My first paper w/ Matt, about how mRNA and protein levels of the same genes should be expected to coevolve. It was carried over from my PhD at Michigan w/ George Zhang, but started too late to be in my thesis.
academic.oup.com/mbe/article/...
Maybe not the best phylogeny to use to explain homology. So this pair o' logs are orthologs, but if they arose via duplication and you can recover synteny for one, you could call it a syntelog and the other single log a paralog."
The long-awaited FLASH manuscript is finally out--check out some interesting results on predicting drug resistance in C. tropicalis, C. auris and other yeasts using a unique k-mer based model! www.biorxiv.org/content/10.6...
Still mourning #fungal26? Want to celebrate the release of the April 2026 edition of G3? Why not give this a gander? We found impact of low level contamination on population analyses in both Saccharomyces cerevisiae and Aspergillus fumigatus! #mycosky #academicsky
hype video does have me feeling a type of way despite knowing our next game is v montreal so maybe… maybe we WILL win that one… could be fun! could be VERY cute of us #pwhl #weewoo
yes but let’s not talk too loudly about it it’s upsetting me
really feeling the kalty shaped hole in our line tonight :( hoping the undisclosed, out day-to-day injury is not too serious because the sirens need her back #pwhl #weewoo🚨
Hi all. I am very excited that after 6 years I finally got my phylogenetic comparative methods book and online exercises online. Feel free to use and share. The book is here: nhcooper123.github.io/pcm-primer/. Note that it is not finished, we had to abandon it before the sunk costs fallacy broke us
back from conference! good news: inspired 💡, better idea of how to approach some protocols, experiments to add to research plan for a more complete vision 🥼
bad news: inspired 🌟🕶️, have to rework research plan to incorporate experiments 🧬🧪, steak too juicy 🥩, lobster too buttery 🦞🧈 #academicsky
#Fungal26 need something to read on the flight home? Now obsessed with tRNAs? New Preprints!
Genes near tRNAs are enriched in translational machinery:
tinyurl.com/zshnf835
Hidden Diversity in Yeast tRNAs: Comparative Genomics and Modification Mapping in a Eukaryotic Subphylum
tinyurl.com/3j6f3up2
What a way to end #fungal26
We laughed and we cried and we learned so much
A great reminder to look back and reflect on the past
It can light the way to the future
Thank you Nancy Keller for being a light 🕯️ in the field
Image from Claude ai
Shout out to the myco-skeeters 🦋 at #fungal26
It's been fun live posting with you!
@germhuntermd.bsky.social @talbotlabtsl.bsky.social @audreykward.bsky.social @angusb.bsky.social @hyphaltip.bsky.social @uehlinglab.bsky.social
Environmental genomes of Coccidioides hold potential for tracing human infections Lisa Couper, Molly Radosevich, Kaylee Christensen, Mark Bitter, Katharine Walter, John Taylor, Justin Remais, Rachel Brem Berkeley
Next talk in our #fungal26 session on emerging fungal pathogens is Dr Lisa Couper on genomes of environmental isolates of Coccidioides for tracing human infections
Communication continues! Baoye He shares how cross-kingdom 🍄🌱 communication happens with extracellular vesicles 🫧 and RNA trafficking 🚛🧬 #fungal26
Travis Seamons invites us to 👂 listen into some microbial conversations using RNA Addressable Modification 🧬 and barcoding. (Read more here: www.nature.com/articles/s41...) #fungal26
No RNAi, big problems 🧬➡️🛑 Mycoviruses 🦠 interfering with RNAi can make fungal pathogen Cryptococcus neoformans more virulent in mouse models. 🐁😷 Fascinating talk from Jun Huang. #fungal26
Cook your morels and avoid painkillers at night- fungal wisdom at #Fungal26
Jasmine Ono (@jtono.bsky.social) discussing some matchmaking mechanisms gone wrong 😱 💔
Saccharomyces paradoxus and Saccharomyces cerevisiae F1 hybrids are sterile largely due to recombination rejection 🛑✋🏻 due to mis-segregation of chromosomes 🧬➡️❔🤷♀️ #fungal26
María Angélica Bravo Núñez uses natural isolates of Saccharomyces cerevisiae 🌳🧫 to understand how aneuploidy and structural variation 🧬🧱 changes over time.
Take home message (with some of my own soapboxing): don’t just rely on lab strains - look for natural variation in the wild! 🏕️🍇 #fungal26
Hanne Griem-Krey discussing ✨🚀 Starship-mediated horizontal gene transfer 🧬➡️🧬 of transposable elements in the insect pathogen 🐜😷 Metarhizum anisoplaie. #fungal26
Hey #Fungal26 attendees, vote for your next Fungal Genetics Policy Committee through the conference app! These folks work with @genetics-gsa.bsky.social to organize your conference 🍄
Lluvia Vargas Gastélum shares the fractured 💔 genome 🧬 of the Basidiobolus
Why are there so many chromomes!? Could it be the LINES near telomeres?
#fungal26
Emile Gluck-Thaler elucidating the mysteries 🔎 of fungal variation and phenotype using 🚀✨ Starship transposon framework. How do these 🔗 link to and impact fungal evolution? #fungal26
Really, really fascinating talk from the Tsai lab (@ishengtsai.bsky.social) about the fungi Acrodontium living in the mucilage of the carnivorous plant 🪰🪴 ☀️ Drosera - and how it promotes prey digestion! 🍴#fungal26
@evelinesnelders.bsky.social shares work utilizing citizen science 👥🥼🧪 to sample for airborne fungal resistance with Schimmelradar (fungal radar) program 🍄📡 - and some really cool results showing land use is a better predictor for azole resistance! 💪🏻 #fungal26
@lablabella.bsky.social labmate Caroline West sharing some collaborative work with the @morgancarterphd.bsky.social lab exploring 👀💻 codon usage patterns in R. microsporus, its bacterial endosymbiont, and the phages within the bacteria! 🦠🧬🧪 #fungal26
Jack Gregory explores the diversity of endohyphal 🍄 bacteria 🦠 of clinical samples of Mucorales
He searched 🔎 in WGS data for Mycetohabitans DNA 🧬
Then took that approach to clinical 🏥 samples
#fungal26