Direct observation of conformational dynamics of intrinsically disordered proteins at the single-molecule level Intrinsically disordered proteins (IDPs) and proteins with intrinsically disordered regions (IDRs) are integral to many biological processes, including neurotransmitter regulation, microtubule regulat...

Very excited to have played a small part in this work out on biorxiv now.

www.biorxiv.org/content/10.1...

Saaman shows optical trapping of single intrinsically disordered proteins and how that can be used to understand the conformational and binding dynamics with no labels!

Congratulations!

My biggest complaint about Switzerland

In my spare time I've been making a GUI for single protein optical tweezer analysis (as coding practice and to help standardize the technique). If you have any tips or features you think are important to add I'd be glad to hear them!

Currently adding our custom state recognition algorithm too