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Posts by Edna Ondari

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Salmonella-derived haem inhibits macrophage phagocytosis and promotes infection in mice - Nature Microbiology SirM methyltransferase upregulates Salmonella HemL-dependent haem production to enable haem-dependent inhibition of phagocytosis and promote infection in mice.

www.nature.com/articles/s41...

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We’re Training Scientists for a World That No Longer Exists - Science Politics Science can help address pressing challenges, but only if we train scientists to communicate in the places people actually form beliefs.

sciencepolitics.org/2026/03/18/w...

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People living with HIV age faster, but antiretroviral therapy can help: New study Researchers say this finding could transform how clinicians monitor HIV treatment and long-term health outcomes.

New study: People living with HIV age faster, but antiretroviral therapy can help.

Researchers say this finding could transform how clinicians monitor HIV treatment and long-term health outcomes.

Read more about the study and its findings: ow.ly/NIOI50YN3yX.

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Image of a newborn in an incubator.

Image of a newborn in an incubator.

Antibiotic-resistance genes were detected in babies within their first 3 days of life.

Researchers say the study, presented at ESCMID Global 2026, is the largest of its kind on antibiotic-resistance genes in the neonatal gut.

Read more: ow.ly/Q8o250YMUtc

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Immunological memory to vaccines The generation of immune memory is at the crux of vaccine efficacy. Here, Crotty reviews the layers of adaptive immunity—T cell, B cells, and antibodies—and their integration to generate a holistic view of vaccine response. Common misconceptions and questions in the field are also highlighted to guide future vaccine considerations.
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Quick takes: California urges mpox vaccination, UK menB campaign, Legionnaires' in North Carolina The first travel-related case of clade 1 mpox haas been identified in San Francisco.

Quick takes:
-California urges mpox vaccination
-Vaccines and antibiotics offered to young people in Dorset following 3 recently confirmed cases of meningitis B
-More reports of Legionnaires' in North Carolina

Read more: ow.ly/tZwY50YN09T.

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Scientists stunned by ‘fundamentally new way’ life produces DNA Newly discovered bacterial defense system challenges genetic code’s central dogma

www.science.org/content/arti...

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Gout Gout, 18, breaks Usain Bolt's under-18 200m record with 19.67 seconds - Australian sprinter from Brisbane is the new fastest teen on Earth

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Person functionally cured of HIV after bone marrow transplant from sibling A man with HIV has gone into remission after receiving bone marrow from his brother, who has a rare mutation that prevents the function of receptors that HIV binds to

A man with HIV has gone into remission after receiving bone marrow from his brother, who has a rare mutation that prevents the function of receptors that HIV binds to

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DETECT (@advance-id.bsky.social, Singapore) is conducting a global survey to assess gaps in clinical microbiology diagnostics. If you’re a lab manager, senior lab staff, ID physician, or expert in your facility’s diagnostic workflows, the team wants to hear from you! #IDSky 🧪

🔗 bit.ly/4dxdDDs

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Image of a woman sitting down with her head propped up on her hand, looking into the distance.

Image of a woman sitting down with her head propped up on her hand, looking into the distance.

Long COVID costs Organisation for Economic Co-operation and Development (OECD) countries up to $135 billion each year.

A report last week by the OECD projects that long COVID’s significant social & financial costs will continue well into the next decade. ow.ly/e35t50YIuaX

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Disappointing but important news in TB vaccine research.
A large phase 3 trial (~12,700 participants, 38 months follow-up) testing VPM1002 and Immuvac in household contacts of TB cases did not show meaningful protection against pulmonary TB, the form that drives transmission.
#IDSky #MedSky

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Very sad yet completely unsurprising to see data censorship of a study showing the positive benefits of the COVID vaccines in preventing hospitalizations. This is anti-science in action and also harmful to public health. I expect better from the NIH/ acting CDC director but alas.

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Interspecies competition promotes antibiotic resistance with diminishing returns Evolutionary outcomes are affected by multiple complex factors, many of which are omitted from traditional experimental designs. In their recent manuscript, Muzafar et al. demonstrate that interspecie...

www.cell.com/trends/micro...

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This is tough news

For herd immunity, measles vaccine coverage needs to be much higher (95% or higher)...

