Improved red blood cell storage quality of blood from donors carrying the hypermorphic PIMT I120 variant Reader environment loaded

This paper has been a long time in the making. I'm glad to finally share it.
Working with the D’Alessandro lab, we investigated how #PIMT (PCMT1) variation affects red blood cell storage biology, uncovering a protective effect of the V120I variant on storage quality. #NMR @labvogeli.bsky.social

We are excited to announce the first in-person “A to Z Meeting - Ludwig Conference on Alternative Nucleic Acid Conformations in Health and Disease.” September 28th-October 2nd, Oxford, UK #RNA
For registration, visit the website:
atozconference2026.my.canva.site

Lab #Christmas dinner

Zα and Zβ domains of ADAR1 and ZBP1 bind to G-quadruplexes with low micromolar affinity While it is well established that the Zα domains of ADAR1 and ZBP1 proteins bind Z-form prone nucleic acid, it has also been shown that the Zα domain of ADAR1 binds DNA G-quadruplexes. However, no bin...

We uncover the first evidence that the long-mysterious Zβ domain of #ADAR1 binds G-quads, a surprising twist that reshapes how we think about ADAR targeting—opening new directions for understanding the links between innate immunity and splicing regulation. #NMR #RNA
www.biorxiv.org/content/10.1...