Check out our new preprint on IRES studies (www.biorxiv.org/content/10.6...). We show a recently proposed IRES “toolbox” results in mRNA annotation errors and false-positive IRES activities. We provide an alternative set of robust approaches. (1/4)

Evaluating the reliability of tools for mRNA annotation and IRES studies www.biorxiv.org/content/10.64898/2026.03...

DOGE ends America’s golden age of biomedical research Biomedical research impacts all of us. I became curious about how drugs work after my mom was diagnosed with rheumatoid arthritis when I was a small boy. She received “gold shots” as treatment, which ...

My story: I’m a single father and cancer researcher whose wife died of a rare cancer. Science and biomedical research is personal to me. Here is my op-ed in my hometown newspaper. Pls fwd.

www.vindy.com/opinion/edit...

Roles of P-body factors in Candida albicans filamentation and stress response Author summary In the dimorphic fungal pathogen C. albicans, the hyphal phenotype strongly correlates with pathogenicity. While transcriptional control of hyphal growth has been extensively studied, c...

Another one from the McManus lab. Congrats, Melissa! journals.plos.org/plosgenetics...

Deciphering the landscape of cis-acting sequences in natural yeast transcript leaders Abstract. Protein synthesis is a vital process that is highly regulated at the initiation step of translation. Eukaryotic 5′ transcript leaders (TLs) conta

Latest paper from the McManus lab just out. academic.oup.com/nar/article-...