We're hiring! This is a unique opportunity to translate our understanding of neural computation - from circuit-level mechanisms to computational principles - into the human brain, through the establishment of cutting-edge human neural recording capabilities with collaborators in London and abroad.

We’re hiring a Group Leader!

Join us to lead a transformative initiative in human systems neuroscience.

Find out more and apply ⤵️

www.sainsburywellcome.org/content/curr...

Grumpy from Disney's Snow White and the 7 dwarves.

Let's talk about "grumpy lab person". Many labs have them. With an eye to keeping science at its most rigorous, they cross the line into criticism that's too harsh. They are the ones who risk killing your scientific spirit. They are reviewer 2. /1

Reduced rank regression for neural communication: a tutorial for neuroscientists Reduced rank regression (RRR) is a statistical method for finding a low-dimensional linear mapping between a set of high-dimensional inputs and outputs. In recent years, RRR has found numerous applica...

Bichan Wu (@bichanw.bsky.social) & I wrote a tutorial paper on Reduced Rank Regression (RRR) — the statistical method underlying "communication subspaces" from Semedo et al 2019 — aimed at neuroscientists.

arxiv.org/abs/2512.12467

Happy holidays from the Duan Lab!
We celebrated with some delicious and spicy Thai food :)

Those I cannot find on bluesky but also inspired our work:

Paul Glimcher
Xinying Cai
Paul Cisek
Karel Svoboda
Nuo Li
Zengcai Guo
Shaul Druckmann
Simon Musall
Lucas Pinto
Geoffrey Schoenbaum
And many more!

For theoretical, analytical, and experimental inspirations, thanks to:

@camillopadoasch.bsky.social @benhayden.bsky.social @jpillowtime.bsky.social @annechurchland.bsky.social @laklab.bsky.social
@constantinoplelab.bsky.social @flickerfusion.bsky.social @dr-stan.bsky.social and many others!

Neuronal Activity in Orbitofrontal Cortex during Trinary Choices under Risk Economic choice entails computing and comparing the subjective values of different goods. Orbitofrontal cortex (OFC) is thought to contribute to both operations. However, previous work focused almost ...

New ms on trinary choices! Somewhat surprisingly, our monkeys’ choices satisfied IIA (independence of irrelevant alternatives). In OFC, decision variables were represented in the same way under trinary and under binary choices. This property implies IIA.

www.biorxiv.org/content/10.1...

Work led by amazing postdocs Oliver Gauld and Chaofei Bao!
In collaboration with @jerlich.com, @clopathlab.bsky.social and many others!

A frontal motor circuit for economic decisions and actions Flexible behaviour requires transforming abstract cognitive representations, such as value preferences, into concrete motor actions. During economic decision-making, individuals evaluate options to gu...

New preprint from the lab!
A frontal motor circuit for economic decisions and actions:
www.biorxiv.org/content/10.6...

We use a novel task in mice, cortex-wide imaging and optogenetics, NPX recording and modelling to reveal a circuit mechanism that transforms abstract decisions to spatial actions.

Me! :D

Changes to the 2026 and 2027 Work Programmes With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...

Great news! Reasonable policy updates from #ERC

erc.europa.eu/news-events/...

Going to #Cosyne2025? Check out our researchers’ posters and talks:

www.sainsburywellcome.org/web/content/...

@cosynemeeting.bsky.social

Mice dynamically adapt to opponents in competitive multi-player games Competing for resources in dynamic social environments is fundamental for survival, and requires continuous monitoring of both 'self' and 'others' to guide effective choices. Yet our understanding of ...

First preprint from our lab! An @jerlich.bsky.social collaboration

We developed novel frameworks to study multi-agent decisions in mice.

Mice flexibly shift their decision preference under social competition, by integrating real-time self and opponent information!

www.biorxiv.org/content/10.1...

This is really really useful thanks Mark! Can I be added please :)

Can I be included as well? Thanks!