorescence response, mechanism, functional tuning and application to logic operation in live cells We report fluorescent digital pH probes based on a polymeric design comprising thermoresponsive, proton-binding and environment-sensitive fluorescent units. At selected temperatures, fluorescence swit...

In the latest issue of ‪Analyst:
Digital fluorescent pH probes: polymer-based design, fluorescence response, mechanism, functional tuning and application to logic operation in live cells.
#OpenAccess from Seiichi Uchiyama et al
@utokyoofficial.bsky.social
Read now: pubs.rsc.org/en/content/a...

Proton transfer reagent cations for ion–ion charge state manipulation of high mass negatively-charged analytes in an electrodynamic ion trap This work summarizes the criteria for a useful reagent for ion/ion proton transfer in an electrodynamic ion trap with specific emphasis on proton transfer to high mass multiply-charged analyte ions. A...

In the latest issue of Analyst:
Proton Transfer Reagent Cations for Ion-Ion Charge State Manipulation of High Mass Negatively-charged Analytes in an Electrodynamic Ion Trap.
#OpenAccess from Scott A McLuckey
@purduechemistry.bsky.social @sethhhhhhhhhhhhhhh.bsky.social
pubs.rsc.org/en/content/a...

Metal-organic framework-based molecularly imprinted polymers for dispersive solid-phase extraction of fluoroquinolones in coastal zone water and biological samples pubs.rsc.org/en/Content/ArticleLandin...

#chemsky #analyst

The @analyst.rsc.org Emerging Investigator Lectureship is opening for nominations soon. Be sure to share and send us your nominations by 30th June 2026!

www.rsc.org/standards-an...

#NMRchat High- and low-field NMR in binary solvent gradients pubs.rsc.org/en/Content/ArticleLandin...

Join us at Burlington House on 16th June for our Analyst 150th Anniversary Symposium! Hear from our Analyst Editorial Board members on a range of analytical chemistry topics.

📅 Register by 1st June

www.rsc.org/events/detai...

Differences in α-synuclein conformational states in physiologically relevant pH/Na+ concentrations and ammonium acetate solutions unveiled by native mass spectrometry Native mass spectrometry implemented with theta emitters was used to demonstrate differences in conformational states of wild-type, A53T mutant, and truncated α-synuclein dissolved at physiologically ...

In the latest issue of ‪Analyst:
Differences in α-synuclein conformational states in physiologically relevant pH/Na+ concentrations and ammonium acetate solutions unveiled by native mass spectrometry.
#OpenAccess from Scott A. McLuckey et al @purduechemistry.bsky.social
pubs.rsc.org/en/content/a...

(Analyst) Mass Spectrometry Imaging in Spatial Biology of Pancreatic Cancer: Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D5AN01264C, Critical ReviewNadine Nieste, Steven W. M. Olde Damink, Ron M.A. Heeren, E. Cuypers, Stefan Bouwense
Pancreatic cancer remains one of… (RSS) #MassSpecRSS #analyst

Studying the evolutionary potential of ancestral aryl sulfatases in the alkaline phosphatase family with droplet microfluidics Characterizing the dynamics and functional shifts during protein evolution is essential, both for understanding protein evolution and for rationalizing efficient strategies for e.g. enzymes with desir...

In our latest issue:
Studying the evolutionary potential of ancestral aryl sulfatases in the alkaline phosphatase family with droplet microfluidics.
Erich Bornberg-Bauer, Tomasz S. Kaminski, Andreas Lange et al
@uni-muenster.de @cam.ac.uk @northumbriauni.bsky.social
pubs.rsc.org/en/content/a...

Front cover of issue 6 of ‪Analyst

On the front cover of issue 6 of ‪Analyst:
Deterministic droplet-based co-encapsulation of single cells through inertial and hydrodynamic focusing.
#OpenAccess from Byeong-Ui Moon.
Read now: pubs.rsc.org/en/content/a...

Front cover of issue 6 of ‪Analyst

On the front cover of issue 6 of ‪Analyst:
Deterministic droplet-based co-encapsulation of single cells through inertial and hydrodynamic focusing.
#OpenAccess from Byeong-Ui Moon.
Read now: pubs.rsc.org/en/content/a...

