Differences in clinical outcomes among patients with mold fungemia

🔁 Repost
🔗 https://bit.ly/4sryNrv

Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients | NEJM Nirmatrelvir–ritonavir has been shown to reduce progression to severe illness from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in unvaccinated high-risk outpatients. The effectiven...

In two open-label trials, nirmatrelvir–ritonavir did not reduce the incidence of hospitalization or death among vaccinated higher-risk participants with SARS-CoV-2 infection.

www.nejm.org/doi/full/10.... #IDSky

Review Article Spinal Epidural Abscess Figure 1. Spinal Epidural Abscess and Contiguous Infection of Nearby Structures.

Spinal epidural abscess is an infection in the epidural space commonly caused by 𝘚𝘵𝘢𝘱𝘩𝘺𝘭𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘢𝘶𝘳𝘦𝘶𝘴. Symptoms include back pain, neck pain, fever, and neurologic symptoms. Prompt evaluation is important. Learn more: nej.md/4tq1kxx

#InfectiousDisease #Neurology

After sustaining a laceration while jumping into Coastal Gulf waters, a 74-year-old man presented to the ED with 3 days of worsening painful ecchymosis with crepitus on his right leg and right arm. A diagnosis of 𝘝𝘪𝘣𝘳𝘪𝘰 𝘷𝘶𝘭𝘯𝘪𝘧𝘪𝘤𝘶𝘴 necrotizing soft-tissue infection was made. nej.md/4dGOOF3

#idboardreview PLWH on ritonavir-boosted darunavir (DRV/r), emtricitabine/tenofovir TAF developed centripetal obesity, dorsocervical fat pad, facial fullness, proximal muscle weakness x6wks. Mild asthma & recently started daily inhaler. ⬇️serum cortisol, ⬇️ACTH. Likely inhaler-drug interaction? #idsky

Severe Symptomatic Hypercalcemia Caused by Antibiotic Bead Placement | Annals of Internal Medicine: Clinical Cases Severe hypercalcemia is a rare but potentially fatal complication of calcium sulfate antibiotic beads, particularly in patients with impaired renal function. We present the case of a 77-year-old man w...

Interesting case…

www.acpjournals.org/doi/10.7326/... #IDSky

Pentagon to Stop Requiring Members of Military to Get Flu Vaccines

www.nytimes.com/2026/04/21/u... #IDSky

Repeat women’s winner Sharon Lokedi, also from Kenya.

Admittedly difficult to type and process a record at the same time lol

Well for som thing different, love from the finish of the Boston Marathon - repeat winner John Korir from Kenya sets a new Boston record at 2:01:52

Why scientists are nervous about fungi They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them.

They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them. n.pr/4sEdj9w

ID fellows: Join us for the next virtual Fellows Case Conference on Tuesday, April 28 at 3pm ET.

Explore a unique ID case alongside presenters Kelly Hallowell, MD, and Sophia Lewis, MD, PhD, and discussant Luis Parra-Rodriguez, MD.

Register: https://bit.ly/4sC1zUY

Yeah I don’t know much about her but seems like a step up from where we’ve been.

Trump Administration Eyes Erica Schwartz to Lead CDC The health agency is facing leadership turmoil and controversy over vaccine guidance.

www.wsj.com/politics/pol... #IDSky

More Americans doubt vaccine safety than trust it, POLITICO Poll finds Health Secretary Robert F. Kennedy Jr.’s views are commonplace across the land.

😢

www.politico.com/news/2026/04... #IDSky

Trends in Long Duration Antibiotic Prescribing Following Focused Outpatient Antimicrobial Stewardship Efforts Across a Large Healthcare Enterprise AbstractBackground. Outpatient antibiotic stewardship programs (ASP) are recommended by the CDC and Joint Commission. We analyzed the impact of annual, foc

Outpatient antibiotic stewardship programs (ASP) are recommended by the CDC and Joint Commission.

In CID, authors analyzed the impact of annual, focused syndrome-specific ASP interventions on trends in long-duration antibiotic prescribing. https://bit.ly/3Oik1nK

Line graph showing the percentage distribution of Candida species from 2016 to 2024. Candida albicans is the most common species in most years, declining from about 36% to 32%. Candida glabrata increases overall, rising from about 25% in 2016 to a peak around 34% in 2024. Candida parapsilosis fluctuates between roughly 8% and 17% before declining to about 8% by 2024. Candida tropicalis and unspecified/other species remain relatively stable at lower levels (about 6–12%). Multiple-species infections decrease slightly over time. Candida auris is absent before 2022 and then increases to about 5% by 2023–2024.

