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Posts by Matt Kirkcaldie

I'm not joking when I say mRNA technology is more important than "AI" and it's a tragedy we're throwing billions into one while our government is aggressively defunding the other.

2 days ago 14917 5516 114 106

Possibly “💩”?

2 days ago 1 0 0 0

Fascinating, revelatory insights to heterogeneous regulation of neurovascular coupling in the mouse brain. Congratulations @agnesland.bsky.social and @carandinilab.net on a tour-de-force I would not have imagined was possible. I hope you find the culprit neurons!

5 days ago 2 0 0 0
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Opinion | Don’t Use A.I. to Do This

Absolute perfection from @colsonwhitehead.com.

5 days ago 374 68 12 12
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Whole organism 3D mapping reveals universal branching topology and biophysical optimization governs vascular and nervous system development

Read about our work here: www.biorxiv.org/content/10.6...

1 week ago 44 9 1 1

and of course follow @adammorton.bsky.social for informed and incisive commentary

6 days ago 0 0 0 0
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Politicians and media can’t imagine a fossil-fuel free world - and it’s holding Australians back from huge EV savings | Adam Morton Australia is well behind other countries in embracing clean cars – it’s past time we kicked into gear on going electric

I wonder when, if ever, we will have any genuine action or leadership over the transition to EVs. Federal Labor apparently stand for nothing that’s not OK with the centre right. www.theguardian.com/environment/...

6 days ago 1 0 1 0
Topographic organization of LC-NE axons.

Topographic organization of LC-NE axons.

This example neuron has a massive projection to the cerebral cortex, but you’ll notice it doesn’t go everywhere in the brain. By analyzing many individual neurons (below), we found a beautiful topographic organization: dorsal cells sent axons to the front of the brain, ventral cells to the back. 6

1 week ago 34 7 1 1

all of them

1 week ago 5 0 1 0

Absolutely love this idea of sensorimotor loop maintenance during REM sleep twitches. You could argue that cortical magnification makes a body part more likely to be involved in evenly distributed random cortical activity, but the authors link it to dialogue with the brainstem and cerebellum.

2 weeks ago 3 0 0 0
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Stature

2 weeks ago 1 0 0 0

It can be a bit of a “scold” community but I think far more of the accounts here are real people, instead of bots. And a lot of us enjoy your pictures and marine science.

2 weeks ago 8 0 0 0

Yeah, nah.

2 weeks ago 0 0 0 0
The Amazing Disk II Controller Card | Big Mess o' Wires

Problem is, the control logic and format are done by the clever controller card in the Apple II - that's why they could offer floppy drives more cheaply than most at the time. A PC 5.25" floppy drive will expect the disk to have a completely different format. www.bigmessowires.com/2021/11/12/t...

2 weeks ago 2 0 0 0

MASSIVELY underrated

2 weeks ago 2 0 0 0
Schematic of theta waves and gamma packets recorded from the mouse visual cortex

Schematic of theta waves and gamma packets recorded from the mouse visual cortex

How does the visual cortex coordinate neural activity over spatial and temporal scales? We found broad θ waves organize local γ bursts and spiking, forming a flexible spatiotemporal code to multiplex feedforward/feedback signals. Now out in full @natcomms.nature.com: doi.org/10.1038/s414... 🧵

4 weeks ago 32 11 2 0

Gee, I wonder which

3 weeks ago 3 0 0 0

"ORGERNIZER"

3 weeks ago 1 0 0 0

Sounds like the cycle of abuse

3 weeks ago 1 0 1 0
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Every neuroscientist should read this. Understanding previous science in the context of a series of evolving brain paradigms is like turning the light switch on in a cluttered room.

3 weeks ago 8 1 0 0
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Climate disasters are getting worse and costing more. The question isn’t if we can afford to act, but why Govs allow the biggest climate vandals to avoid paying their fair share. Today I tabled @TheAusInstitute petition calling for a Climate Disaster Levy now. #auspol #politas

4 weeks ago 361 117 1 7

More power to you!

1 month ago 2 1 1 0

I know, I know it’s serious

1 month ago 0 0 0 0
Front cover of the Strategic Examination of Research & Development review report. Purple background with pink title text "Ambitious Australia". The graphics below the text are some curvy, bubble-like shapes with what seems to be a sunset viewed through some drops of liquid. That is, a distorted view of the horizon … a metaphor?

Front cover of the Strategic Examination of Research & Development review report. Purple background with pink title text "Ambitious Australia". The graphics below the text are some curvy, bubble-like shapes with what seems to be a sunset viewed through some drops of liquid. That is, a distorted view of the horizon … a metaphor?

The Government released the final report of the Strategic Examination of R&D yesterday. It's called "Ambitious Australia"🙃

Haven't read much, yet, but it says we should fund the ARC more. Like every single previous review.

Can we got on with it & do that, now?

www.industry.gov.au/publications...

1 month ago 61 32 5 5

Love this.

1 month ago 2 0 0 0

Good point, I should have said. In the author comments I highlighted obvious elements like repetitions, and the section without references, and asked them to clarify genAI usage. My comments to the editor were similar to this thread (e.g. tone and ref patterns), and recommended major revision.

1 month ago 1 0 0 0
The "is this ... a pigeon?" meme with the title Peer Review, a bookish young man regarding a butterfly tagged "Gen-AI slop", asking innocently "is this ... a scientific article?"

The "is this ... a pigeon?" meme with the title Peer Review, a bookish young man regarding a butterfly tagged "Gen-AI slop", asking innocently "is this ... a scientific article?"

So – last week I had a peer review to do for a journal from a major publisher, an overview article by well published researchers.
It was late, so I stayed back to work on it. Some hours in, a few things snapped into focus, and I realised that large chunks had been “written” by generative AI. (1/12)

1 month ago 10 4 1 0

So I hope this was of interest to anyone who took the time to read it. Please share your views and experiences, I’d appreciate it. I think of it as community support for people who still care about quality over expedience. (12/12 end)

PS: no genAI was used to write this.

1 month ago 4 0 1 0
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Writing with AI We put ChaptGPT to the test

But my attitude to *generative* AI text is “if you didn’t bother writing it, why should I bother reading it?” I can’t source that quote, but the earliest similar phrase I found is here: (11/12) ia.net/topics/writi...

1 month ago 4 0 1 0
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No statement about AI use accompanied the manuscript. I actually don’t object to people using AI tools to smooth their expression and catch anomalies. Science is very anglocentric, and non-English-speakers are unfairly judged by their fluency rather than their science. (10/12)

1 month ago 2 0 1 0