(Analyst) A Practical Framework for Super-resolution of Mass Spectrometry Images via Adaptation of Deep Learning Models: Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00012F, PaperYinghao Cao, Yuting Tan, Chang Li, Erping Long, Lin Wang
Achieving high spatial… (RSS) #MassSpecRSS #analyst

TOC Graphic

Nucleic acid aptamer-functionalized magnetic MIL-53(Al)-NH2 for highly selective magnetic dispersion solid-phase extraction of chloramphenicol pubs.rsc.org/en/Content/ArticleLandin...

(Analyst) Study on low temperature enrichment-headspace sampling-proton transfer reaction-mass spectrometry (LTE-HS-PTR-MS) for highly sensitive analysis of trace exhaled VOCs: Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00175K, PaperJie Jin, Wei Xu, Ning Zhang, Qi… (RSS) #MassSpecRSS #analyst

TOC Graphic

#NMRchat Development of advanced voltammetric method for telmisartan and study of oxidation mechanism on boron-doped diamond electrode pubs.rsc.org/en/Content/ArticleLandin...

RACI 2026

Sensors & Diagnostics and @analyst.rsc.org are proud to sponsor the RACI Analytical and Environmental Chemistry Division's awards for the best posters at the upcoming RACI National Congress 2026, 5-10 July, in Perth, WA, Australia! www.racicongress.org.au

front cover of issue 5 of ‪Analyst

On our front cover:
Förster resonance energy transfer-based anion-responsive nanoemulsion optodes: the importance of fluorescent dye liquid lipophilicity and ionophore–dye interaction for stable and background-free anion response
#OpenAccess from Hideaki Hisamoto et al
pubs.rsc.org/en/content/a...

Urinary Metabolomic Characterization of Meclofenoxate Based on UHPLC-Q Exactive HF Orbitrap MS Technology #Analyst pubs.rsc.org/en/content/a...

(Analyst) Urinary Metabolomic Characterization of Meclofenoxate Based on UHPLC-Q Exactive HF Orbitrap MS Technology: Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D5AN01344E, PaperBing Liu, Wennuo Xu, Tingyuan Zheng, Quan Zhong Li, Jingjing Zhao
To investigate the… (RSS) #MassSpecRSS #analyst

MOF-metal nanohybrid-assisted charge transfer amplification for electrochemical biosensing of MUC1 Cancer Biomarker pubs.rsc.org/en/Content/ArticleLandin...

Studying the evolutionary potential of ancestral aryl sulfatases in the alkaline phosphatase family with droplet microfluidics Characterizing the dynamics and functional shifts during protein evolution is essential, both for understanding protein evolution and for rationalizing efficient strategies for e.g. enzymes with desir...

New paper! 📢
The authors used droplet microfluidics to study aryl sulfatases and their ancestors. They show higher mutation rates gave a wider distribution of active variants but fewer improved variants overall and highlight the need to test diverse mutagenesis regimes.
doi.org/10.1039/D5AN00865D

Proton Transfer Reagent Cations for Ion-Ion Charge State Manipulation of High Mass Negatively-charged Analytes in an Electrodynamic Ion Trap #Analyst pubs.rsc.org/en/content/a...

A promotional banner for Analytical Methods featuring the theme “Point-of-care diagnostics” with a submission deadline of 13 July 2026. The background shows an abstract scientific image with soft, colorful light effects. Below the text, six rectangular profile images of different individuals are displayed, each with a name beneath: Stefano Cinti, Ningtao Cheng, Camellia Bala, Sevinc Kurbanoglu, Eden Morales-Narváez, and Waleed Alahmad. At the bottom left, the words “Submit now” appear, and at the bottom right is the Royal Society of Chemistry logo.

📢 Call for papers! Analytical Methods is launching a collection on Point‑of‑care diagnostics, focusing on paper devices, lab‑on‑chip, wearables, smartphone tools, advanced sensing & more!

📆Submit by 13 July 2026.

Find out more 👉 blogs.rsc.org/ay/2026/02/1...

#chemsky

front cover of issue 4 of ‪Analyst: Light changing colour when traversing a nanostructured material

On the front cover of issue 4 of ‪Analyst:
Diffusion kinetics of volatile organic compounds monitored by nanohole surface plasmonics.
#OpenAccess from Hans-Peter Loock et al @hploock.bsky.social @uvic.ca
Read now: pubs.rsc.org/en/content/a...