A powerful electrical motor propels bacteria in virtually every gut and puddle on Earth. After 50 years, it has finally been understood. @nattyover.bsky.social reports: www.quantamagazine.org/what-physica...
A young ascidian.
Sea squirts can often look like leathery sacks, fine vases, or soft crusts, siphoning water in and out of their bodies and extracting the oxygen and nutrients.
Lately I've been thinking a lot about science, scicomm, and the crazy world we live in.
And yeah. Now I'm completely reworking my newsletter.
Because I feel like us science folks — scientists, scicommers, journalists, everyone who believes in science and truth as a force for good — need to talk.
I spend most of my time doing very basic research, but I am at a symposium to honor Dan Kastner whom I’ve had the opportunity to collaborate with a couple times. It is jarring to see actual patients with diseases my lab helped model in zebrafish and makes me a little proud we could help.
🪱 Serving head-to-tail fluorescence 💅 Whole-animal FISH in the planaria Schmidtea mediterranea: 🔵 Head 🟣 Gut 🟡 Tail ✨ Masters of regeneration and color coordination 📸 Image from Viraj Doddihal #FluorescenceFriday
To be featured submit your images here ➡️ forms.gle/PWyaViekkNNn...
Check out our story online now in Science!
We tracked a zebrafish tail tip for 30h of light-sheet imaging.
It didn’t exist at t=0.
LiLiTTool: CoTracker3 + object detection → real-time microscope steering.
3D, multi-ROI, open source.
www.biorxiv.org/content/10.6...
#bioimaging #lightsheet
thanks @jytinevez.bsky.social
#ZebrafishZunday but make it Easter-themed? You got it! 🐟🥚 Cytoplasmic streaming inside of a zebrafish oocyte. Credit to @shamipourshayan.bsky.social & @heisenbergcplab.bsky.social 🔬🐟 🧪
Excited to share our latest work with Guanming Zhang and @stemartiniani.bsky.social in @natcomms.nature.com, where we uncover universal long-range structure in three distinct noisy particle systems spanning soft matter and machine learning.
www.nature.com/articles/s41...
Within the field of transcription, the distinctive style of Mark Ptashne and Kevin Struhl stands out.
At his best, Kevin Struhl provides a valuable clarification of the relationship between promoters and enhancers in the regulation of transcription.
www.annualreviews.org/content/jour...
Now #published @prxlife.bsky.social: a great Dresden collaboration on lumen mechanics with @chandraniva.bsky.social @markusmukenhirn.bsky.social, Alf Honigmann @biotec-tud.bsky.social @poldresden.bsky.social!
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
Thread 21: Hox genes (focusing on their role in the rhombomeres)
From both the Bianchi textbook and from my notes on my biology advisor's 2024 graduate dev bio class.
(1/n)
Deadline is approaching (April 16th). Send in your applications . All details here: www.janelia.org/you-janelia/...
Apply for this workshop at @hhmijanelia.bsky.social
intended as a "by the students, for the students" meeting.
@janeliaconf.bsky.social
Time to share some data that might get buried in the supplement of our recent paper here rdcu.be/e91Kj
Here you can see how cells intercalate in a coordinated fashion. They move from a double rowed organisation to a single row stalk. 🧵
Delighted to share my pedagogical article where I introduce active soft condensed matter and its relevance to the biological sciences in clear, accessible language.
Grateful to the Resonance editorial team for the opportunity.
www.ias.ac.in/describe/art...
Did you think that small gene regulatory networks are only capable of very simple dynamics? Guess again! Even very simple networks are capable of a rich dynamics. Check out our brand new review paper: www.sciencedirect.com/science/arti... @perez-carrasco.bsky.social
But with no less love and insight has the science of Form and Number been appraised in our own day and generation by a very great Naturalist indeed:—by that old man eloquent, that wise student and pupil of the ant and the bee, who died but yesterday, and who in his all but saecular life tasted of the firstfruits of immortality; who curiously conjoined the wisdom of antiquity with the learning of to-day; whose Provencal verse seems set to Dorian music; in whose plainest words is a sound as of bees’ industrious murmur; and who, being of the same blood and marrow with Plato and Pythagoras, saw in Numbe“rl a clef de la voute,” and found in it “le comment et le pourquoi des choses.”
I've been reading D'Arcy Thompson's "On Growth and Form" (1916) and boy could he write!
Pictured are cross sections of larvae from Nematotstella (left) and Aiptasia (right), with the sliders underneath representing the mechanical modules which combine to give rise to an organism's mechanotype. Credit: Daniela Velasco/EMBL
A sea anemone looks very different from a coral, despite belonging to the same broad biological group.
A new study from EMBL researchers and their colleagues sheds new light on how diversity arises in body shapes in the animal world.
www.embl.org/news/science...
Excited to share my first PhD project: LabConstrictor 📒🐍
Have you ever created a Jupyter notebook with all your love 🫶, only for others to be unable to install it 🥲? LabConstrictor, comes to solve this!
Check out how it works in the preprint 🔗 arxiv.org/abs/2603.107... or follow this thread ⬇️
How do pairs of DNA loci - such as enhancers and promoters - find each other inside the nucleus? 🤔
Most models assume the random forces driving locus motion are independent in space
New preprint by
@janniharju.bsky.social: this assumption fails in living cells 🧵
www.biorxiv.org/content/10.6...
YEN 2026 registration is now live!
Join us for the 2026 YEN conference on the 15th of June at the Francis Crick Institute, London, UK.
Sign up now to attend and submit your poster/abstract: forms.gle/2HQEmZgEi4hP...
Abstract submission deadline is 15 May.
Stay tuned for more information!
Oscillations, like radio waves, can encode multiple dimensions of information. @sonnenlab.bsky.social studies oscillation dynamics in different stages of development. In the early embryo, Hes1 gene oscillations are predictors of cell fate. #gfe2026
Read a recent @dev-journal.bsky.social article⤵
Excited to share my PhD work!
The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development.
Here’s a quick Blue-torial 🙂 (1/n)
www.nature.com/articles/s41...
I am thinking about Descriptive Geometry today - its history, culture, my approach, and my pleasure in practicing an allegedly outdated craft:
New blog post:
elkement.art/2026/03/10/o...
Calling for protocols on The Basics: get a protocol recorded and peer reviewed, and help a colleague learn the tips and tricks by *seeing how it's done*
You don't need to include new results and it does not have to be your original protocol. Just cite well and share the know-how 💕🔥
Get in touch!
Cellquant: a vibecoder's guide to image analysis www.biorxiv.org/content/10.64898/2026.03...
First 24 hours of embryonic development in 9 different animal species: (From left to right) Zebrafish, Sea urchin, Black widow spider, Tardigrade, Sea squirt, Comb jelly, Parchment tube worm, Roundworm, Slipper snail. Credit to @tessamontague.bsky.social & Zuzka Vavrušová. #ZebrafishZunday #devbio 🧪
Thread 15: Neural Crest (focusing specifically on neural)
Again, I learned this information and compiled it from my notes on the Neural unit in my biology advisor's 2024 dev bio class.
This thread will largely focus on Path 1 Neural Crest Cells. (1/n)
Please check out our new preprint! Using single cell analysis paired with HCR to visualize transcript localization we have identified cell and tissue-specific expression of various genes encoding tubulins, kifs, and dyneins during neural crest development!
Stages of embryo development
How to draw an owl: Draw some circles. Draw the rest of the fucking owl.
It's slightly upsetting that many online diagrams of a blastocyst turning into an embryo are very 'how to draw an owl'
