Thomas Pereira presented a poster at the U of Michigan Undergraduate Research Symposium last week! So proud of him and the work he’s been doing!!🧑‍🔬🥳

Check out our newest publication (collab w Waters) in JASMS titled Improved Methods for Recording Accurate Collision Cross Sections Using Cyclic Ion Mobility-Mass Spectrometry!

Link: pubs.acs.org/doi/10.1021/...

Introduction to mass spectrometry 1 Click to launch & play an online audio visual presentation by Prof. Brandon T. Ruotolo on Introduction to mass spectrometry 1, part of a collection of multimedia lectures.

Prof. Brandon Ruotolo created instructional/tutorial videos covering the basics of mass spectrometry in collab w/ Henry Stewart Talks! MC questions and learning objectives added soon to package!

V1: doi.org/10.69645/OBM...
V2: doi.org/10.69645/FEX...
Subscription is needed to access these videos.

Last week we celebrated Dr. Nicole Rivera Fuentes successfully defending her thesis in January!! The 24th graduate of the Ruotolo lab!! We wish you the best at Merck! 🍾🍾🥳🥳 @nicolerf.bsky.social

Ruotolo lab hang!! Always a great time with this group of people💃🕺

Happy holidays from the Ruotolo lab! Had a wonderful time at our lab holiday dinner this past Monday!

More pictures! Including Dr. Brandon Ruotolo :)

Our lab had a great time at the Anachem Symposium this past week! Congratulations to our very own Saachi Kheterpal for winning best graduate poster! 🥳🥳

Check out our newest article in Analytical Chemistry about high-throughput mAb peptide mapping with HPLC and cIM-MS!

Link: pubs.acs.org/doi/10.1021/...

Congratulations to @nicolerf.bsky.social for winning the Early Career Researcher Travel Award!! So proud🍾🍾 #ASMS2025

As ASMS begins, we have a number of posters and presentations from our lab that we are excited to share! Here’s a list our research and where to find it! 🤩 #ASMS2025

Energy-Dependent Changes in Ion Mobility Peak Width Reveal Stability Shifts in Ribonucleic Acid Stem Loops Ribonucleic acids (RNAs) are becoming increasingly important to our understanding of cellular biology and our search for new or improved biotherapeutics. However, the dynamic and polydisperse nature o...

Check out our newest article on RNA and ion mobility! ✨

Link: pubs.acs.org/doi/full/10....

Check out this article using cyclic ion mobility to isolate and identify cardiolipin subspecies in biological samples!

Link: doi.org/10.3389/fphy...

Check out our newest publication on a quantitative comparison between solution and gas-phase RNA unfolding!

DOI: 10.1021/acs.analchem.5c01148
Link: pubs.acs.org/articlesonre...

Check out our most recent publication evaluating membrane mimetics! With nIM-MS!!✨✨

Link: pubs.acs.org/doi/abs/10.1...

Tonight we celebrated our 23rd grad from the lab, Devin! He defended his thesis last week!! Wish you all the best on your future endeavors!🥳🥳🎉🎉

Congratulations to our newest grad, Dr. Anna Anders! Wish you the best of luck and you will be missed!!🥳🥳🥳🎉🎉🎉

Molecular insights into the interaction between a disordered protein and a folded RNA | PNAS Intrinsically disordered protein regions (IDRs) are well established as contributors to intermolecular interactions and the formation of biomolecul...

Check out the newly published PNAS article regarding the biophysical characterization of a disordered protein, a folded RNA, and their complex! ✨✨
Link: www.pnas.org/doi/10.1073/...
DOI: 10.1073/pnas.2409139121

We are the Ruotolo Research Group at the University of Michigan. We use native ion mobility-mass spectrometry, and collision induced unfolding (CIU) to study proteins and the complexes they form. We are excited to begin sharing our research news with our colleagues on Bluesky!