Gail R. Martin (1944–2026): Embryonic stem cell pioneer, developmental biologist, and student of Asian art and ceramics | PNAS Gail Roberta Martin, Professor Emerita of Anatomy at the University of California, San Francisco, and one of the founding figures of modern stem ce...

A very moving tribute to one of the founders of modern Stem Cell Biology: Gail Martin.
Well worth a read.

www.pnas.org/doi/10.1073/...

it's rarely brought up that the need to slap fake bylines on AI content is a tacit admission that no one wants to read it

Image Analyst (Core Bioinformatician) Van Andel Institute (VAI), a world-class biomedical research institute, located in Grand Rapids, Michigan, is dedicated to improving human health. We are pioneers in the fight against cancer, Parkinso...

We are still accepting applications for an image analyst within the Optical Imaging Core at Van Andel Institute. If you know anyone that is looking for a career in image analysis, please encourage them to apply!

vai.wd1.myworkdayjobs.com/en-US/VAICar...

Did you know Scott Fraser will be at the Santa Cruz Dev Biol meeting? He's President of Dynamic Imaging and Head at the Chan-Zuckerberg Initiative BioHub, and a developmental biologist! He'll speak about his 40 years at the interface of academia, industry, and philanthropy.

scdb2026.sites.ucsc.edu

Reminder that on Thursday, I will be talking about zebrafish, neurons, genes, transcriptomics, patterning, stochasticity, and everything in between! 🧪🐟 B.Y.O.F

Alexa: what is dystopia?

sure it's a tool of social control and surveillance owned and operated by fascists, but it writes work emails for me. on balance who's to say it's good or bad

Real ones know why I love NIST with all my heart.

Early Career Faculty Program | Freeman Hrabowski Scholars | HHMI The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...

@hhmi-science.bsky.social's
#FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits

Stable, sustained support can transform your career:

Senior Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

Wondering why a technology that is inevitable needs to influence election outcomes?

I will try to be happy for JHU and their good fortune.

Friday was my last day at NHGRI. After 10 wonderful years, my lab is headed to Johns Hopkins University
genomeinformatics.github.io/movingday/

For U.S. medical researchers, shrinking labs and bare budgets are the new reality The Trump administration has slashed the number of grants from the National Institutes of Health, with far fewer focused on women, cancer and mental health.

Bhattacharya, Letai & other politicals at NIH keep trying to to say all at NIH is fine, because they spent the full budget last year. This well researched article from @carolynyjohnson.bsky.social explains exactly why many scientists are still struggling. www.washingtonpost.com/science/2026...

Liver morphology and NAFLD progression in humans and zebrafish. (A) Zebrafish have a similar anatomy of the digestive system compared with humans. Tissue pathological processes can be studied for metabolic associated liver diseases. (B) The progression of NAFLD in humans and zebrafish. Lipid accumulation in the liver caused by obesity, insulin resistance and other factors leads to steatosis. Increased inflammation and oxidative stress promote NASH, and immune escape and fibrosis further lead to liver cirrhosis and even HCC. HCC, hepatocellular carcinoma; NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis. Image and text from Chang et al. (2023) Liver International

Today is #WorldLiverDay! Did you know #zebrafish have livers that function & develop hepatocellular carcinomas similarly to human livers? Researchers leverage the zebrafish model to understand & develop novel treatments for liver disease. Learn more: pmc.ncbi.nlm.nih.gov/articles/PMC... #KnowYourZDM

mRNA technology may be THE most underrated and unfairly scrutinized (fuck you COVID antivax crew) medical breakthrough in my lifetime.

Like... The things this is already showing it can do in the last 5-7 years is incredible.

A Newly Discovered Recording Lets You Hear Delta Blues Legend Robert Johnson in Stunning Clarity Great swathes of rock music since the nineteen-sixties would never have existed, we're sometimes told, were it not for the recordings of Robert Johnson. Certainly the likes of Keith Richards, Eric Cla...

Holy SHIT someone found the test pressing of Robert Johnson's Cross Road Blues and it is clear as a PIN www.openculture.com/2026/04/reco...

I spend most of my time doing very basic research, but I am at a symposium to honor Dan Kastner whom I’ve had the opportunity to collaborate with a couple times. It is jarring to see actual patients with diseases my lab helped model in zebrafish and makes me a little proud we could help.

Streaming Love Island.

