My first Bluesky paper post! I’m pleased to announce the publication of our single-nucleus atlas of adult neurons from wild-type and long-lived, better performing insulin receptor (daf-2) mutants, by Jon St. Ange and Yifei Weng et al.DOI: 10.1016/j.xgen.2024.100720

Please add me!

More great work by Mirre!

I found this out while reading for a historical review, even many classical articles on the field of medical sciences are simply not available, which I did not expect.

I double on that. Seems like a topic that has unfortunately been missing in conferences I have attended to this year.

Welcome here!

THank you for making this happen. Could you add me?

Very cool Tim! I am starting to make publication on the app, if you could add me it would be awesome. Perhaps my publications were not carrying the proper terms for your filter too?

What would you recommend to a newbie by Borges, Cortazar and Asimov. I can read in Spanish so I suspect I will gravitate towards the original versions.

This is the first strong evidence showing that caloric restriction can significantly increase maximum lifespan in rodents (1935). This is a modified version of the classical tab, designed for easier readability. Whether or not you work on dietary restriction, what stands out to you in these results?

Could I be added to the Starter Pack as well? Thanks!

Big update to the Aging Research starter pack. Many new folks joining every day, so challenging to keep up. Related starter packs by @brunetlab.bsky.social and @paigeonthebrain.bsky.social‬. Networks are built by self-reinforced expansion and amplification.
go.bsky.app/PcreQSa

Thanks Patrick, this is awesome. Very useful efforts to grow the network in the platform.

For similar topics, I recommend following accounts like @agingdoc.bsky.social @willmair.bsky.social @brunetlab.bsky.social @ctmurphy1.bsky.social @thevilchezlab.bsky.social @jorisdeelen.bsky.social @korolchuklab.bsky.social @mirresimons.bsky.social @dvalenzano.bsky.social

Since Weismann, breakthroughs in our understanding have largely come from the work of Haldane, Williams, and Hamilton. Yet, much remains to uncover. Yet here’s an old letter by Weismann I found in a German antique shop—one of my treasured discoveries.

Weismann proposed that aging evolved through group selection. He argued that aging is selected to eliminate old individuals, thereby improving the population's overall health. Critics later highlighted the circularity of the argument: if aging didnt exist, there would be no individuals to remove 🧵

What was Weismann thinking? He observed that smaller creatures often live shorter lives, while flying animals tend to live longer. Fascinated, he offered his own explanations and even predicted a limit to how many times somatic cells could divide (the Hayflick limit)🧵

However, the publication above is rather the essay itself. The first publication of his assay was published by the Society which hosted the event, in the Tageblatt der 54. Versammlung Deutscher Naturforscher und Ärzte🧵

Weismann wrote in German, which was a leading language in biological thought during the 1880s. His first exploration on aging, titled 'On the Duration of Life', was presented at the Assembly of German Naturalists/Physicians on September of 1881. I’m fortunate to own an original copy 🧵

Why do living things age? Have you heard of August Weismann? As someone passionate about the evolutionary biology of aging and the history of the field, I thought my first Bsky should highlight him—the first to propose Darwinian ideas on how aging might be shaped by natural selection🧵

Aging starter pack!

go.bsky.app/5UXXaDA

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This is very interesting. While I have not studied the rise of Hitler in detail, I have heard that, in hindsight, the chain of events leading to it seems clear. However, the book Berlin Diary highlights how, when living through such events, their significance is not always immediately apparent.

This is very interesting. While I have not studied the rise of Hitler in detail, I have heard that, in hindsight, the chain of events leading to it seems clear. However, the book Berlin Diary highlights how, when living through such events, their significance is not always immediately apparent.

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