Background of DNA strand with logos of King's College London and the Leverhulme Trust and text 4 March 2026 Mechanosensing of epithelial cells: curvature, confinement and memory Professor Sylvain Gabriele University of Mons Force Talks Mechanics of Life Leverhulme DSP seminar series

Our next #ForceTalk is with Prof Sylvain Gabriele @sgabriele.bsky.social exploring "Mechanosensing of epithelial cells: curvature, confinement and memory"

📅 4 March 2026
🕒 15:00 - 16:00 GMT

Online & open to all 👉 www.kcl.ac.uk/events/force...

#mechanobiology @kingsnmes.bsky.social

Thank you so much Christopher 😊

Beautiful work from @rouxlab.bsky.social on the mechanical adaptation of epithelial tissues to multiscale curvature 👏🏻 Congrats to @marineluciano.bsky.social and all co-authors !

🚀 Very happy to see our research article “Tube feet dynamics drive adaptation in sea star locomotion” out in PNAS !
👉🏼 www.pnas.org/doi/10.1073/...

Fantastic collab with Patrick Flammang (UMONS), Sina Heydari (California State), Stanislav N. Gorb (Kiel Univ), and Eva Kanso (Univ Southern California)

The place to be 👇🏼👇🏼👇🏼

Sylvain Gabriele nommé « Professeur de recherche Francqui » pour la période 2025-2028 - Faculté / FS La Fondation Francqui a sélectionné Sylvain Gabriele, chargé de cours au Département de Chimie de la Faculté des Sciences de l’UMONS, pour le prestigieux mandat de Professeur de recherche Francqui. Ce...

I am delighted to share that I have been awarded the Francqui Research Professorship 🥳 This achievement is above all a collective success and I sincerely thank all the researchers of my lab www.cellmechanobiology.com, past and present, for their incredible work!

web.umons.ac.be/fs/fr/sylvai...

New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...

Thanks a lot Sam 😊

Thanks Edouard 😊

Thank you @halloulab.bsky.social !

The actin cortex acts as a mechanical memory of morphology in confined migrating cells - Nature Physics Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenv...

Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳

Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻

Enjoy the reading www.nature.com/articles/s41...

New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering

🔬 Excited to share our new publication in Soft Matter about hydrogel dimensionality to investigate mechanobiology. This paper with @marineluciano.bsky.social is part of the themed collection “Pioneering Investigators” - Lab website : www.cellmechanobiology.com

👉🏼 pubs.rsc.org/en/content/a...

@sarawickstrom.bsky.social

🎤Mechanical regulation of cell states

bsky.app/profile/cell...

My lab is co-organizing the CellMech2025 conference @cellmech2025.bsky.social. I’m excited to announce that the scientific program is now online!
👉🏼 cellmech2025.org/programme/

There’s still time to submit your abstract for the Scientific Art Contest and compete for prizes !

Have you ever wondered what happens when a sea star carries a backpack full of beads? You can now find out: « Tube feet dynamics drive adaptation in sean star locomotion » www.biorxiv.org/cgi/content/...

How multiscale curvature couples forces to cellular functions - Nature Reviews Physics Structure and function of biological tissues are closely intertwined. This Review surveys the challenges in uncovering critical physical elements involved in the mechanical regulation of curved tissue...

Luciano, M., Tomba, C., Roux, A., & Gabriele, S. (2024). How multiscale curvature couples forces to cellular functions. Nature Reviews Physics, #EpithelialMechanicsReveiw

Paper 1: @sgabriele.bsky.social lab placed cells on wavy substrates (20-50µm) to demonstrate the impact of curvature on cell thickness ➡️ nudging nucleus shape ➡️ revealing mechanoadaptation.

Happy to share our new publication in
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...

🚨Only a few hours left to register for @cellmech2025.bsky.social, deadline by March 16, 2025 ! 👇🏼

Time is flying, hurry up guys !

a man is walking down a dirt road in a field ALT: a man is walking down a dirt road in a field

⚠️⏳ There are less than 2 weeks left to submit your abstract!!

Hurry up and submit here! 👇🏻

cellmech2025.org/abstracts/

Join us online on Tuesday, February 25, for this exciting DGZ workshop on #celladhesion and #mechanobiology 👇🏼

Check out our latest paper in Advanced Science 🥳, where we use viscoelastic hydrogels to better understand how spatial confinement and matrix viscoelasticity jointly regulate cell migration: lnkd.in/diRstW2B Great collaboration between UMONS and @giusciccone.bsky.social @manuelsalmeron.bsky.social

The 10th edition of CellMech 2025, which my lab is co-organizing in Sept-Oct ‘25, has officially opened the abstract submission portal! cellmech2025.org

We are thrilled to announce our amazing list of keynote speakers, who will help us to make this conference a major event in mechanobiology!

Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems!

www.biorxiv.org/content/10.1...

Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris

Any 3D systems?👇

Congrats Julia and the team, impressive work !

Yamini @yamini-ravichan.bsky.social changed the topology of Hydra to show that actin orientational defects of Hydra induce the full program of head regeneration: www.science.org/doi/10.1126/...
Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.

And here is pre-print 2/2! *HYDRA: HYdrogel Dispensing with Robotic Automation* - a scalable solution for drug testing. Great work by 1st author
@eloisa_torchia and team with help from the labs of
@sgabriele.bsky.social Elisa Cimetta and Johan Lind biorxiv.org/content/10.1...

Really looking forward to visit the Salmeron’s lab at the Institute for Bioengineering of Catalonia @ibecbarcelona.eu at Barcelona tomorrow ! Thanks to @manuelsalmeron.bsky.social and @giusciccone.bsky.social for their kind invitation !