A key stone to understand how alpha-Catenin identifies contractile forces in actin! Love it!

So amazing! Could it be engineered to produce DNA on demand?
Does it have any relationship with DNA emergence?

Cool idea! Does fluorescence appear stronger due to its reflection in the mirror?

Great unique museum! If you are a cleanliness obsessed person, don't go. So many microbes in commonly used tools 😜

Wow! At first I thought there was the tail of a second motor close by, but it folds like a long old fashioned wooden ruler!
So cool you got the bending structures!

Beautiful!

Really cool!
I don't have access but I am very curious, how did you control the nematic topology?

Cool! I guess it is not straightforward

I see you have data at multiple stages. Is it possible to morph them in a video?

So beautiful indeed! 😍

Amazing structure! 🤩

Wow! What triggers the interaction?

It's fascinating to see how motors identify different microtubules! Cool work!

They can bend so much!

Amazing work ! This will make textbook images one day.

Wouldn't it be good to compile the whole cillia morphology in a video?

Dear colleagues, With deep sadness I share the news that Andreas Engel passed away last Wednesday, at the age of 82, after a courageous fight against an aggressive caner. Only half a year ago, he was out hiking in the Italian mountains with his wife Barbara, walking 160 km in a single week. Andreas trained as a physicist in Bern, Switzerland, before heading to John Hopkins University in Baltimore for his postdoctoral work. He then led a research group at the Biozentrum in Basel, and in 1985 took on the role of a group leader in research and development at Ilford Ltd. in Fribourg, Switzerland. In 1987, he joined forces with his colleague Ueli Aebi to establish the Maurice E. Müller Institute at the Biozentrum of the University of Basel. Together, Ueli and Andreas served as professors for structural biology there for almost a quarter century, leaving a lasting mark on the field of structural biology as we know it today. Andreas Engel was a true pioneer. He was among the first to apply atomic force microscopy (AFM) with the tip operating under water, and one of the earliest researchers to perform 3D reconstructions using scanning transmission electron microscopy, achieving remarkable high-resolution maps of porin 2D crystals by STEM. He became a leading expert in membrane protein 2D crystallization, and his group played a key role in the determination of the first aquaporin structure, in collaboration with Peter Agre and Yoshinori Fujiyoshi. As he approached retirement from Basel, Andreas founded the Center for Cellular Imaging and NanoAnalytics (C-CINA) of the University of Basel, which in 2009 operated among others one of the very early Titan Krios instruments. From 2008 also held a professorship at Case Western Reserve University, Cleveland, followed by a position at TU Delft in the Netherlands in 2013. In 2020, he was among the founding members of CryoWrite, a company in Basel that he led as CEO until recently. His contributions to science, to the tools of str…

Photo of Andreas Engel

Sad news on the passing of Prof. Andreas Engel, a pioneer in the field of cryo-EM (shared with the 3DEM community by Henning Stahlberg).
Andreas' kindness, warmth, and enthusiasm for science and his colleagues will be missed.

New preprint from the lab!

How do tissue shapes influence cell fate decisions?

By manipulating brain organoid geometry, we show that lumen rounding directs apical progenitor division mode and promotes the emergence of basal progenitors.

www.biorxiv.org/content/10.6...

1/

Awesome! I remember Mami hypothesising similar outcomes!

Very clarifying and beautiful animation too! 🙌

🙌

And here is the Walk through video tutorial on how to make your proteins move with Brownian motion!

youtu.be/uOEsHBZ-omY

It's my first recording and I am not sure it is because of my stuffy nose or I always sound like this... 🫠

Do you also want to make animation with proteins moving following Brownian motion paths?

Just get my Geometry Nodes presets from: vizcie.gumroad.com/l/BlenderBro...

As soon as I have a microphone arriving and some time I will try to make a walk through tutorial ^_^

#BlenderScience #GeometryNodes

📢 Obert el Concurs #Xprimenta2026! 🧪🎥

Iniciativa de l'@fcri.bsky.social i @comunicacioaccc.bsky.social
per a alumnes i docents (de primària a FP).

El repte: explicar un concepte científic amb vídeos de màx. 3 minuts amb experiments.

🗓️Termini inscripció: 10/04

🔗Més info: tuit.cat/8fqXb

VIZCIE | Academia animation Reel March 2026 YouTube video by VIZCIE

Wanna see DNA transcription, translation, ParM filaments assembling and travel through the basement membrane of follicle cells?

Check out the reel I prepared with animations for academia.

www.youtube.com/watch?v=VMjq...

Thank you!

I'm not sure the structure holds exactly like this as long tubes. They can stack multiple turns as I saw in some publication. But not sure how it looks in the actual organism.

Archaea: The Final Frontier of Chromatin - PubMed The three domains of life employ various strategies to organize their genomes. Archaea utilize features similar to those found in both eukaryotic and bacterial chromatin to organize their DNA. In this review, we discuss the current state of research regarding the structure-function relationships of …

Learn more in this beautiful review: Archaea: the final frontier of Chromatin pubmed.ncbi.nlm.nih.gov/33383035/

PDB101: Molecule of the Month: Histones Across the Tree of Life Uncovering the evolutionary diversity of histones

I created this image for the PDB molecule of the month visualization challenge and February's topic is "Histones Across the Tree of Life" and you can find other examples at: pdb101.rcsb.org/motm/314

If the PCR method was a revolution what could give us the ability to stabilize DNA at high temperatures as archaea do?

However, none of this happens to archaea Methanothermus fervidus which thrives at 83°C in sulfur pools in Iceland. This organism compacts its DNA with the aid of heat resistant histones (shown in green in the image), and other proteins such as Alba, Cren7 and Sul7d (omitted in the image).

It is a disaster our bodies avoid by giving us the painful burning sensation.

At 83°C, the eukaryotic nucleus falls apart as scaffolding proteins collapse. Histones and other binding proteins detach from the DNA resulting in loose DNA. These unwrapped DNA strands then melt at multiple points separating into single strands that no longer keep together.