Chromatin-focused genetic and chemical screens identify BRPF1 as a targetable vulnerability in Taxol-resistant triple-negative breast cancer - Experimental & Molecular Medicine Triple-negative breast cancer (TNBC) is a challenging type of breast cancer that lacks targeted treatment options. Researchers aimed to understand why some TNBC cells become resistant to the chemother...

🎉 Excited to share that a new article led by my colleague Özlem is now online!

In this study, she explored epigenetic vulnerabilities in Taxol-resistant triple-negative breast cancer using the CRISPR and chemical screening approach. 🧬🎗️

www.nature.com/articles/s12...

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity - Nature A population of TRAIL-positive astrocytes in glioblastoma contributes to an immunosuppressive tumour microenvironment and this mechanism can be targeted with an engineered oncolytic virus to improve o...

Related study:
"Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity"
www.nature.com/articles/s41...

Targeting Astrocytes Could Boost Glioblastoma Treatment A subtype of astrocytes has been identified as a therapeutic target to enhance tumor immunity and extend survival in glioblastoma.

"Targeting Astrocytes Could Boost Glioblastoma Treatment"
#Glioblastoma
#TRAIL

www.insideprecisionmedicine.com/topics/oncol...

New Research Uncovers Cellular Ecosystems and Evolutionary Paths in Glioblastoma Study reveals how glioblastoma evolves uniquely in each patient, offering new insight into therapy resistance and tumor growth.

"New Research Uncovers Cellular Ecosystems and Evolutionary Paths in Glioblastoma"
www.insideprecisionmedicine.com/topics/oncol...

May is Brain Tumor Awareness Month!
Check out this new preprint on TMZ resistance and epigenetic regulation in glioblastoma.👇🏻

#BrainTumorAwarenessMonth
#BrainTumorStrong