So, outbreaks will occur

I hope B.C. can step up and turn things around

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Mpox emergence, epidemiology, biology, clinical features and control Nature Reviews Microbiology, Published online: 08 April 2026; doi:10.1038/s41579-026-01305-yIn this Review, Ogoina et al. examine the emergence of mpox and its epidemiology, the viral life cycle, transmission dynamics, risk factors and clinical characteristics. They also explore current and future prevention and control strategies, including the therapeutic and vaccine landscape, as well as the urgent need for integrated surveillance, equitable access to countermeasures, and Africa-led research to address the ongoing multi-clade threat.

New online! Mpox emergence, epidemiology, biology, clinical features and control

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Image of healthcare worker in gown and gloves.

Image of healthcare worker in gown and gloves.

New data show C difficile incidence in hospitals fell during the COVID-19 pandemic. ⬇️

Researchers say the reduction was influenced by the combined effects of changes in infection prevention & control, antimicrobial stewardship, & health care delivery. ow.ly/xc7p50YF783

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Fatty acid biosynthesis inhibitors fabimycin and triclosan trigger distinct resistance mutations in FabI and potently kill Gram-negative pathogens www.biorxiv.org/content/10.64898/2026.04...

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imagine if i happened to be a trillionaire and bought twitter and 80% of the stuff on the site was just about big pants. you couldn't escape it. just an endless deluge of big pants propaganda

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You know what, the world finds a way to keep advancing

Even as measles outbreaks are raging across Global North countries, fueled by disinformation, Institut Pasteur de Dakar in Africa has developed the world’s first rapid test for measles!

Bravo! @pasteur.fr @institutpasteur.bsky.social

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Antimalarial efficacy monitoring after nearly 20 years of artemisinin-based combination therapy in Africa: recalibrating guidance Timely identification of resistance to antimalarials is necessary to ensure effective malaria case management. The backbone of antimalarial resistance surveillance strategies is the therapeutic efficacy study (TES). Originally designed to be easily deployable, in recent years, TES have become increasingly complex and slow to yield results. Concurrently, advances in molecular surveillance techniques, the emergence and spread of artemisinin partial resistance in Africa, and advances in antimalarial drug stewardship through multiple first-line therapies have changed the context in which TES are implemented. In this opinion article, we outline considerations for recalibrating TES methodology. More efficient TES, coupled with molecular surveillance, could provide timely and actionable data for malaria-endemic countries as they manage treatment policies in the context of drug resistance in Africa.

Antimalarial efficacy monitoring after nearly 20 years of artemisinin-based combination therapy in Africa: recalibrating guidance

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Chikungunya virus persists in joint-associated macrophages and promotes chronic disease in mice @natmicrobiol.nature.com
www.nature.com/articles/s41...

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Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota Rogers et al. show that Salmonella overcomes colonization resistance when the microbiota is compositionally intact by disrupting epithelial hypoxia. Pathogen outgrowth is fueled by catabolizing simple...

www.cell.com/cell-host-mi...

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Filling the Gaps: A Review and Update on Beta-Lactamase Inhibitor Combinations - Current Infectious Disease Reports Purpose of Review Gram-negative antimicrobial resistance continues to pose a growing threat, particularly among high-priority pathogens such as difficult-to-treatPseudomonas aeruginosa, carbapenem-res...

link.springer.com/article/10.1...

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WHO Releases New Targets to Guide Development of Antibiotics for Drug-Resistant Infections | Contagion Live The World Health Organization has released 3 new target product profiles aimed at guiding the development of urgently needed antibiotics for severe drug-resistant infections, including multidrug-resis...

www.contagionlive.com/view/who-rel...

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Antimicrobial resistance: a concise update Antimicrobial resistance (AMR) is a serious threat to global public health, with approximately 5 million deaths associated with bacterial AMR in 2019. Tackling AMR requires a multifaceted and cohesive...

www.thelancet.com/journals/lan...

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Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics - Nature Microbiology Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. This study presents an approach to systematically discover and ...

www.nature.com/articles/s41...

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During a 2023 polio outbreak in Zimbabwe, vaccine misinformation spread via WhatsApp groups and threatened to derail the health response.

Sensational disinformation can quickly go viral with the potential to endanger lives.

Here’s how health teams worked to rebuild trust: bit.ly/4d78NfS

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