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Posts by Drugs for Neglected Diseases initiative (DNDi)

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📢 Reminder

Join us for a #dengue side event to explore:
🔬 Integrated surveillance and data-driven decision-making
💊 R&D for new diagnostics, vaccines, and treatments
🤝 Regional cooperation and equitable access to health technologies

Info & registration👉 community.pasteur-network.org/events/208484

2 days ago 2 2 0 0
Manufacturing medicines for NTDs, with Dr Stephen Robinson
Manufacturing medicines for NTDs, with Dr Stephen Robinson YouTube video by Drugs for Neglected Diseases initiative (DNDi)

What if we told you that the secret to developing a life-saving sleeping sickness pill was making it look... exactly like a plain white tablet? 💊🧐 Dr. Stephen Robinson of @dndi.org breaks down the fascinating science of turning complex molecules into affordable medicine https://bit.ly/4sIj8Uz

3 days ago 2 3 1 0

Thanks for sharing!

3 days ago 0 0 0 0
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Prognostic models predicting clinical outcomes in patients diagnosed with visceral leishmaniasis: a systematic review Background Visceral leishmaniasis (VL) is a neglected tropical disease prevalent in populations affected by poverty and poor nutrition. Without effective treatment, death is the norm. Prognostic model...

A new study in BMJ Public Health shows current models predicting outcomes from visceral leishmaniasis are outdated, at high risk of bias, & miss regions like South Asia. None predict relapse or PKDL, only death. The authors urge caution when using them. Read more: doi.org/10.1136/bmjph-2024-001196

3 days ago 4 1 0 0
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As a trusted steward of our financial integrity, the Board Treasurer helps ensure that DNDi remains accountable, sustainable, and equipped to deliver on our mission.

📆 Deadline: 27 April
👉 Details & how to apply: dndi.org/news/2026/dn...
📣 Help us spread the word!

3 days ago 0 0 0 0
Jaqueline's story with leishmaniasis treatment
Jaqueline's story with leishmaniasis treatment YouTube video by Drugs for Neglected Diseases initiative (DNDi)

When Jaqueline was diagnosed with cutaneous #leishmaniasis at 10, she endured painful injections & walked 13k to receive treatment at the health unit.

We aim to develop an entirely new generation of all-oral medicines that make treatment easier for every patient.

youtube.com/shorts/g5c15...

5 days ago 1 0 0 0
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MedChemica, Diamond, CMD & DNDi are partners in the ASAP consortium, an open-science project aimed at discovering & developing new medicines against viruses of pandemic potential, including coronaviruses & dengue virus.

More about ASAP: dndi.org/research-dev... (3/3)

1 week ago 2 1 0 0
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‘Our partners @diamondlightsource.bsky.social & @cmd.ox.ac.uk are analyzing the molecular structures of around 10 new compounds most weeks. We still have a lot to do, but this is clearly the way to tackle dengue and deliver promising new drug candidates that we can advance to the clinic.' (2/3)

1 week ago 0 0 1 0
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'Every two weeks we now generate more lead‑optimization structural data on #dengue than we did in the previous two decades combined. The pace of the ASAP open-source project is astounding,' said @griffen-ed.bsky.social, technical director @medchemica.com. (1/3)

1 week ago 7 4 1 1
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Boron plays a key role in new sleeping sickness drug Acoziborole is the first single-dose treatment for both early and late stage sleeping sickness

How does acoziborole kill sleeping sickness parasites? A fascinating deep dive into the chemistry behind our new medicine, its molecular structure and its distinctive feature: a boron-based scaffold called benzoxaborole.

By @chemistryworld.com www.chemistryworld.com/news/boron-p...

1 week ago 5 3 0 0
Manufacturing medicines for NTDs, with Dr Stephen Robinson
Manufacturing medicines for NTDs, with Dr Stephen Robinson YouTube video by Drugs for Neglected Diseases initiative (DNDi)

🤔 Why are some medicines injectable, but others come as tablets? What are the challenges of manufacturing drugs for NTDs? Why is acoziborole white?

Dr Stephen Robinson, our Pharmaceutical Development Director, answers all these questions (& more) here👇
youtu.be/7KvGr_kux-E

1 week ago 0 1 0 0
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Join us for a #dengue roundtable side event to explore:
🔬 Integrated surveillance and data-driven decision-making
💊 R&D for new diagnostics, vaccines, and treatments
🤝 Regional cooperation and equitable access to health technologies

Info & registration👉 community.pasteur-network.org/events/208484

1 week ago 4 1 0 0
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For too long, pregnant & breastfeeding women have been left out of clinical studies. The @britpharmsoc.bsky.social calls to:
👉 Include them when appropriate
👉 Strengthen safety & effectiveness data
👉 Give women clear & accessible information
🔗 bit.ly/4bKA6tW

1 week ago 3 2 0 0
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Our statement at the 6th meeting of the Intergovernmental Working Group (IGWG) on the WHO Pandemic Agreement⤵️ dndi.org/statements/2...

1 week ago 0 1 0 0
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A new drug could be the beginning of the end for sleeping sickness The goal in the world of global health is to bring an end to this scourge by 2030. A new drug looks as if it could do the job.

"[Acoziborole] can dramatically simplify patient care, improve access to treatment and accelerate progress toward the elimination of sleeping sickness. It is a transformative tool," says Dr Priotto, @who.int.
Read more about our new treatment in @npr.org: www.npr.org/2026/03/16/g...

