Excited to see the major chapter of my PhD in print!

We present a massively-parallel approach for screening CRISPR edits in plants to speed up agricultural test cycles + benchmark genomic LMs.

Thanks to my fantastic co-authors and advisors. Link below!

Hi, no, it is not specific to those topics but they are welcome.

We're hiring a postdoctoral researcher in plant genome engineering with expertise in synthetic biology, gene editing, and omics, with an interest in developing next-generation technologies for plants.🪴🧬

Available immediately. If interested, send your CV!

Feel free to share with your networks.

ECRs in plant–microbe interactions:

Join us in Norwich for an intensive, interactive 1.5-week Summer Conference at TSL (20–31 July). Lots of opportunities for networking and deep discussions.

(We also plan to offer hands-on practical sessions using our technologies 🔬🧬)

Interested in learning about the latest and greatest research in how plants respond to excess salt, too little or too much water? Come to the GRC in Salt and Water Stress in Switzerland. Lots of opportunities for all career levels. www.grc.org/salt-and-wat.... Please repost!

Our new review in Science @science.org is out with @jennyrussinova.bsky.social and @nvukas.bsky.social. We discuss how precise modulation of brassinosteroid signaling can enable more targeted, predictable improvements in plant growth and resilience.
science.org/doi/10.1126/science.adu9798

It was great to talk science and show @billgates.bsky.social around our lab at @caltech.edu . Nolan and Meyerowitz lab postdoc Donovan Phua's regenerating callus is featured 🌱 www.instagram.com/reel/DQo2pen...

Our cover indicates that while we celebrate the past we're looking ahead to the future - with the help of a Viewpoint!

13 researchers offer a glimpse of what their research field might look like in 2050 🔮

👉 go.nature.com/4neNdYU

A 3D-Printed Capillary Tube Holder for High-Throughput Chemotaxis Assays Bacterial chemotaxis is an important behavior to study to understand spatial segregation of species in mixed communities and the assembly of host microbiomes. This is particularly relevant in the rhiz...

4️⃣ A 3D-Printed Capillary Tube Holder for High-Throughput Chemotaxis Assays:
We developed a 3D-printed capillary tube holder that enables 384 simultaneous chemotaxis assays, making it possible to rapidly profile bacterial responses to root exudates and other chemoeffectors. tinyurl.com/3nw9haes

Vacuum and sonication treatment enables efficient transient gene expression in various monocot and eudicot plant seedlings Transient gene expression in intact plants is essential for rapidly addressing biological questions, where the current toolkit can be improved for higher efficiencies and broader plant species range. ...

3️⃣ Vacuum and sonication treatment (VAST) enables efficient transient gene expression in various monocot and eudicot plant seedlings:
A transient expression method that dramatically improves gene expression efficiency and uniformity across several monocot and eudicot seedlings. tinyurl.com/38p2ud6w

2️⃣ Optimized R2 Retroelement Complexes Enable Precise and Efficient DNA Insertion into Plant Genomes:
We engineered R2 protein to insert multi-kb DNA precisely into a safe harbor site in plants achieving 24% efficiency and 1 copy insertion per genome. Compact, precise, powerful! tinyurl.com/5n73za6h

1️⃣ Extracellular contractile injection systems for high efficiency protein delivery to plants:
We adapted bacterial PVC nanomachines to deliver proteins (Cre recombinase) to plants with 40% efficiency. DNA-free genome engineering with potential for cell-type specific targeting. tinyurl.com/mrx4d878

Big news from the Demirer lab: first 4 research papers are preprinted! Check them out, feedback welcomed:

eCIS for plant protein delivery: tinyurl.com/mrx4d878
R2 for targeted insertion: tinyurl.com/5n73za6h
Transient expression: tinyurl.com/38p2ud6w
Chemotaxis assay: tinyurl.com/3nw9haes

More ⬇️

Excited to be at #PlantBiology2025 🌱 this week and deeply honored to receive the Jane Silverthorne Early Career Award this year!
aspb.org/awards-fundi...

Let me know if you’re around and want to catch up at the conference!

#ASPB #PlantBiology2025

Excited to be speaking at Synthetic Biology Australasia 2025 in Wellington, New Zealand, 19–21 November!

I'll be sharing my group's recent advances on plant synthetic biology and genome engineering 🌱🧬

Join us:
🔗 synbioaustralasia.org/upcoming-conference
#SBA2025 #SyntheticBiology #ScienceInAction

Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits Gene circuits that control transcriptional regulation of nitrate-responses have similarities and differences, despite the equivalent effects of nitrogen on

Excited that our paper with @bradylabs.bsky.social on conservation and divergence in nitrogen regulatory networks is finally published. This was a fun & rewarding collaboration that will continue in new projects to engineer 🍅 N responses academic.oup.com/plcell/artic...

Sorghum aerial roots producing mucilage and hosting bacteria that fix nitrogen from the air

Our latest article on biological nitrogen fixation on the aerial roots of sorghum has been published in @plosbiology.org. We thank the @energygov.bsky.social for supporting this exciting project.

journals.plos.org/plosbiology/...

Join us at the 2025 International Conference on Biomolecular Engineering (ICBE) for cutting-edge discussions and an incredible speaker lineup! 🌟
Last day to register (with hotel room) is this Friday, Dec 13! #ICBE2025
🔗Register here: www.aiche.org/sbe/conferen...

🌱 Demirer Lab 🌱 @caltech.edu is looking for passionate graduate students to join us! Explore our exciting research for a sustainable future: demirerlab.com 🌏 🌱 🦠

📢 Apply here to CCE or BBE: t.co/cIv8Hbfy0Z and mention your interest in our lab in your statement.

🗓️ Application deadline: Dec 1

We’re looking for talented, driven graduate students to join our growing Chemical Engineering Ph.D. program at @caltech.edu!

⏰ Applications are due December 1, 2024.

➡️ Apply Here: t.co/cIv8Hbfy0Z

Hello new Plant Scientists,

2 Things:

👉 To connect to 150 Plant Science Accounts and 3 relevent feeds, here's a #StarterPack for you:
go.bsky.app/8Zfmwf7

👉 To get your #PlantScience posts into the Plant Science Research Feed (here: bsky.app/profile/did:...), always use the Hashtag #PlantScience

We made it to Orlando for the #AIChE2023! This is Mark’s @mlegendr.bsky.social debut to the AIChE community!! Check out his poster (#111) on Monday 3:30 pm discussing our recent work on genetically encoded delivery vehicles for plants 🌱