@biorxivpreprint.bsky.social T-bet Expressing B cells are Key Determinants of Protective Immunity Against Norovirus Infection @scripps.edu @thepenkpanther.bsky.social
www.biorxiv.org/content/10.6...

Commensal enteric virome regulates intestinal carbohydrate digestion and absorption Lin et al. show that the enteric virome, dominated by bacteriophages, can autonomously activate host immune signaling to modulate intestinal metabolic responses. Their findings identify the enteric vi...

Virome regulates nutrient sensing

Enteric virome, dominated by bacteriophages, can autonomously activate host immune signaling to modulate intestinal metabolic responses and regulate carbohydrate digestion & absorption
www.cell.com/cell-host-mi...

Influenza virus hitches a cellular ride to the heart Influenza virus is associated with severe cardiac complications, yet mechanisms of disease, including how the virus traffics from lungs to the heart, have remained elusive. In a recent Immunity paper,...

Influenza virus hitches a cellular ride to the heart

Preview of @cp-immunity.bsky.social paper demonstrating that pro-DC3 cells ferry influenza virus to the heart, infecting cardiomyocytes and triggering damage via type I interferon signaling
www.cell.com/cell-host-mi...

Very happy to share our latest work in @bloodadvances.bsky.social: Antibiotic treatment limits survival of peripheral and bone marrow B-cell populations ashpublications.org/bloodadvance...

Love this!

Exciting energy from the next generation of physician-scientists at the 2025 @washumedicine.bsky.social Pediatric
Research Retreat! 🚀 Early career faculty are driving innovation across disciplines. The future of child health research is bright! 🌟#PedsResearch #AcademicMedicine #FutureLeaders #WashU

Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice - Nature Microbiology Colonic goblet cell-associated passages allow translocation of live bacteria to other organs in early life, potentially leading to beneficial impacts.

Out now! Live bacteria can translocate to other tissues via Colonic goblet cell-associated passages which may be beneficial to the host!

#MicroSky #MicrobiomeSky 🦠

www.nature.com/articles/s41...

Adding insult to injury during RSV infections Mucosal Immunology Podcast · Episode

It’s #MucosalMonday and time for our monthly podcast. This episode features @cjohansson-lab.bsky.social, along with hosts @marionbrunck.bsky.social and @ashu-mangalam.bsky.social. Find it on your favorite platform, including spotify: open.spotify.com/episode/4Ng1...

An oral norovirus vaccine tablet was safe and elicited mucosal immunity in older adults in a phase 1b clinical trial An oral norovirus vaccine tablet is safe and induces strong mucosal and systemic immune responses in adults aged 55 to 80 years.

In the US alone, each year, norovirus causes ~20 million acute gastroenteritis cases, 70,000 hospitalizations, up to 800 deaths, at a cost of ~$10.6 billion annually.
An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity
www.science.org/doi/10.1126/...

Just joined @bsky.app! Looking forward to connecting with neonatology & scientific communities on this platform.