Candida glabrata emerges as the most common cause of candidemia: analysis of a large hospital-based database, United States, 2016–2024

academic.oup.com/cid/advance-...

Jeremy Gold & colleagues at CDC Mycotic Diseases Branch, @jessicalittlemd.bsky.social and @drluiso.bsky.social

Kennedy broadens vaccine advisory panel's role to focus on risks U.S. Health ​Secretary Robert F. Kennedy Jr. on Thursday issued a new charter for a CDC vaccine advisory committee that ‌expands the role of the panel to include a focus on vaccine risks and supposed ...

On the ACIP front…

www.reuters.com/legal/litiga... #IDSky

A reminder to slow down and notice what’s blooming around us. 🌸 ☀️

Spots are filling up fast for the 2026 UW Implementation Science Summer Institute! Register soon, and don't forget to tell your friends 📅 ➡️ bit.ly/UWISInstitut... for all the details! #impsci #implementationscience #Seattle #UniversityofWashington @uofwa.uw.edu @uwdgh.bsky.social @uwsph.bsky.social

UW study found echinococcus multilocularis in Pacific Northwest coyotes 😳

www.washington.edu/news/2026/04... #IDSky

Rifampin-Induced Loss of Glucocorticosteroid Therapeutic Effect | Annals of Internal Medicine: Clinical Cases Drug–drug interactions between rifampin and glucocorticosteroids are uncommonly reported in the literature but can have significant impact on patient management. We report a case in which this drug–dr...

Interesting case of rifampin interaction with prednisone worsening RA symptoms…

www.acpjournals.org/doi/10.7326/... #IDSky

Age-Specific Risk of Herpes Zoster in Adults Aged ≥18 Years With Comorbid Conditions—A Retrospective Cohort Study in the United States A retrospective US study in immunocompetent adults found that adults aged ≥30 years with asthma, chronic obstructive pulmonary disease, depression, diabete

Interesting look at the risk of zoster infection in younger populations with comorbidities…

Also, I’d like to meet the 50-59 year comparators who had no stress 😎

academic.oup.com/cid/advance-... #IDSky

Evaluation of the MEFIER Score in Identifying Patients at High Risk of Endocarditis in Enterococcus faecalis Bacteremia Among 549 Enterococcus faecalis bacteremia episodes, the MEFIER score failed to reliably rule out infective endocarditis, misclassifying 60% of cases as lo

per authors: Among 549 Enterococcus faecalis bacteremia episodes, the MEFIER score failed to reliably rule out infective endocarditis, misclassifying 60% of cases as low risk, whereas DENOVi misclassified only 5% while reducing echocardiography use.

academic.oup.com/ofid/article... #IDSky

Meet Abby Fessler, F3! #IDSky

Trained: U Penn

ID passion: STI prevention and treatment

❤️ UW ID Fellowship: The community - you're surrounded by faculty who are world experts in their fields, yet remain kind, humble, and approachable.

❤️PNW: It's beautiful! Gorgeous views right from your home 🤩🏔️

World Health Day 2026: Together for health. Stand with science On World Health Day 2026, celebrated on 7 April, WHO unites and mobilizes the world under the theme “Together for health. Stand with science.” celebrating the power of scientific collaboration to prot...

World Health Day, 4/7/2026

www.who.int/news-room/ev... #IDSky

More from the penicillin delabeling front, an international effectiveness-implementation trial:

“Multidisciplinary adoption of inpatient penicillin DOC was safe & significantly improved penicillin prescribing and reduced use of WHO restricted antibiotics.”

academic.oup.com/cid/advance-... #IDSky

Much Ado About Macrolides: Revisiting Empiric Atypical Coverage in Non-severe Community-acquired Pneumonia Whitney Hartlage, PharmD, Priya Nori, MD; Much Ado About Macrolides: Revisiting Empiric Atypical Coverage in Non-severe Community-acquired Pneumonia, Clini

Excellent work by one of our great UW ID pharmacists, Whitney Hartlage.

Are we overusing macrolides for CAP?

academic.oup.com/cid/advance-... #IDSky

Raw Farm added that it was conducting its recall “under protest” and in order to chart “a path forward.”

Daily reminder that the shingles vaccine kinda sucks for a day or so, but actual shingles is way worse and can leave you sleepless and in chronic pain for months to years