Now published in NAR. Thanks to the editor and reviewers who provided a great review experience which certainly improved the paper.
urldefense.com/v3/__https:/...

Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression The EMF-inducible gene switch (Ei) platform provides precise spatiotemporal control of gene expression through Cyb5b-mediated calcium oscillations. This system enables Ei-OSK-driven in vivo rejuvenati...

This is mind blowing!

www.cell.com/cell/abstrac...

Check out this new preprint from our lab. Kudos to Huizi!

Yes, ants are amazing.

www.biorxiv.org/content/10.6...

Poster for the Max Planck Freiburg 8th Epigenetics Meeting from 2 to 4 December 2026 listing speakers, keynote, registration details, and contact information on a dark blue background with yellow and white text

The 8th Epigenetics Meeting is coming — Dec 2–4, 2026, Max Planck Freiburg.

27 top speakers. Chromatin biology, epigenetic regulation, and real conversations. And you☝️!?

Registration is open. Don't wait. 👇
🔗 events.ie-freiburg.mpg.de

I’m happy to announce the first US-based international meeting on epigenetic inheritance, taking place July 15–17, 2026. Registration is now open! Join us for an exciting program featuring outstanding speakers and cutting-edge research. Please share and spread the word! #EpigeneticInheritance2026

Mega congrats Diana!

a woman in a purple scrub top says " yes ! i did it " Alt: a woman in a purple scrub top says " yes ! i did it "

I am thrilled to announce that the Voss Lab will be opening for business Fall 2026 in the Department of Biology @mtsuofficial.bsky.social! It's been a long journey & I am so happy to finally find my scientific home. 🫀🧬🧪
#newPI #womeninstem #AcademicSky

(And yes, we're hiring!)🥼

A deep dive without first defining what they mean by #epigenetics.

But that's OK, nice thought-provoking ideas.

Gedankenexperiment: if you replace the word "epigenetics" throughout with "transcriptional regulation", now how does it look?

Join us: Seminar by Alessandro Scacchetti – Tuesday, 31st March at 11:00 am @metalsga.bsky.social @upenn.edu

There has never been a better time to study functional and mechanistic biology at the organismal (!) level than now in the age of AlphaFold and CRISPR.

Another amazing piece of work from the Conine lab!

Happy St. Patrick's Day, New York.

A strong weekend and a great result for the team! 💪

👀

Image from their link showing evidence of fabricated references

Holy smoke. What ultimately happened???

Must read!

www.biorxiv.org/content/10.6...

finally!

Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila - Nature Genetics Pico-C, a low-input Micro-C approach, reveals that dynamic three-dimensional genome folding precedes zygotic genome activation in Drosophila.

Excited to share my PhD work!

The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development.

Here’s a quick Blue-torial 🙂 (1/n)

www.nature.com/articles/s41...

A retroelement-derived mammalian ARC protein exhibits selective RNA recognition and nucleic acid chaperone functions - PubMed Activity-regulated cytoskeleton-associated protein (ARC) is an RNA-binding protein that also serves as a central hub for neuronal protein-protein interactions. It is essential for intercellular signaling and contributes to synaptic plasticity. ARC includes Gag-like sequences of Ty3/Gypsy retrotransp …

#TEsky A retroelement-derived mammalian ARC protein exhibits selective RNA recognition and nucleic acid chaperone functions pubmed.ncbi.nlm.nih.gov/41797537/

YESS Charles Leclerc
!! A podium to kick off 2026! 🏆

Deltaviruses spread through a viral Trojan Horse Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expr…

We found a viral Trojan Horse: a virus can hide inside another virus.This one surprised us: deltaviruses don’t just borrow a helper virus. They can travel inside it.
A literal Trojan Horse “virus-in-a-virus” route into cells. 🤯 Kudos to 1st author @viroscope.bsky.social and co-authors !

Pseudouridine selects RNAs for extracellular transport www.biorxiv.org/content/10.1...

Also, I am moving back to Europe and I'm looking for a job :)

17/
I’d like to thank everyone involved—labmates, collaborators, and especially Roberto, who gave me the opportunity to pursue this “wild” project and supported me every step of the way.

16/
The genetic identification and biochemical validation of this and other mechanisms governing exRNA selection will help uncover the biological functions of extracellular RNAs and ultimately decode the language of RNA-mediated cell-to-cell communication.

15/
In summary, we uncover a pathway for RNA secretion, whereby PUS1 catalyzes the formation of Ψ on select RNAs, marking them for export through recognition by MYL6.

14/
So how might Ψ drive exRNA export?

One possibility is that RNA-binding proteins recognize Ψ-marked RNAs and channel them into secretory pathways.

Surprisingly, we found that MYL6 (myosin light chain 6) selectively binds Ψ-containing exRNAs and is required for their extracellular transport.

13/
But is Ψ also necessary?

PUS1 depletion causes loss of Ψ at hundreds of RNA sites. Importantly, export of RNAs carrying PUS1-dependent Ψ is the most strongly affected.

12/
Interestingly, Ψ appears sufficient to promote secretion, at least when introduced into synthetic RNAs.

11/
Because PUS1 is required for the release of some exRNAs, we hypothesized that its catalytic product (Ψ) might promote RNA export.

By adapting LIDAR to detect Ψ genome-wide, we found that exRNAs carry higher levels of Ψ than intracellular RNAs, suggesting a link with secretion.