1 week ago 6 4 0 1
RD Congo : Un nouveau traitement contre la maladie du sommeil
RD Congo : Un nouveau traitement contre la maladie du sommeil YouTube video by TV5MONDE Info

One dose. No hospitalization. @tv5monde.bsky.social travelled to Kasai, DRC, to meet former patients & healthcare workers using acoziborole, our new treatment for sleeping sickness. Their reportage shows how it could transform care & help eliminate this disease.⤵️ www.youtube.com/watch?v=lz4R...

2 weeks ago 4 0 0 2
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We are very appreciative of the funding that EDCTP and many other donors and in-kind partners provided in the development of this game-changing treatment for sleeping sickness. Such long-term support makes R&D innovation possible!

2 weeks ago 1 0 0 0
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2025 R&D programmes in review: Chagas disease | DNDi DNDi and our partners are searching for shorter, safer, more effective treatments to stop a silent killer.

Great to see the progress made by @dndi.org against #Chagas disease! dndi.org/news/2026/20...

3 weeks ago 7 4 0 0
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Faire des morsures de serpent une priorité de santé publique Des experts appellent les Etats et les bailleurs de fonds à investir dans la production d’antivenins et à les rendre accessibles aux hôpitaux et patients qui en ont le plus besoin.

🐍 Snakebites affect 1.8-2.7 million people each year. The disease is deeply neglected and patients need better access to antivenoms.

A Global Snakebite Taskforce report urges on govs and funders to invest, including in R&D.

By SciDev.Net [in French]

www.scidev.net/afrique-sub-...

3 weeks ago 2 2 0 0
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In 2014, I visited eastern DRC, where @msf.org teams were treating sleeping sickness - the only available treatment was a drug so toxic it killed 1 in 20 patients. In 2026 I'm so proud that, thanks to @dndi.org, patients can be cured with a single dose of a groundbreaking new oral drug, acoziborole.

4 weeks ago 7 6 0 3
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Pandemic preparedness: Novo Nordisk Foundation renews its support to DNDi and THSTI to continue the development of broad-spectrum antivirals This grant will enable the continuation of a lead-optimization partnership initiated by DNDi and THSTI in March 2024, building on previous work that demonstrated the promise of this antiviral approach...

@novo-nordisk.bsky.social has renewed its support to DNDi and India’s THSTI to advance the development of a novel broad‑spectrum antiviral candidate targeting influenza and other viruses of pandemic potential, and strengthen pre-clinical research capacity for #pandemic preparedness.
👉 bit.ly/3N6Eo6y

1 month ago 3 1 0 0
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Dr Wilfried remembers treating sleeping sickness patients with the old medicine which was so toxic it killed 1 in 20 patients.

💊 Acoziborole is a revolution since those dark days: it cures the disease with one-day treatment course & is effective for both stages of the disease. #1Dose1Cure

1 month ago 14 6 0 1

Thank you @msf.org for your unwavering support reaching this historic milestone for sleeping sickness! 🧡

1 month ago 1 0 0 0

Thank you for sharing this great news for people affected by sleeping sickness! 🧡

1 month ago 1 0 0 0
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🚀 Huge news for people living with #sleepingsickness!

Acoziborole, a one-day, single-dose oral treatment developed with Sanofi, has received a positive opinion from @ema.europa.eu for the treatment of the most common form of sleeping sickness.

👉 bit.ly/46ZFpEi

1 month ago 22 13 2 9

Neonatal sepsis remains a leading cause of morbidity & mortality worldwide. Clinical trials like NeoSep1 Part 2 are reclaiming the narrative for newborn survival in the Global South.

👏 Congratulations @gardp.bsky.social & partners for setting a new standard for neonatal healthcare. #AMR

1 month ago 2 2 0 0
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CEPI launches global plan to secure the future against epidemic and pandemic threats The new five-year strategy—CEPI 3.0—was unveiled today as CEPI called on governments, philanthropies and partners to invest US$2.5 billion to strengthen the world’s disease defences.

Today marks the launch of the CEPI 3.0 Investment Case and Strategy.

CEPI 3.0 – our 2027-2031 strategy - is the next step in CEPI’s mission to transform the way the world tackles epidemic and pandemic threats.

Discover more in the press release ⬇️

1 month ago 7 7 1 1
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Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults Global efforts to eliminate onchocerciasis are hampered by the lack of a macrofilaricidal drug capable of killing adult parasites. Oxfendazole, a veterinary anthelminthic, exhibits macrofilaricidal a...

A Phase I study in healthy African adults assessed oxfendazole, a promising option for filarial diseases such as onchocerciasis. The findings suggest that a five day course of 400 mg daily, or 50 mg twice daily, reaches target exposure with low safety concerns. @PLOSNTDs doi.org/10.1002/psp4...

1 month ago 1 1 0 0
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The future of African public health must be collaborative, data-driven & above all, people-centred.

The recent partnership between @dndi.org & @aphrc.bsky.social will be a gamechanger in strengthening the health ecosystem at large. #HealthEquity
Read more🔗 bit.ly/4tynePW

1 month ago 1 1 0 0
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We’re at the 16th KEMRI Annual Scientific & Health (KASH) Conference 2026! Visit the DNDi booth to meet our team and learn about our work delivering safe, effective, and affordable treatments for neglected diseases. #KASH2026

1 month ago 0 0 0 0