Coooooool beans !! 😁 Congrats to all !

💥finally here💥. Our latest manuscript (@goetzjacky.bsky.social lab) is out in @natmater.nature.com. We show that cell viscosity drives the metastatic potential. A project handled by former PhD student Valentin Gensbittel, help from Zeynep Yesilata & many labmates! www.nature.com/articles/s41...

Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers - The EMBO Journal The rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these events under flow conditions. Here, we developed an i...

Delighted to share the latest paper from the lab
"Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers"

Amazing work driven by @follainga.bsky.social with contributions from many.

link.springer.com/article/10.1...

Our newest paper is out in NCB. @jrwconway.bsky.social‬ designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41...

New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...

Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers Leukocyte extravasation is a key component of the innate immune response, while circulating tumor cell extravasation is a critical step in metastasis formation. Despite their importance, the mechanism...

www.biorxiv.org/content/10.1...

Can't wait to be in Italy for GRS/GRC...! 🥶
Fibronectin, Integrins and Related Molecules
www.grc.org/fibronectin-...
I'll present our preprint and more on extravasation of PDACs. :)

We wrote a small Viewpoint for Molecular Oncology with
@follainga.bsky.social

@omkarjoshi.bsky.social

Michal Dibus

via EACR
@helloeacr.bsky.social

Time, the final frontier
febs.onlinelibrary.wiley.com/doi/full/10....

Hope you find it interesting

Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers Get started with Beautiful.ai today.

Trying something new: For our recent preprint:

Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers

www.biorxiv.org/content/10.1...

I made an online presentation:
www.beautiful.ai/player/-ODGe...

Ivaska cell adhesion and cancer Lab Integrins, matrix, motility and mechanotransduction in cancer

Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fi