It’s not the inconvenience people long for. It’s a longing for consistency, reliabiliy, and simplicity, appreciation for things that are truly *yours* once you buy them, and being EXTREMELY sick of black boxes, forced obsolescence, product-as-service, and never knowing if the next update is going…

It also occurs to me that something people need to start talking about more is that a great deal of modern tech ISN’T convenient. Being bombarded with ads is inconvenient. Paywalls are inconvenient. Forced broken AI is inconvenient. Constant unwanted updates are inconvenient. Being unable to fix…

We are not the same.

4th Canadian Zebrafish Research Community meeting Join 4th Canadian Zebrafish Research Community meeting, May 15, 2026. Learn more on Fourwaves.

🐠 Deadline extended!
We’re extending the deadlines for the 4th Canadian Zebrafish Research Conference (CZRC) in Montréal 🇨🇦

📝 Abstract submission: April 24
🗓 Registration: May 1

Submit for talks, posters, travel awards & Postdoc Rising Stars!

US lawmakers intensify scrutiny of scientific-publishing practices A congressional hearing covered the rise of paper mills and the costs of open-access publishing — but there was little agreement on what reform would entail.

In a rare show of unity, both R and D US lawmakers agree: the scientific publishing industry needs reform.

Lawmakers are worried about the literature being flooded with 'AI slop' and the high open-access fees that some publishers charge.

Read more @nature.com on this week's House Science hearing

One of the things I learned in science is that as soon as something gets easier, expectations increase to compensate. From that you can extrapolate that there is no such thing as a time saving device. *looks directly into AI camera*

The Rush hour (Rush hour of glucose utilization early in the light phase when glucose if funneled into multiple biosynthetic pathways). Human (left) and fly (right), either side of a schematic showing 13C-Glucose feeding into glycolysis, pentose phosphate pathwat or TCA cycle, over a watercolour wash. Image credit Pinky Kain.

How do #circadian clocks regulate glucose processing? By integrating human metabolite profiling with isotope-tracing in #Drosophila, this study defines daily rhythms in #glucose utilization that are influenced by circadian timing @plosbiology.org 🧪 plos.io/3Olm1M1

🔈 Heading to Euro Evo-Devo #EED2026 in Glasgow? Don't miss out our Fish Satellite Meeting! Co-organized with Mike Dorrity @mwdorr.bsky.social, Ralf Schneider @ralfschneider.bsky.social, Laure Sanders @lsaunders.bsky.social and Joost Woltering, and with a list of outstanding speakers 👇

Always a good reminder that celebrities don’t have special insight or wisdom about anything other than the particular art/industry they’re famous in. Don’t take their advice about finance, medicine, AI, nfts, or whatever random novelty they shill next.

4/ Meet Hydra: a tiny organism w/ extraordinary regeneration powers. Awardee @julianolab.bsky.social will study how they rebuild their nervous system after injury - what she uncovers could change what's possible for neural🧠 repair.
🍾 Congrats Dr. Juliano! @ucdavis.bsky.social
🙏 #HFScout Ellen Yeh

Fig. 1. Early expression of TgBAC(ankrd1a:EGFP) transgene in the border zone CMs. Hearts of TgBAC(ankrd1a:EGFP);Tg(−0.8myl7:nls-DsRedExpress) (n = 4) were cryoinjured and left to recover for 6 and 15 h. White dashed line outlines the ventricle. Scale bars, 200 μm.

Fig. 6. Persistent TgBAC(ankrd1a:EGFP) expression in CMs adjacent to the residual scar. Hearts (n = 4) of TgBAC(ankrd1a:EGFP);Tg(−0.8myl7:nls-DsRedExpress) zebrafish were cryoinjured and analyzed at 30 dpci, showing different levels of scar resolution (least (A) to most (D) regenerated). The whole hearts after dissection were imaged by fluorescence microscopy (A-D). Serial sections were used for AFOG staining (bright-field images on panels А'-D′) and fluorescence imaging by confocal microscopy (А"-D″). In the indicated region of injury on panels A'-D′, collagen is stained blue, fibrin is stained orange, and CMs are stained brown. Scale bar, 100 μm.

An interesting paper from the Kojic lab shows that ankrd1a - a stress responsive gene is consistently unregulated near damaged site in the ❤️ in zebrafish. Loss of ankrd1a leads to an increase in dedifferentiating cells. Check it out here:
doi.org/10.1016/j.cd...